CClinicalTrials.gg
Status unknownNCT03394547PUMMPUpdated Jun 13, 2018

Pulsed Electromagnetic Field Treatment for Painful Periods

An interventional study of Allay and Placebo in Dysmenorrhea, sponsored by Birmingham Women's NHS Foundation Trust. Status unknown at 1 site in United Kingdom. Open to female participants aged 16 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-06-13.

Sponsored by Birmingham Women's NHS Foundation Trust · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Jun 2018), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
16 Years and older
Sex
Female
01

Study summary

A single-centre, randomised controlled, double blind study comparing use of the Allay pulsed shortwave therapy treatment versus a placebo device or no treatment for management of primary dysmenorrhea.

Read the detailed description

Women participating in the trial will be randomly allocated to any of the three arms of the study.

  • Treatment for 2 menstrual cycles using the PSWT Allay device (BioElectronics Corp, Frederick USA)
  • Treatment for 2 menstrual cycles using a placebo device
  • No treatment. If they are allocated to a device both the participant and the clinician will be blinded at to weather they are using the active device or the placebo.

Primary Outcome measures are:

  • A reduction in dysmenorrhea as measured by the highest pain score on a 10cm visual analogue scale.
  • A reduction in average pain score on a 10cm visual analogue scale
  • A reduction in use of analgesia as recorded in a pain diary
  • Improvement in quality of life as measured through a validated quality of life assessment tool (SF-36 questionnaire)

    • Improvement in menstrual symptoms as recorded through a validated questionnaire (the Modified Menorrhagia Multi-attribute Scale (MMAS)).
  • Device acceptability as measured on a 5-point Likert scale ranging from "unacceptable" to "totally acceptable".
  • Impact upon associated cyclical symptoms as recorded in a patient symptom diary
02

Conditions studied

  • Dysmenorrhea

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03

Who can participate

Ages eligible
16 Years and older
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Female with persistent (>3months) cyclical period pain associated with menstruation (defined as 5 or more on VAS).
  • Able to give written, Informed consent
  • Able to wear device and keep up-to-date records of use
  • Agrees to attend follow up
  • If currently using hormonal contraception agrees to continue on the same dose for the duration of the trial.

Exclusion criteria

Exclusion Criteria:

  • Age under 16 years.
  • Trying to conceive or \<6 weeks post partum
  • Currently participating or planning to participate in another clinical trial
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Triple (Participant, Care provider, Outcomes assessor)
Enrollment
60 participants (estimated)

Study arms

  • Active comparator
    Active Treatment

    Treatment for 2 menstrual cycles using the pulsed shortwave therapy Allay® device (BioElectronics Corp, Frederick USA)

    Device: Allay

  • Placebo comparator
    Placebo

    Treatment for 2 menstrual cycles using a placebo device which is identical in appearance to the active device but does not emit any pulsed shortwave therapy.

    Device: Placebo

  • No intervention
    No treatment

    No intervention is given and a menstrual diary is completed for 2 cycles.

Interventions

  • DeviceAllay

    pulsed shortwave therapy treatment for painful periods

  • DevicePlacebo

    A placebo device is given which is identical to the Allay device but emits no pulsed shortwave therapy.

05

What researchers measure

Primary outcomes

  1. A reduction in dysmenorrhea as measured by the highest pain score on a 10cm visual analogue scale.

    Measured as highest pain score on a 10cm visual analogue scale

    Time frame: 2 months

Secondary outcomes

  1. Impact upon associated cyclical symptoms

    Measured through the validated menstrual symptoms questionnaire the Menorrhagia Multi-Attribute Scale

    Time frame: 2 months

  2. Improvement in quality of life as measured through a validated quality of life assessment tool (SF-36 questionnaire).

    Measured through a validated quality of life questionnaire (SF36)

    Time frame: 2 months

  3. Device acceptability as measured on a 5-point Likert scale ranging from "unacceptable" to "totally acceptable".

    Measured by those allocated a device on a 5-point Likert scale ranging from "unacceptable" to "totally acceptable".

    Time frame: 2 months

  4. Reduction in use of analgesia

    Measured through a record of analgesia used during menstrual cycle

    Time frame: 2 months

06

Study locations

1 of 1 sites recruiting
  • University of Birmimgham
    Birmingham, United Kingdom
    • Justin Clark · Contact
    Recruiting
07

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03394547
Lead sponsor
Birmingham Women's NHS Foundation Trust
Collaborators
BioElectronics Corporation
Responsible party
Thomas Justin Clark (Chief Investigator, Birmingham Women's NHS Foundation Trust) — Principal investigator
First posted
Jan 9, 2018
Start date
Nov 3, 2017
Primary completion
Oct 1, 2018 (estimated)
Completion
Oct 1, 2018 (estimated)
Last update
Jun 13, 2018

Study contacts

Justin Clark
Contact
t.j.clark@doctors.org.uk
07967724697
helen stevenson
Contact
h_stevenson27@hotmail.com
07854031663
Justin Clark
principal investigator · Birmingham Women's NHS Foundation Trust

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is status unknown, as verified in Jun 2018. You cannot join it, but the record below documents what was studied.

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