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TerminatedNCT03421951BURSTUpdated Mar 19, 2020

Change in Pain and Quality of Life Following SCS for Chronic Pain

An observational study in Pain, Chronic, Pain, Radiating and Pain, Back, sponsored by KM Clinical Research Group. Terminated at 1 site in United States. Open to participants aged 18 Years to 85 Years. Per ClinicalTrials.gov, last updated 2020-03-19.

Sponsored by KM Clinical Research Group · Observational

Why this study was terminated
Sponsor withdrew funding
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
26
Ages
18 Years to 85 Years
Sex
All
01

Study summary

Study Title Subject-reported treatment efficacy and procedure satisfaction (steps) study.BURST study- a prospective observational clinical study examining the changes in quality of life and pain following spinal cord stimulation for the treatment of chronic intractable lower back and lower limb pain.

Read the detailed description

Objectives The primary objective is changes in lower back and/or lower limb pain patient-reported satisfaction with procedure outcome and treatment efficacy to reduce pain levels following an orthopedic procedure for knees, hips, shoulders, elbows, wrists, or anklesspinal cord (SCS) stimulation. Secondary objectives include changes in physical health, quality of life, and quality of life and pain-related prescription medication usage.

Design and Outcomes This is a prospective observational single-arm study to access the primary outcome variable of lower back and/or lower limb patient satisfaction with procedure outcomes as measured using a modified MacNab scale. Patients will have presented to their healthcare providers with knee, hip, shoulder, elbow, wrist, or ankle pain and will have elected and been assigned a medically-appropriate surgical procedure as part of their standard of care. It is possible for subjects to have multiple areas of pain and subsequent surgeries, and subjects have the option of completing surveys for all medically-indicatedmedically indicated areas being treated.pain

IIIntervention and Duration There will be no study intervention. Subjects will only be monitored and evaluated for pre and post-operative satisfaction, pain, physical activity levels, quality of life, and medication use levels. Subjects will be followed for 12 months following their SCS stimulation implant procedure.

Sample Size and Population Investigators aim for a minimum population size of 1,500 in order to give statistical significance with results. Subjects will be stratified by surgical procedurearea of chronic pain.

02

Conditions studied

  • Pain, Chronic
  • Pain, Radiating
  • Pain, Back
  • Pain Syndrome

Keywords

  • spine
  • lower limb
03

Who can participate

Ages eligible
18 Years to 85 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Study population will be patients who have already been prescribed a trial spinal cord stimulator implant procedure to treat their lower back or lower limb pain.

Inclusion criteria

Prescribed spinal cord stimulator implant by their healthcare provider. Previous conservative care such as physical therapy or chiropractic care that failed to provide adequate pain relief.

Willing and able to adhere to the protocol of the study including the survey timeline.

Between the ages of 18-85 years.

Exclusion criteria

Exclusion Criteria:

Unwilling to sign Informed Consent and comply with protocol

04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
26 participants (actual)
Patient registry
No
05

What researchers measure

Primary outcomes

  1. Change in Pain Levels

    Change in self-reported pain levels

    Time frame: 12 months post-permanent spinal cord stimulator implantation

  2. Change in quality of life

    change in self-reported quality of life

    Time frame: 12 months post-permanent spinal cord stimulator implantation

Secondary outcomes

  1. Change in prescription pain medication use

    change in opioid medication use to control pain

    Time frame: 12 months post-permanent spinal cord stimulator implantation

06

Study locations

1 site
  • KM Clinical Research Group
    Murrieta, California 92563, United States
07

Registry details

Key details

Study ID
NCT03421951
Lead sponsor
KM Clinical Research Group
Responsible party
Kate McLellan (Principle Investigator, KM Clinical Research Group) — Principal investigator
First posted
Feb 5, 2018
Start date
Nov 1, 2017
Primary completion
Jan 31, 2019
Completion
Feb 1, 2019
Last update
Mar 19, 2020

Study contacts

Kate McLellan, PhD
study director · KM Clinical Research Group

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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