An interventional study of inspiratory muscle training in Pulmonary Hypertension, sponsored by Istanbul University. Completed at 1 site in Turkey. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2018-03-01.
Sponsored by Istanbul University · Not applicable, Interventional, and Treatment
Among 46 studies in Hypertension, Pulmonary with a site in Turkey — 6 open to participants now, 13 under way, 4 of them phase 3. Hypertension, Pulmonary · Turkey.
Among the 46 studies in Hypertension, Pulmonary with a site in Turkey, this one is the 23rd largest by enrollment of the 28 interventional ones that give a count, is one of 2 that started in 2017, is one of 8 with no phase, and was the 21st registered.
1,092 studies on the registry are indexed under Hypertension, Pulmonary; 244 are open to participants now.
Browse Hypertension, Pulmonary studies →6 of the 46 studies in Hypertension, Pulmonary with a site in Turkey are open now. Recruiting first, the newest first:
Marmara University · Sites in Turkey
Istanbul Mehmet Akif Ersoy Educational and Training Hospital · Sites in Turkey
Insmed Incorporated · Sites in Turkey, United States, Argentina and 27 more countries
United Therapeutics · Sites in Turkey, United States, Argentina and 30 more countries
Prof. Valérie Mc Lin · Sites in Turkey, United States, Australia and 13 more countries
A study can be open while its sites in Turkey have not opened yet or have stopped. Only those recruiting at a site in Turkey →
Of the 164 Hypertension, Pulmonary studies recruiting now, 100 (61%) set no upper age limit and 26 (16%) stop at 75 or younger; 39 take children under 18; 24 take healthy volunteers.
This study: 18 Years to 80 Years · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
46 studies; the count open now beside each. This study's row is marked.
A study in two phases is counted once above. Listed by phase, each with its combined phases: Phase 2 5 · Phase 3 15 · Phase 4 1
First in 2008; this study’s year is marked. 2 started in 2017.
This study's enrollment of 30 is below the median of 35 across 649 interventional studies indexed under Hypertension, Pulmonary.
Median enrollment 129 across the 28 interventional studies, 118 across the 17 observational. Of the 29 that completed or were terminated, 14 (48%) have results posted.
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27 of 46 have an industry lead sponsor. The 10 most frequent:
Istanbul University is the lead sponsor of 511 studies on the registry; 78 are open to participants now.
Of its 5 completed or terminated interventional studies of FDA-regulated products, 1 (20%) have results posted.
Istanbul University has 3 studies filed under Hypertension, Pulmonary — fewer than ten, so there is no comparison to draw.
2 of the studies in Hypertension, Pulmonary with a site in Turkey that are under way reach primary completion within a year, 1 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT03683186Phase 3United TherapeuticsA Study Evaluating the Long-Term Efficacy and Safety of Ralinepag in Subjects With PAH Via an Open-Label Extension | 2026-12 |
| NCT07667673Istanbul University - CerrahpasaMultimodality RV Phenotyping for Risk Stratification and Short-Term Outcomes in Group 1 PAH | 2027-02 |
Among the 46 studies in Hypertension, Pulmonary with a site in Turkey, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.
Pulmonary hypertension (PH) is a condition which is seen with hemodynamic differences, pulmonary vascular resistance and right heart failure. Patients with pulmonary hypertension have, dyspnea, physical inactivity, reduced condition and respiratory muscle dysfunction. Aerobic exercise programs in patients with pulmonary hypertension are reported to result in improved exercise capacity and endurance of the patients, improvement in WHO functional class and quality of life, increased peak workload and increased peripheral muscle function. In recent years, few studies have investigated the efficacy of inspiratory muscle training in patients with PH.The aim of this study is to investigate the effective of inspiratory muscle training on respiratory function, exercise capacity, physical activity and quality of life.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The New York Heart Association’s four classes of how much heart failure limits physical activity.
Studies set their own limit — many outside heart failure leave out class III–IV, while heart failure studies may ask for a particular class. Check the class this study names.
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
NYHA class (heart failure)
The New York Heart Association’s four classes of how much heart failure limits physical activity.
Studies set their own limit — many outside heart failure leave out class III–IV, while heart failure studies may ask for a particular class. Check the class this study names.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
COPD
Chronic obstructive pulmonary disease: long-term lung disease that makes it hard to breathe out, including emphysema and chronic bronchitis.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients will continue 8 weeks, 5 days, 2 times 15 minutes training program with %30 MIP at home.
Other: inspiratory muscle training
Patients will continue 8 weeks, 5 days, 2 times 15 minutes training program with 9 cmH2O pressure at home.
The treatment group received IMT. Patients were trained using an inspiratory threshold-loading device
mouth pressures
MIP and MEP
Time frame: 10 minutes
International Physical Activity Questionnaire-Short Form
Physical activity
Time frame: 10 minutes
Minnesota Living with Heart Failure Questionnaire
quality of life
Time frame: 15 minutes
Activity monitoring (Sense wear® Armband)
Metabolic holter
Time frame: 3 days
6 minute walking test
functional capacity
Time frame: 15 minutes
Plan to share: No — Results of the study will share with other researchers
No publications or documents are linked to this record.
Ran from Oct 2017 to primary completion in Feb 2018, 4 months.
Of 134 non-industry interventional studies with no phase under Hypertension, Pulmonary, half reached primary completion within 20 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 46. This study's 4 months is below that.
Counting every sponsor, half of 148 studies reached it within 23 months; a quarter within 9 and three quarters within 48.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Feb 2018. You cannot join it, but the record below documents what was studied.
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