CClinicalTrials.gg
Status unknownNCT03369860Updated Aug 10, 2018

Neuro-cognitive Bases of Joint Action

An interventional study of Interactivity of Experimental Condition in Health Behavior and Social Interaction, sponsored by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio. Status unknown at 1 site in Italy. Open to participants aged 18 Years to 35 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-08-10.

Sponsored by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Not applicable, Interventional, and Basic science

The sponsor has not verified this record recently (last verified Aug 2018), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Not applicable
Ages
18 Years to 35 Years
Sex
All
01

Study summary

The ability to interact with conspecifics is crucial in life, yet there is no consensus on the underlying cognitive and neural mechanisms beyond those associated with imitative behaviors. This project aims to define a coherent model of non-imitative (complementary) motor interactions. The investigators hypothesize that these might be substantially based on the ability to integrate one's own and a partner's action within a unitary, dual- person (dyadic), motor plan that incorporates a shared goal.

With a novel "minimally-joint" paradigm the investigators will test this hypothesis and measure with behavioral measures (i.e., reaction times) whether the supposedly automatic tendency to imitate others is modulated by the need to coordinate with a partner to achieve a shared goal.

This paradigm will be also applied during a functional MRI experiment to describe the underlying neurophysiological patterns; using dynamic causal modeling the investigators will measure how the brain regions relevant for dyadic motor control are functionally linked.

This converging experimental strategy will permit to compare competing psychological and neural models of motor interactions in healthy participants, opening new experimental avenues for studies in adult neuropsychological patients and in children with typical and atypical social development.

02

Conditions studied

  • Health Behavior
  • Social Interaction
03

Who can participate

Ages eligible
18 Years to 35 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • right handed; no contraindication to MRI

Exclusion criteria

Exclusion Criteria:

  • contraindication to MRI
04

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
50 participants (estimated)

Study arms

  • Experimental
    Healthy Subjects

    Healthy Subjects take part in the experimental manipulation

    Behavioral: Interactivity of Experimental Condition

Interventions

  • BehavioralInteractivity of Experimental Condition

    The neurofunctional correlates of motor control will be compared between a collaborative and non-interactive condition.

05

What researchers measure

Primary outcomes

  1. Reaction Times

    The investigators will compare Reaction Times of participants recorded during Joint Action with those recorded in Non-Joint individual condition.

    Time frame: 1 year

  2. BOLD activations

    The investigators will study the neurofunctional activations indexed by the Blood Oxygen Level Dependent (BOLD) recorded during Joint Action will be compared to the Non-Joint actions

    Time frame: 1 year

06

Study locations

1 of 1 sites recruiting
  • IRCCS Galeazzi Orthopedic Hospital
    Milan, 20161, Italy
    Recruiting
07

Registry details

Key details

Study ID
NCT03369860
Lead sponsor
I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Responsible party
Sponsor
First posted
Dec 12, 2017
Start date
Apr 1, 2017
Primary completion
Dec 20, 2018 (estimated)
Completion
Dec 20, 2019 (estimated)
Last update
Aug 10, 2018

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is status unknown, as verified in Aug 2018. You cannot join it, but the record below documents what was studied.

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