An interventional study of SEE Training and GAZE Training in Psychopathy, Violent Aggressive Behavior and Emotional Problem, sponsored by University Hospital Tuebingen. Status unknown at 1 site in Germany. Open to male participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2017-12-26.
Sponsored by University Hospital Tuebingen · Not applicable, Interventional, and Treatment
Impaired recognition of affective facial expressions has been conclusively linked to antisocial and psychopathy. However, little is known about the modifiability of this deficit. This study aims to investigate whether and under which circumstances the proposed perceptual insensitivity can be addressed with a brief implicit training approach.
67 studies on the registry are indexed under Antisocial Personality Disorder; 10 are open to participants now.
This study's planned enrollment of 80 is below the median of 140 across 43 interventional studies indexed under Antisocial Personality Disorder.
Browse Antisocial Personality Disorder studies →University Hospital Tuebingen is the lead sponsor of 490 studies on the registry; 108 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
The training sequence comprises four weekly sessions using a modified dote-probe paradigm (fearful vs. neutral expression).
Behavioral: SEE Training
The GAZE training sequence comprises four weekly sessions using a modified dote-probe paradigm (averted vs. directed gaze).
Behavioral: GAZE Training
Participants are first presented with a fixation cross which indicates the beginning of a trial and is immediately followed by a bilateral presentation of a neutral and a fearful image (face) of the same model identity. The fearful expression is always replaced by an arrow pointing to the left or the right which remaines active until the participant indicates via button-press which direction the arrow is pointing to. The model identity, the position of the fearful cue and the arrow probe direction are pseudo-randomized across trials with no more than three identical sequential occurrences on each parameter. Each session consists of 360 trials in total, with 120 distinct trial types and three repetitions. Participants are trained with neutral and 75% fearful expressions only in the first session; the intensity of the fearful cue is successively decreased by 15% at every subsequent session.
Participants are first presented with a fixation cross, which indicates the beginning of a trial and is immediately followed by a bilateral presentation of a direct gaze-image (neutral face) and an image of a neutral face (same model identity) displaying deviated gaze. The averted gaze-face is always replaced by an arrow pointing to the left or the right which remaines active until the participant indicates via button-press which direction the arrow is pointing to. The model identity, the position of the fearful cue and the arrow probe direction are pseudo-randomized across trials with no more than three identical sequential occurrences on each parameter. Each session consists of 360 trials in total, with 120 distinct trial types and three repetitions. Participants are trained with direct and 100% averted gaze images only in the first session; the intensity of the deviated gaze cue is successively decreased by 20% at every subsequent session.
Animated morph task
Morphed images are presented, beginning with the neutral face that progresses into one of the six affective expressions. This procedure creates the impression of an animated clip depicting the development of facial emotive expressions. Participants are instructed to press a button as soon as they are able to identify the emerging expression.
Time frame: change from pre-treatment to post-treatment after 8 weeks
Unconscious processing of affective facial expressions during interocular suppression in a breaking Continuous flash suppression paradigm
Change in processing of unaware/unconsciously perceived emotional stimuli as assessed by number of faces correctly identified
Time frame: pre-treatment, after 8 weeks (post-treatment)
Eye-Tracking
Change in recognition and visual processing of emotional faces as indicated by raw scores and group means for dwell time, total dwell time, and time to first AOI (mouth/eye region) hit
Time frame: pre-treatment, after 8 weeks (post-treatment)
Ambivalence Task
Change in interpretation of ambiguous emotional faces as indicated by number of hostile judgments
Time frame: pre-treatment, after 8 weeks (post-treatment)
Emotional search paradigm
Assessment of implicit perceptual biases for and explicit categorization of facial expression in an emotional search paradigm (change pre- to post-intervention)
Time frame: pre-treatment, after 8 weeks (post-treatment)
Affective prosody
Change in recognition of non-verbal emotional aspects of language as assessed by number of correct classifications
Time frame: pre-treatment, after 8 weeks (post-treatment)
Multifaceted empathy test
Assessment of cognitive and emotional empathy (change pre- to post-intervention)
Time frame: pre-treatment, after 8 weeks (post-treatment)
Plan to share: No
Started Apr 2017 (actual). Primary completion is estimated for Mar 2019, 23 months after the start.
Of 25 interventional studies with no phase under Antisocial Personality Disorder, half reached primary completion within 53 months of starting (the median), counting those still running; a quarter within 29 and three quarters within 66. This study's planned 23 months is below that.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Dec 2017. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Antisocial Personality Disorder →
University Hospital Tuebingen →