An observational study in Hepatocellular Carcinoma, sponsored by Humanitas Clinical and Research Center. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-02-13.
Sponsored by Humanitas Clinical and Research Center · Observational
¹¹C-choline positron emission tomography/computed tomography (PET/CT) has been used in patients with some types of solid cancers, but few data are available in patients undergoing hepatectomy for hepatocellular carcinoma (HCC). The aim of this study was to analyze the prognostic value of metabolic imaging data by using ¹¹C-choline PET/CT in patients with HCC before hepatectomy.
Our prospectively maintained liver unit database was queried for patients with HCC preoperatively staged with ¹¹C-choline PET/CT. This metabolic imaging modality was performed in addition to standard abdominal CT or magnetic resonance imaging. Several PET/CT parameters were recorded and analyzed. Univariate and multivariate analyses were performed to identify whether those PET/CT parameters could be predictors of overall survival (OS) and disease-free survival (DFS) of HCC patients.
Patients affected by HCC candidate to surgical resection that were preoperatively staged with ¹¹C-choline PET/CT.
Exclusion Criteria:
Surgery of the liver: removal of a given part of the liver affected by hepatocellular carcinoma
Also known as: Hepatic resection; liver resection.
Identification of PET/CT parameters that can be predictors of survival
Identification of specific PET/CT parameters that can be used as independent predictors of overall and/or disease-free survival
Time frame: From date of surgery until the date of first documented progression or date of death from any cause, whichever came first assessed up to 72 months
No study locations are listed for this record.
This study is completed, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
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Humanitas Clinical and Research Center