An observational study in Pain, sponsored by University Hospital, Grenoble. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-08-03.
Sponsored by University Hospital, Grenoble · Observational
Among 18 studies in Pain by University Hospital, Grenoble — 3 open to participants now, 3 under way, none of them phase 3. Pain · University Hospital, Grenoble.
Among the 18 studies in Pain by University Hospital, Grenoble, this one is the only one that started in 2017, is one of 4 observational ones, and was the 11th registered.
10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.
This study's enrollment of 200 is above the median of 100 across 1,252 observational studies indexed under Pain.
Browse Pain studies →3 of the 18 studies in Pain by University Hospital, Grenoble are open now, in 1 country. Each count lists the studies.
Of the 929 Pain studies recruiting now, 384 (41%) set no upper age limit and 434 (47%) stop at 75 or younger; 146 take children under 18; 222 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →18 studies; the count open now beside each. This study's row is marked.
First in 2003; this study’s year is marked. 1 started in 2017.
Median enrollment 70 across the 13 interventional studies, 50 across the 5 observational. Of the 11 that completed or were terminated, 0 (0%) have results posted.
University Hospital, Grenoble is the lead sponsor of 837 studies on the registry; 207 are open to participants now.
1 of the studies in Pain by University Hospital, Grenoble that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06735261University Hospital, GrenobleSphenopalatine Block in Headache in Patients With Non-traumatic Subarachnoid Hemorrhage | 2027-08-31 |
Among the 18 studies in Pain by University Hospital, Grenoble, from their registry updates:
The prevalence of pain in the emergency department is estimated between 60% and 78%. However, many studies reported oligo analgesia in about half of patient admitted to the emergency department. The delay before effective analgesia is one of the main causes of oligoanalgesia. The use of nurse-directed protocol allows the administration of analgesic upon admission to the emergency department. Nevertheless the need of intravenous access may delay analgesia. The use of oral form analgesics even with immediate release does not allow effective analgesia before 20 min. Pain management protocol in the emergency reception desk of CHU Grenoble Alpes (CHUGA) includes paracetamol that can be combined with oxycodone tablets depending on the pain intensity. For any mono traumatized it is possible to associate self-administer methoxyflurane inhaler. The pain management protocol is already used in the emergency reception desk of CHU Grenoble Alpes.The different analgesics( paracetamol,oral oxycodone, methoxyflurane) are already administered as part of routine care.The use of these different analgesics means would allow a rapid and adapted effectiveness to the pain intensity. However, there are no data on the efficacy and acceptability of such an early multimodal analgesia protocol in the emergency department.
200 Patients will be included from 8:00 am to 8:00 pm and will receive a multimodal analgesia under the nurse-directed pain management protocol (paracetamol +/- oral oxycodone +/- methoxyflurane) as part of routine medical care.
The pain will be evaluated (Numerical rating scale) prior to the administration and reassessed by a nurse every 5 minutes for 30 minutes and then at 45min and 1 hour after administration of the pain protocol. Satisfaction of patients and caregivers will also be assessed at the end of care.
Patient admitted at the emergency for non-multiple trauma pain
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Trauma with at least one of the following severity criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Proportion of patients with a score of less than or equal to 3 on a pain Numeric Rating scale (NRS) (0-10) 15 minutes after inclusion
NRS scale (0-10)
Time frame: 15 minutes after inclusion
Secondary efficacy criteria
Delay of pain relief defined by a 2 point reduction in the NRS scale (0-10)
Time frame: 15, 30 and 45 min (after inclusion)
Number of patient with 30% reduction in pain intensity
NRS scale (0-10)
Time frame: 15,30 and 45 min (after inclusion)
Satisfaction of caregiver and patient
Patient and caregiver satisfaction evaluated by a visual analog scale (VAS), covering the whole range of analgesic management and in particular each component of multimodal analgesia. The VAS scale ranges are : (not at all satisfied I will not take again - quite satisfied i will take again) for the patient and (not at all satisfied i will not give again - quite satisfied i will give again) for the caregiver
Time frame: 1h after inclusion
Plan to share: No
This study is completed, as verified in Aug 2018. You cannot join it, but the record below documents what was studied.
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