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CompletedNCT03417635Updated Dec 5, 2023

Meditation Strategies, Attention, and Mobility in Older Adults

An interventional study of Guided focused attention and Acoustic music in Mobility Limitation, sponsored by Western University, Canada. Completed at 1 site in Canada. Open to participants aged 60 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-12-05.

Sponsored by Western University, Canada · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
43
Allocation
Randomized
Ages
60 Years and older
Sex
All
01

Study summary

Approximately 30% of community-dwelling older adults experience one or more falls per year, resulting in injuries, loss of independence, and reduced quality of life. While there are known physiological risk factors for falls, including poor balance and altered gait patterns, it is now recognized that impaired cognitive functioning is also a risk factor for falls. Within the broad construct of cognition, one specific domain that has been focused on in the falls literature is attention. The literature suggests that improving attention in those at-risk for falls may reduce older adult's risk of falling.

Read the detailed description

The current study aims to investigate the impact of meditation strategies on measures of attention and electrical signals in the brain in older adults. Investigators will recruit older adults who are living in the community. Participants will be assigned to one of two groups: 1) guided focused attention group, or 2) music group (control group). All participants will complete three in-person sessions per week and then be encouraged to practice independently on the other days in the week, for a total of four weeks.The current study focuses on focused attention meditation strategies, as it is recommended for beginner-level meditators. This will include training to be able to focus on one's breathing for 20 minute sessions. Focused attention meditation has been found to increase levels of executive functioning and attention. Participants will complete mobility and cognitive assessments at both the beginning and end of the intervention. These will be completed in the retirement homes for convenience. Participants will also attend an in-lab session to complete electroencephalogram (EEG) testing at both timepoints.

02

Conditions studied

  • Mobility Limitation

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Keywords

  • Meditation
  • Cognitive assessment
  • Executive function
  • Older adults
  • Randomized control trial
  • Mobility
03

Who can participate

Ages eligible
60 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  1. minimum 60 years of age,
  2. minimum completed high school,
  3. must be comfortable writing and reading English,
  4. be able to walk independently,
  5. must be right-handed (for EEG analysis),
  6. score 6+/8 on the instrumental activities of daily living scale,
  7. score >24/30 on the Mini-Mental Status examination.

Exclusion criteria

Exclusion Criteria:

To be included, participants must NOT:

  1. have a diagnosis of neurodegenerative disease,
  2. have a diagnosis of cognitive impairment (e.g., MCI),
  3. have a diagnosis of a psychiatric condition,
  4. have had a concussion in the last 12 months,
  5. have had a stroke,
  6. have musculoskeletal or joint disease,
  7. experience dizziness or loss of balance,
  8. have visual, auditory, or somatosensory impairment, or
  9. a recent history (past 2 years) of regular meditation practice (1 or more times per week) or include a meditation component in their religious practice.
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
43 participants (actual)

Study arms

  • Experimental
    Guided focused attention

    Participants will take part in a guided focused attention practice led by the researcher. This will include strategies used in meditations where participants focus on their breathing. More specifically, they will be instructed to close their eyes and focus on the sensation of breathing in one area of the body for the entire session. They will be given reminders throughout the session to remain on task (focusing on the breath) and not to let their thoughts wander. Participants will be asked to either sit on a chair or cushion on floor to ensure they are comfortable to sit still for the session, but not so much that they might fall asleep.

    Behavioral: Guided focused attention

  • Active comparator
    Acoustic music

    Participants will be instructed to listen to a prepared soothing acoustic music track. The sessions will be led by a researcher. Participants will be asked to close their eyes and relax while listening to the music. Participants will be asked to sit on a chair or cushion on floor to ensure they are comfortable to sit still for the session, but not so much they might fall asleep This group is used as active control group to control for socialization in group settings and any effects of consciously relaxing for the meetings.

    Behavioral: Acoustic music

Interventions

  • BehavioralGuided focused attention

    Participants will meet for 20 minute group sessions with 6-10 participants in each group. There will be three meetings a week for a four week period. The focused attention practice itself will last for 20 minutes with instructions being given during the 20 minute period. All sessions will occur in the retirement home in a community room to ensure the sessions are easily accessible to the participants.

  • BehavioralAcoustic music

    Participants will meet for 20 minute group sessions with 6-10 participants in each group. There will be three meetings a week for a four week period. The acoustic music track itself will last for 20 minutes with instructions being given during the 20 minute period. All sessions will occur in the retirement home in a community room to ensure the sessions are easily accessible to the participants.

05

What researchers measure

Primary outcomes

  1. Change in sustained attention

    Measured by performance on sustained attention task.

    Time frame: 4 weeks

Secondary outcomes

  1. Change in global attention

    Measured by electrophysiological measures of attention.

    Time frame: 4 weeks

  2. Change in mobility

    Measured by the Timed Up and Go test.

    Time frame: 4 weeks

  3. Change in mobility and balance

    Measured by the Short Physical Performance Battery.

    Time frame: 4 weeks

  4. Change in memory

    Measured with the Rey Auditory Verbal Learning Test

    Time frame: 4 weeks

  5. Change in conflict resolution

    Measured with the stroop task

    Time frame: 4 weeks

  6. Change in set-shifting

    Measured with the trail making task

    Time frame: 4 weeks

  7. Change in working memory

    Measured with the digit span task

    Time frame: 4 weeks

06

Study locations

1 site
  • Community
    London, Ontario, Canada
07

References and documents

Publications

  • Martin K, Thomson R, Blizzard L, Wood A, Garry M, Srikanth V. Visuospatial ability and memory are associated with falls risk in older people: a population-based study. Dement Geriatr Cogn Disord. 2009;27(5):451-7. doi: 10.1159/000216840. Epub 2009 May 7. PubMed 19420939 ↗
  • Nagamatsu LS, Liu-Ambrose TY, Carolan P, Handy TC. Are impairments in visual-spatial attention a critical factor for increased falls risk in seniors? An event-related potential study. Neuropsychologia. 2009 Nov;47(13):2749-55. doi: 10.1016/j.neuropsychologia.2009.05.022. Epub 2009 Jun 6. PubMed 19501605 ↗
  • Nagamatsu LS, Munkacsy M, Liu-Ambrose T, Handy TC. Altered visual-spatial attention to task-irrelevant information is associated with falls risk in older adults. Neuropsychologia. 2013 Dec;51(14):3025-32. doi: 10.1016/j.neuropsychologia.2013.10.002. PubMed 24436970 ↗
  • Wallace, B. A. (2006). The attention revolution: Unlocking the power of the focused mind. Somerville, Massachusetts: Wisdom Publications, Inc.
  • Ainsworth B, Eddershaw R, Meron D, Baldwin DS, Garner M. The effect of focused attention and open monitoring meditation on attention network function in healthy volunteers. Psychiatry Res. 2013 Dec 30;210(3):1226-31. doi: 10.1016/j.psychres.2013.09.002. Epub 2013 Oct 14. PubMed 24135553 ↗
  • Tsai MH, Chou WL. Attentional orienting and executive control are affected by different types of meditation practice. Conscious Cogn. 2016 Nov;46:110-126. doi: 10.1016/j.concog.2016.09.020. Epub 2016 Oct 3. PubMed 27710818 ↗
  • Nagamatsu LS, Ford SD. Can meditation improve attention in older adults? Study protocol for a 4-week proof-of-concept intervention. Pilot Feasibility Stud. 2019 Feb 11;5:22. doi: 10.1186/s40814-019-0413-x. eCollection 2019. PubMed 30788136 ↗

Individual participant data

Plan to share: No

08

Registry details

Key details

Study ID
NCT03417635
Lead sponsor
Western University, Canada
Responsible party
Lindsay Nagamatsu (Assistant Professor, Western University, Canada) — Principal investigator
First posted
Jan 31, 2018
Start date
Jan 2, 2019
Primary completion
Aug 31, 2019
Completion
Aug 31, 2019
Last update
Dec 5, 2023

Study contacts

Lindsay S Nagamatsu, PhD
principal investigator · Western University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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