An observational study in SARS Virus and Long-Term Survivors, sponsored by Peking University People's Hospital. Status unknown at 1 site in China. Per ClinicalTrials.gov, last updated 2018-02-26.
Sponsored by Peking University People's Hospital · Observational
SARS-CoV has caused severe epidemic respiratory disease in human populations. By July 2003, a total of 8,096 probable cases of SARS had been reported including 774 deaths in 27 countries, around one-third of which were health care workers (HCWs). Previous studies have been reported about long-term impacts of SARS infection, including lung function deficiency, steroid-induced osteonecrosis, reduced exercise capacity, and impairment in health-related quality of life (HRQoL). HCWs, especially nurses, have been reported to experience greater psychological distress, particularly increased levels of posttraumatic stress symptomatology (PTSS). But the very complex impacts of this fatal infection on HCWs have not been fully elucidated. It is thus important to follow these occupational patients to detect and manage multi-organ sequelae and functional impairment.
Health care workers who were working at Peking University People's Hospital during the SARS epidemic in 2002-2003 will be enrolled.
Exclusion Criteria:
First-line HCWs infected during the SRAS-CoV pandemic in Peking University People's Hospital, China. Diagnose was further confirmed by SARS-CoV seropositive results.
1. Coworkers of the infected HCWs, who also exposed to SARS patients or specimens. Infection was further excluded by SARS-CoV seronegative results. 2. Healthy controls matched for age, sex and disease condition, but without exposures to SARS virus.
All-cause disability
Disabilities arising from physical injuries and/or mental stresses
Time frame: Evaluations would be finished within 90 days after enrollment.
Cardiopulmonary function
The interrelationship between the workings of the heart and lung organs would be assessed by assessed by 6MWT (6-min walk test)
Time frame: Evaluations would be finished within 90 days after enrollment.
Life Life quaities mental distress
Quality of life would be assessed by the Medical Outcomes Study 36-item short form version 2 (SF-36)
Time frame: Evaluations would be finished within 90 days after enrollment.
Plan to share: Undecided
This study is status unknown, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
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Severe Acute Respiratory Syndrome→
Peking University People's Hospital