An observational study in Frailty, Surgery and Older Patients, sponsored by Charite University, Berlin, Germany. Completed at 1 site in Germany. Open to participants aged 70 Years and older. Per ClinicalTrials.gov, last updated 2023-06-15.
Sponsored by Charite University, Berlin, Germany · Observational
Frailty is prevalent in older adults and may be a better predictor of post-operative morbidity and mortality than chronological age. Preoperative risk factors and physiological reserves were assessed on patients more than 70 years old who are scheduled for surgery under general or regional anesthesia. The aim of this retrospective analysis was to examine the impact of relevant geriatric assessments on adverse outcomes in older surgical patients.
The goal of this study is to analyze the effect of frailty status on postoperative outcomes. These include postoperative complications (only ICD-10 coded diagnoses), length of hospitalization (ward/ICU), disposition, and survival. The project will also attempt to find synergism between a positive frailty status and common medical conditions (e.g. diabetes, congestive heart failure, coronary artery disease, dementia, and kidney disease), as well as anesthesiological and surgical processes (e.g. duration and type of anesthesia, surgical risk, and surgical discipline). Different assessment tools will be analyzed regarding their predictive power and clinical practicability. This should help improve preoperative risk assessment and allow for the multidimensional (physical, cognitive, social) identification of relevant frailty characteristics in the perioperative setting. All outcome parameters, including admission and discharge periods, will be collected using coded information from our hospital database. There will be no follow-up measurements after hospital discharge.
1,229 studies on the registry are indexed under Frailty; 433 are open to participants now.
This study's enrollment of 25,000 is above the median of 211 across 503 observational studies indexed under Frailty.
Browse Frailty studies →Charite University, Berlin, Germany is the lead sponsor of 854 studies on the registry; 127 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Male and female patients with age 70 years and above scheduled for surgery
Inclusion Criteria:
Male and female patients with age 65 years and above scheduled for surgery, which are robust according to Fried's Modified Frailty Score.
Male and female patients with age 65 years and above scheduled for surgery, which are pre-frail according to Fried's Modified Frailty Score.
Male and female patients with age 65 years and above scheduled for surgery, which are frail according to Fried's Modified Frailty Score.
Postoperative complications
ICD-10 coded diagnoses for the hospitalization
Time frame: 06/2016-12/2022
Duration of Hospital stay
Time frame: 06/2016-12/2022
Duration of Intensive Care Unit Stay
Time frame: 06/2016-12/2022
Procedures
The procedures are measured regarding the following practices: anesthesiological, surgical, physiotherapeutic, social, cognitive, therapeutic, behavioral
Time frame: 06/2016-12/2022
Morbidity
Time frame: 06/2016-12/2022
Ventilation
Ventilation is measured in hours.
Time frame: 06/2016-12/2022
Requirements for intensive care unit
Time frame: 06/2016-12/2022
Intensive care unit scores
Time frame: 06/2016-12/2022
Disease severity
Time frame: 06/2016-12/2022
Postoperative Delirium
Delirium is measured with validated delirium scores.
Time frame: 06/2016-12/2022
Mortality
Mortality is measured in hospital.
Time frame: 06/2016-12/2022
Medical costs
Costs incurred during hospitalization
Time frame: 06/2016-12/2022
Physiotherapy
Physiotherapy is measured by Physiotherapists support.
Time frame: 06/2016-12/2022
Nutritional therapy 1
Nutritional consultations
Time frame: 06/2016-12/2022
Nutritional therapy 2
Feeding
Time frame: 06/2016-12/2022
Post - intensive care syndrome
Post - Intensive care syndrome is measured by a cluster of symptoms that are unique to the Intensive care unit environment.
Time frame: 06/2016-12/2022
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jun 2023. You cannot join it, but the record below documents what was studied.
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Charite University, Berlin, Germany →