CClinicalTrials.gg
CompletedNCT03418298Updated May 21, 2020

Prehabilitation in Patients With Esophageal or Gastric Cancers

An interventional study of Prehabilitation group in Esophageal Cancer and Gastric Cancer, sponsored by Cliniques universitaires Saint-Luc- Université Catholique de Louvain. Completed at 1 site in Belgium. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-05-21.

Sponsored by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

Objectives: The primary objective of this study is to assess the feasibility of a internet-based preoperative exercise program in patients with esophageal or gastric cancers. Secondary objectives are to evaluate the effects of this preoperative program on functional capacity, anxiety and depression, quality of life and fatigue Methods: This feasibility study will be conduct at University Hospital Saint-Luc in Brussels. Twenty patients with esophageal or gastric cancers will participate in internet-based program 3 sessions per week. Each session will combine aerobic and resistance training. Moreover, inspiratory muscle strengthening (IMT) will be performed daily. The researcher will conduct weekly telephone calls to educate and motivate subjects. Assessments will be performed at baseline, one day before surgery, 1 month and 3 months after surgery. The following parameters will be measured: functional capacity, quality of life, fatigue, anxiety and depression.

02

Conditions studied

  • Esophageal Cancer
  • Gastric Cancer

Browse trials for

03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Diagnosis of esophageal cancer or gastric cancer requiring surgery
  • More than 18 years
  • Able to read, write and understand French or English
  • Time before surgery > 2 weeks

Exclusion criteria

Exclusion Criteria:

  • Surgical emergency
  • Cognitive or neuropsychiatric diseases
  • Neuromuscular or orthopedic disorders limiting exercises
  • Cardiopulmonary disease contraindicating exercises
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    Prehabilitation group

    Subjects will carry out a preoperative internet-based program including aerobic and resistance training three sessions per week

    Behavioral: Prehabilitation group

Interventions

  • BehavioralPrehabilitation group

    Subjects will performed an internet-based exercise program before surgery

05

What researchers measure

Primary outcomes

  1. Retention rate

    Proportion of patients who complete the tele-prehabilitation and all assessments

    Time frame: At study completion (3 months after surgery)

  2. Attendance

    (Number of completed sessions/Number of planned sessions) x 100

    Time frame: At study completion (3 months after surgery)

  3. Program satisfaction

    Program satisfaction will be evaluated by a questionnaire including items about internet program

    Time frame: At study completion (3 months after surgery)

  4. Percentage of patients who experienced one or more adverse events

    Adverse events will be evaluated by listing adverse events that occur (e.g. fall, injury or exercise-related symptom)

    Time frame: At study completion (3 months after surgery)

  5. Recruitment rate

    ratio of the number of the recruited patients to the number of eligible patients

    Time frame: At study completion (3 months after surgery)

Secondary outcomes

  1. Change in functional capacity

    Functional capacity will be assessed by 6-minute walk test

    Time frame: Baseline, one day before surgery, 1 and 3 months after surgery

  2. Change in quality of life

    Quality of life using the Functional Assessment of Cancer Therapy-General (FACT-G). Each item is rated from 0 (not at all) to 4 (very much) with a total score ranging from 0 to 102. The higher the score, the better the QoL.

    Time frame: Baseline, one day before surgery, 1 and 3 months after surgery

  3. Change in fatigue

    Fatigue using the Functional Assessment of Cancer Therapy-Fatigue questionnaire (FACIT-F). Each item is rated from 0 (not at all) to 4 (very much) with a total score ranging from 0 to 52. The higher the score, the lower the fatigue.

    Time frame: Baseline, one day before surgery, 1 and 3 months after surgery

  4. Change in anxiety and depression

    Anxiety and depression using the Hospital Anxiety and Depression Scale (HADS). Scores for each subscale (depression and anxiety) are summed-up and range from 0 to 21. Values from 0-7 indicate normal levels, 8-10 are border values, and values from 11-21 are considered to be pathological

    Time frame: Baseline, one day before surgery, 1 and 3 months after surgery

06

Study locations

1 site
  • Cliniques universitaires Saint-Luc
    Brussels, Woluwé-Saint-Lambert 1200, Belgium
07

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03418298
Lead sponsor
Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Responsible party
Sponsor
First posted
Feb 1, 2018
Start date
Feb 27, 2018
Primary completion
Nov 1, 2019
Completion
Dec 15, 2019
Last update
May 21, 2020

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2020. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion