An observational study in Postoperative Cognitive Dysfunction, sponsored by RenJi Hospital. Status unknown at 2 sites in China. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2020-03-10.
Sponsored by RenJi Hospital · Observational
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Among 57 studies in Postoperative Cognitive Complications with a site in China — 14 open to participants now, 16 under way, none of them phase 3. Postoperative Cognitive Complications · China.
Among the 57 studies in Postoperative Cognitive Complications with a site in China, this one is the 19th largest by planned enrollment of the 24 observational ones that give a count, is one of 4 that started in 2018, is one of 24 observational ones, and was the 17th registered.
260 studies on the registry are indexed under Postoperative Cognitive Complications; 55 are open to participants now.
Browse Postoperative Cognitive Complications studies →14 of the 57 studies in Postoperative Cognitive Complications with a site in China are open now. Recruiting first, the newest first:
Shanghai Geriatric Medical Center · Sites in China
Ages 65+
Peking University Shenzhen Hospital · Sites in China
Ages 60+ · Healthy volunteers
Zhuan Zhang · Sites in China
Ages 18+
West China Hospital · Sites in China
Ages 65–90 · Healthy volunteers
Nanjing First Hospital, Nanjing Medical University · Sites in China
Ages 18+
A study can be open while its sites in China have not opened yet or have stopped. Only those recruiting at a site in China →
Of the 34 Postoperative Cognitive Complications studies recruiting now, 22 (65%) set no upper age limit and 4 (12%) stop at 75 or younger; 2 take children under 18; 6 take healthy volunteers.
This study: 65 Years and older · all sexes · no healthy volunteers.
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57 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 1 2 · Phase 2 1 · Phase 3 2 · Phase 4 10
First in 2012; this study’s year is marked. 4 started in 2018.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 100 is close to the median of 100 across 113 observational studies indexed under Postoperative Cognitive Complications.
Median enrollment 220 across the 33 interventional studies, 213 across the 24 observational. Of the 17 that completed or were terminated, 1 (6%) have results posted.
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1 of 57 have an industry lead sponsor. The 10 most frequent:
RenJi Hospital is the lead sponsor of 550 studies on the registry; 247 are open to participants now.
RenJi Hospital has 8 studies filed under Postoperative Cognitive Complications — fewer than ten, so there is no comparison to draw.
5 of the studies in Postoperative Cognitive Complications with a site in China that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07643194Beijing Anzhen HospitalCohort Study of Postoperative Cognitive Dysfunction After Off-Pump Coronary Artery Bypass Grafting | 2026-11-24 |
| NCT07673978The Second Affiliated Hospital of Chongqing Medical UniversityEffect of Ciprofol Injection on Postoperative Cognitive Function | 2026-12-30 |
| NCT07135336Peking University Shenzhen HospitalIncidence of Postoperative Cognitive Decline in Patients With Preexisting Cognitive Impairment | 2027-01-01 |
| NCT05555693Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityCorrelation Between Postoperative Cognitive-related Adverse Reactions and Brain Metabolomic Characteristics in Elderly Patients | 2027-01-01 |
| NCT07895407Second Affiliated Hospital of Wenzhou Medical UniversityEffects of Ciprofol on Perioperative Neurocognitive Function in Elderly Patients Undergoing Daytime Surgery | 2027-03-01 |
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Among the 57 studies in Postoperative Cognitive Complications with a site in China, from their registry updates:
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The purpose of this study is to investigate whether preoperative pain is the risk factor of POCD in elder patients.
Postoperative cognitive dysfunction (POCD) occurs mainly in aged patients. The mechanism of POCD is not clear yet and no effective therapy method. In the present study, we conducted a single-center observational prospective cohort trial in elder patients who undergoing hip joint replacement surgery with general anesthesia to test our hypothesis that preoperative chronic pain is one of the risk factors of POCD after major joint replacement surgery.
Elderly patients underwent elective low limb surgery(hemiarthroplasty or total hip arthroplasty); Chronic pain duration >3 months.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
ASA physical status
The anaesthetists’ scale of health before surgery: I is healthy, II has a mild illness that is under control, III a severe one, IV a severe illness that is a constant threat to life. V and VI are used for the critically ill and for organ donors.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
POCD incidence 7 days (or before leaving hospital) after surgery
POCD incidence 7 days (or before leaving hospital) after surgery
Time frame: 7 days (or before leaving hospital)
POCD incidence 2 months after surgery
POCD incidence 2 months after surgery
Time frame: 2 months after surgery
Started Jan 2018 (actual). Primary completion is estimated for Mar 2020, 26 months after the start.
Of 76 non-industry observational studies under Postoperative Cognitive Complications, half reached primary completion within 27 months of starting (the median), counting those still running; a quarter within 11 and three quarters within 65. This study's planned 26 months is close to that.
Counting every sponsor, half of 76 studies reached it within 27 months; a quarter within 11 and three quarters within 65.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.
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Postoperative Cognitive Complications →