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CompletedNCT03381716Updated Dec 22, 2017

Correlation Between Sex and Prognosis of Acute Aortic Dissection in the Chinese Population

An observational study in Acute Aortic Dissection and Sex Role, sponsored by Shenyang Northern Hospital. Completed. Open to participants aged 21 Years to 89 Years. Per ClinicalTrials.gov, last updated 2017-12-22.

Sponsored by Shenyang Northern Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
884
Ages
21 Years to 89 Years
Sex
All
01

Study summary

The study evaluated the prevalence, presentation, management, and prognosis of coronary heart disease differ according to sex.

Read the detailed description

The study included 884 patients enrolled in our institute between June 2002 and May 2016. Considering psychosocial factors, treatments, and the outcomes in men versus those in women with acute aortic dissection, explored the association of sex with psychosocial characteristics and mortality risk. Of 884 patients, 211 (23.9%) were women. The median duration of follow-up was 2.9 years (25th -75th percentiles: 1-4 years ).

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Conditions studied

  • Acute Aortic Dissection
  • Sex Role

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Keywords

  • aortic dissection
  • sex
  • treatment
03

In context

Aortic Dissection

205 studies on the registry are indexed under Aortic Dissection; 73 are open to participants now.

This study's enrollment of 884 is above the median of 230 across 115 observational studies indexed under Aortic Dissection.

Browse Aortic Dissection studies →

Lead sponsor

Shenyang Northern Hospital is the lead sponsor of 42 studies on the registry; 11 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
21 Years to 89 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Chinese

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • acute aortic dissection

Exclusion criteria

Exclusion Criteria:

  • Chronic aortic dissection
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
884 participants (actual)
Patient registry
No
Biospecimen retention
Samples without dna

Groups and cohorts

  • male

    Drug:Beta-blocker,Angiotensin II receptor blocker,Angiotensin-converting enzyme,Calcium-channel blocker,Aspirin,Statin

    Drug: drug · Procedure: Surgery

  • female

    Drug:Beta-blocker,Angiotensin II receptor blocker,Angiotensin-converting enzyme,Calcium-channel blocker,Aspirin,Statin

    Drug: drug · Procedure: Surgery

Interventions

  • Drugdrug

    Application bracket

    Also known as: thoracic endovascular aortic repair

  • ProcedureSurgery

    Surgery

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What researchers measure

Primary outcomes

  1. The outcome measure describes aortic disease-related death,aortic dissection, paraplegia, myocardial ischemia, renal insufficiency and other aortic complications.

    The study's primary endpoint during the follow up was the composite of aortic disease-related death, aortic dissection, paraplegia, myocardial ischemia, renal insufficiency and other aortic complications during follow-up.

    Time frame: 2.9years

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Bossone E, LaBounty TM, Eagle KA. Acute aortic syndromes: diagnosis and management, an update. Eur Heart J. 2018 Mar 1;39(9):739-749d. doi: 10.1093/eurheartj/ehx319. PubMed 29106452 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 22, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03381716
Lead sponsor
Shenyang Northern Hospital
Responsible party
Han Yaling, MD (Correlation between sex and prognosis of acute aortic dissection in the Chinese population, Shenyang Northern Hospital) — Principal investigator
First posted
Dec 22, 2017
Start date
Jun 19, 2002
Primary completion
May 29, 2016
Completion
May 29, 2016
Last update
Dec 22, 2017

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2017. You cannot join it, but the record below documents what was studied.

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