ClinicalTrials.gg
Status unknownNCT03431298Updated Aug 28, 2018

The Benefit of Functional Movement Control for Patients With Knee Osteoarthritis

An interventional study of Aerobic exercise & movement control and Aerobic exercise in Knee Osteoarthritis, sponsored by National Yang Ming Chiao Tung University. Status unknown at 1 site in Taiwan. Open to participants aged 40 Years to 75 Years. Per ClinicalTrials.gov, last updated 2018-08-28.

Sponsored by National Yang Ming Chiao Tung University · Not applicable, Interventional, and Supportive care

The sponsor has not verified this record recently (last verified Jan 2018), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
40 Years to 75 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 89 studies in Osteoarthritis, Knee with a site in Taiwan — 12 open to participants now, 14 under way, 3 of them phase 3. Osteoarthritis, Knee · Taiwan.

Planned enrollment
40th of 83
60 · median 60
Started
2018
with 10 others
No phase
49 of 89
6 open now
Registered
30th of 89
by date

Among the 89 studies in Osteoarthritis, Knee with a site in Taiwan, this one is the 40th largest by planned enrollment of the 83 interventional ones that give a count, is one of 11 that started in 2018, is one of 49 with no phase, and was the 30th registered.

Osteoarthritis, Knee

3,292 studies on the registry are indexed under Osteoarthritis, Knee; 623 are open to participants now.

Browse Osteoarthritis, Knee studies →

Open to participants now

12 of the 89 studies in Osteoarthritis, Knee with a site in Taiwan are open now. Recruiting first, the newest first:

7 more — sign in →

All 12 open studies →

A study can be open while its sites in Taiwan have not opened yet or have stopped. Only those recruiting at a site in Taiwan →

Who these studies take

Of the 382 Osteoarthritis, Knee studies recruiting now, 176 (46%) set no upper age limit and 113 (30%) stop at 75 or younger; 19 take children under 18; 39 take healthy volunteers.

This study: 40 Years to 75 Years · all sexes · no healthy volunteers.

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02

Study summary

The study purpose is to explore the effect of functional movement control for patients who have stage II or III degenerative knee joint disease and also physical inactive. Half of patients will receive aerobic exercise and functional movement control training in combination, while the other will simply receive aerobic exercise.

Read the detailed description

Physical inactivity, which is a common phenomenon among patients with degenerative knee joint disease has been proved a predictor of increased symptoms and poor general health. However, changing the lifestyle of people with this disease who is physical inactive is still a problem which has not been solved. Knee pain may act as barrier to engage in physical activity and can influence patient's movement performance.

The different effectiveness between the aerobic exercise and functional movement control training.

Aerobic exercise has been proved could improve knee pain for the patients with degenerative knee joint disease.

The functional movement control training could improve knee alignment during walking and other functional activities to increase patient's movement awareness.

03

Conditions studied

  • Knee Osteoarthritis

Keywords

  • Knee osteoarthritis
  • Physical activity
  • Exercise
04

Who can participate

Ages eligible
40 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Participant who was diagnosed has knee osteoarthritis
  • Above 40 years old
  • Participant who didn't achieve at least 150 min moderate intensity physical activity level per week

Exclusion criteria

Exclusion Criteria:

  • Patients with walking disability
  • Cannot complete 8 weeks intervention program
  • Received arthroscopy or other surgery before 6 months
05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
60 participants (estimated)

Study arms

  • Experimental
    Aerobic exercise & movement control

    The duration of intervention is 8 weeks. * Individualized functional movement control training is 60 min/week * Aerobic exercise is 60 min/week

    Behavioral: Aerobic exercise & movement control

  • Active comparator
    Aerobic exercise

    The duration of intervention is 8 weeks. * Frequency: 2 times/ week * Duration: 60min/ time

    Behavioral: Aerobic exercise

Interventions

  • BehavioralAerobic exercise & movement control

    The aerobic exercise content is no different between the experimental group and the active comparator group. The movement control is individual training which divided into fourths progressing sessions. * First, lumbo-pelvic and hip dynamic direction control. * Second, trunk muscle groups, hip muscle groups and thigh muscle groups extensibility control. * Third, trunk muscle groups and hip muscle groups through range control. * Fourth, functional movement control training

  • BehavioralAerobic exercise

    The aerobic exercise will organized in groups. Each group has 6-8 persons. The exercise form is fixed at each time. The description of exercise form is as below: * 10 min Warm up * 40 min Aerobic exercise (which focus on lower extremity muscle strengthening and increasing muscle endurance) * 10 min Cool down

06

What researchers measure

Primary outcomes

  1. reaching proportions of the level of health enhancing physical activity

    the recommended level of health enhancing physical activity is at least 150 min of moderate intensity physical activity per week

    Time frame: up to 6 months after intervention

Secondary outcomes

  1. Partial foot pressure as a percentage of body weight

    The area footprinted during gait was divided into 6 parts according to the average foot areas of subject. Then, the partial foot pressure as a percentage of body weight was calculated as the average value during the stance phase of each step in each part as a percentage of the body weight.

    Time frame: Baseline and up to 1 week after intervention

  2. Partial foot area as a percentage of body mass index

    The area footprinted during gait was divided into 6 parts. The partial foot area as a percentage of body mass index was calculated as the average value during the stance phase of each step in each part as a percentage of the body mass index.

    Time frame: Baseline and up to 1 week after intervention

  3. Gait Cadence

    the number of steps per minute

    Time frame: Baseline and up to 1 week after intervention

  4. Walking speed

    the velocity of single step

    Time frame: Baseline and up to 1 week after intervention

  5. Single leg stance time

    the time of the stance phase of each foot

    Time frame: Baseline and up to 1 week after intervention

  6. Step length

    the distance between the first point of contact of a limb with the ground and the first point of contact of the limb on the opposite side

    Time frame: Baseline and up to 1 week after intervention

  7. Step width

    the distance between the centre of the first heel contact and the following one calculated perpendicularly to the direction of the horizontal axis drawn between the feet

    Time frame: Baseline and up to 1 week after intervention

  8. Axis angle

    the angle formed by the medial tangent of the foot and the line from the second/third toe to the center of the heel

    Time frame: Baseline and up to 1 week after intervention

  9. The Knee injury and Osteoarthritis Outcome Score

    A questionnaire to assess the patient's opinion about their knee and associated problems.

    Time frame: Baseline and up to 1 week after intervention

  10. Sort Form-12v2 Healthy Survey

    12 question to measure functional health and well-being from the patient's point of view

    Time frame: Baseline and 1, 3, 6 month after intervention

07

Study locations

1 of 1 sites recruiting
  • Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
    New Taipei City, Taiwan
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Mar 2018 (actual). Primary completion is estimated for Dec 2018, 9 months after the start.

Of 1,111 non-industry interventional studies with no phase under Osteoarthritis, Knee, half reached primary completion within 18 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 36. This study's planned 9 months is below that.

Counting every sponsor, half of 1,251 studies reached it within 18 months; a quarter within 8 and three quarters within 36.

How these figures are worked out, and which studies are left out of them.

Registered
Jan 28, 2018
First posted
Feb 13, 2018
StartActual
Mar 1, 2018
Primary completionEst.
Dec 31, 2018
CompletionEst.
Dec 31, 2018
Last update
Aug 28, 2018
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Aug 28, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03431298
Responsible party
Sponsor
First posted
Feb 13, 2018
Start date
Mar 1, 2018
Primary completion
Dec 31, 2018 (estimated)
Completion
Dec 31, 2018 (estimated)
Last update
Aug 28, 2018

Study contacts

Chuan-Hsin Yen, BS
Contact
Yanlisa0728@gmail.com
+886933301155
Wen-Yin Chen, PhD
Contact
wychen@ym.edu.tw
Wen-Yin Chen, PhD
principal investigator · National Yang-Ming University The Department of Physical Therapy and Assistive Technology

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2018. You cannot join it, but the record below documents what was studied.

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