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Not yet recruitingNCT07864857TAILLEUpdated Oct 8, 2026

Automated and Reliable Estimation of Patient Height From CT Scan Using an Artificial Intelligence Algorithm

An observational study in Patient With an Appointment for an Abdominal CT Scan and Able to Stand up for Height Measurement, sponsored by University Hospital, Grenoble. Not yet recruiting at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-10-08.

Sponsored by University Hospital, Grenoble · Observational

Updated Oct 8, 2026Newly registeredGo to Updates ↓
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
200
Ages
18 Years and older
Sex
All
01

Study summary

The TAILLE study is a single-center, non-interventional (RIPH3), uncontrolled, non-randomized, open-label study.prospective study conducted at CHU Grenoble Alpes.

The goal is to evaluate the reliability of an AI algorithm developed as part of the TAILLE-pilot study to estimate height from abdominal CT scan data and relevant clinical data like age and gender.

The TAILLE-pilot study , is a pilot data study (RNIPH) aimed at developing artificial intelligence algorithms using a retrospective cohort, developed by our team. It is based on AI algorithms trained to predict height from abdominal CT scan volumes.

The TAILLE study therefore aims to prospectively evaluate the performance of this algorithm in a new cohort of adult patients scheduled for an abdominal CT scan. We hypothesize that height can be reliably estimated using this algorithm, potentially with greater accuracy at the individual level than self-reported height, the limitations of which have been documented in the literature.

As part of the TAILLE study, we will compare three methods of height estimation or measurement :

  • CRA-measured height: height measured by a Clinical Research Associate (CRA), serving as the reference method;
  • AI-estimated height: height estimated by the AI algorithm developed as part of the TAILLE-pilot study;
  • Self-reported height: height reported by the patient.
Read the detailed description

The TAILLE study aims to prospectively validate the AI-algorithm, hypothesizing that it provides a more reliable estimate of height than self-reported height.

02

Conditions studied

  • Patient With an Appointment for an Abdominal CT Scan and Able to Stand up for Height Measurement

Keywords

  • AI algorithm
  • Height estimation
  • sarcopenia
  • malnutrition
03

In context

Sarcopenia

1,208 studies on the registry are indexed under Sarcopenia; 402 are open to participants now.

This study's planned enrollment of 200 is above the median of 120 across 419 observational studies indexed under Sarcopenia.

Browse Sarcopenia studies →

Lead sponsor

University Hospital, Grenoble is the lead sponsor of 816 studies on the registry; 206 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patient with a scheduled appointment for an abdominal CT scan in the Radiology Department of CHUGA

Inclusion criteria

  • Patient with a scheduled appointment for an abdominal CT scan in the Radiology Department of CHUGA
  • Patient able to stand for height measurement
  • Patient who does not object to participating in the study
  • Patient affiliated with a social security

Exclusion criteria

Exclusion Criteria:

  • Patient with amputation of at least one limb
  • Patient with metallic hardware in the spine (artifact)
  • Protected person referred to in Articles L1121-5 to L1121-8 of the Code of Public Health
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
200 participants (estimated)
Target follow-up
1 Day
Patient registry
Yes

Groups and cohorts

  • Automated and Reliable Estimation of Patient Height From CT Scan

    Height and weight measured and collection of patient self-reported height and weight

06

What researchers measure

Primary outcomes

  1. Assessment of the reliability of an AI algorithm developed as part of the TAILLE-pilot study to estimate height from abdominal CT scan and relevant clinical data, such as gender and sex

    Assessment of the differences between CRA-measured height and AI-estimated height (CRA = Clinical Research Associate). CRA-measured height is the reference

    Time frame: At enrollement

Secondary outcomes

  1. Assessment the most reliable method for height estimation by comparing self-reported and AI-estimated height with CRA-measured height

    Differences between CRA-measured height and self-reported height, and between CRA-measured height and AI-estimated height

    Time frame: At enrollment

  2. Identification of factors that may influence the reliability of the AI algorithm for height estimation, particularly gender and age

    Difference between CRA-measured height and AI-estimated height according to factors that may affect the reliability of the algorithm, particularly gender and age

    Time frame: At enrollment

  3. Assessment of the impact of using self-reported height and AI-estimated height on sarcopenia risk classification

    In a hypothetical clinical context, change in sarcopenia risk category according to the SMI value calculated from the muscle area determined by the ODIASP software. Sarcopenia risk will be defined according to the thresholds established by the French National Authority for Health (HAS): men, SMI \< 52.4 cm²/m²; women, SMI \< 38.5 cm²/m²

    Time frame: At enrollment

  4. Assessment of the impact of using self-reported height and AI-estimated height on the calculation of the theoretical chemotherapy dose

    In a hypothetical clinical context, percentage of patients receiving a chemotherapy dose lower than 85% of the theoretical dose, a threshold below which impaired prognosis has been reported (Nielson et al., 2021). The dose will be calculated based on body surface area, which depends on the weight measured by the CRA and height. The analyses will focus in particular on commonly used chemotherapy regimens for gastrointestinal cancers: 5-fluorouracil 2,400 mg/m², gemcitabine 1,000 mg/m², and oxaliplatin 85 mg/m²

    Time frame: At enrollment

  5. Assessment of the impact of using self-reported height and AI-estimated height on chronic kidney disease (CKD) staging estimated using the CKD-EPI equation adjusted for body surface area

    In a hypothetical clinical context, change in CKD stage determined based on the estimated glomerular filtration rate calculated using the CKD-EPI equation adjusted for body surface area, using the same methodology as for CJS4. This endpoint will be analyzed provided that a serum creatinine value is available in the medical record

    Time frame: At enrollment

07

Study locations

1 site
  • University Hospital CHU Grenoble Alpes
    Grenoble, 38043, France
    • Béatrice GENOUX · Contact · bgenoux@chu-grenoble.fr · +33 7 77 72 91 32
    • Cécile BETRY, Professor · Principal investigator
    • Julien GHELFI, Professor · Sub investigator
08

References and documents

Individual participant data

Plan to share: Undecided

No publications or documents are linked to this record.

09

Updates

1 registry update since Sep 25, 2026
Registered
First appeared on the registry. No changes since
Oct 8, 2026
Show all 1 update
  1. Oct 8, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07864857
Lead sponsor
University Hospital, Grenoble
Responsible party
Sponsor
First posted
Oct 8, 2026
Start date
Nov 1, 2026 (estimated)
Primary completion
Apr 30, 2027 (estimated)
Completion
Dec 31, 2027 (estimated)
Last update
Oct 8, 2026

Study contacts

Cécile BETRY, Professor
Contact
cbetry@chu-grenoble.fr
4 76 76 55 09 ext. +33
Béatrice GENOUX
Contact
bgenoux@chu-grenoble.fr
Cécile BETRY, Professor
principal investigator · Unuversity Hospital CHU Grenoble Alpes

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Oct 2026. You cannot join it, but the record below documents what was studied.

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