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CompletedNCT03369080Updated Oct 4, 2022

Prospective Survey of Body Mass Index in People With Spinal Cord Injury.

An observational study in Spinal Cord Injuries, sponsored by Rigshospitalet, Denmark. Completed at 1 site in Denmark. Open to participants aged 1 Year to 100 Years. Per ClinicalTrials.gov, last updated 2022-10-04.

Sponsored by Rigshospitalet, Denmark · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
98
Ages
1 Year to 100 Years
Sex
All
01

Study summary

This study is a prospective national survey of body mass index, and includes all patients with a new spinal cord injury hospitalized at Clinic for Spinal Cord Injuries, Rigshospitalet and Spinal Cord Injury Center of Western Denmark during a period of 9 months. Informed consent is retrieved from all participants.

Read the detailed description

The current study is a sub- study in a Ph.D project containing 4 sub- studies. The protocol for the current study includes all four sub- studies, and each of the other three sub- studies will be registered ongoing individually. The current study is a prospective national survey of body mass index (BMI), and includes all patients with a new spinal cord injury hospitalized at Clinic for Spinal Cord Injuries, Rigshospitalet (CSCI) and Spinal Cord Injury Center of Western Denmark during a period of 9 months whereby 100 patients are expected to participate. Data are collected at admission and discharge. At CSCI BMI is collected every 6 weeks and all outcome measures will also be collected at follow up 6 months after discharge. A VO2peak test at discharge is performed as well, and in some participants accelerometry is performed in order to describe the amount and intensity of physical activity. Test- retest reliability of the VO2peak test and accelerometry is investigated as well. Patients with a new Spinal Cord Injury within the last 12 months, who are admitted for rehabilitation several months after the time of injury are also included in the prospective survey. Therefore the data for BMI at the time of injury is collected for all patients at admission to primary rehabilitation from both the patient journal and also by asking the patient about weight and height at the time of injury

02

Conditions studied

  • Spinal Cord Injuries

Keywords

  • Body Mass Index
03

Who can participate

Ages eligible
1 Year to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All newly injured patients with Spinal Cord Injury admitted at Clinic for Spinal Cord Injuries, Rigshospitalet and Spinal Cord Injury Centre of Western Denmark

Inclusion criteria

  • All newly injured patients with Spinal Cord Injury (within the last 12 months)admitted at Clinic for Spinal Cord Injuries, Rigshospitalet and Spinal Cord Injury Centre of Western Denmark, are included regardless of age, neurological level of lesion and completeness of the injury if informed consent is retrieved.

Exclusion criteria

Exclusion Criteria:

  • Insufficient skills in Danish language
  • Reduced mental function that prevents reading and answering the questionnaires
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
98 participants (actual)
Patient registry
No

Groups and cohorts

  • Danish National Cohort

    This study includes all patients with a new Spinal Cord Injury hospitalized at Clinic for Spinal Cord Injuries, Rigshospitalet or Spinal Cord Injury Center of Western Denmark

05

What researchers measure

Primary outcomes

  1. Change in Body Mass Index

    Defined as a person's weight in kilograms divided by the square of the person's height in metres (kg/m2

    Time frame: Change from baseline to follow-up 6 months after discharge from primary rehabilitation

Other outcomes

  1. International Standards for Neurological Classification of Spinal Cord Injury

    The classification tool involves a sensory and motor examination to determine the neurological level of the injury and whether the injury is complete or incomplete. The International Standards for Neurological Classification of Spinal Cord Injury defines neurological level as the most caudal level at which sensory and motor function are intact. The completeness of the injury is graded according to the American Spinal Injury Association Impairment Scale

    Time frame: At admission

  2. International Standards for Neurological Classification of Spinal Cord Injury

    The classification tool involves a sensory and motor examination to determine the neurological level of the injury and whether the injury is complete or incomplete. TheInternational Standards for Neurological Classification of Spinal Cord Injury defines neurological level as the most caudal level at which sensory and motor function are intact. The completeness of the injury is graded according to the American Spinal Injury Association Impairment Scale

    Time frame: At discharge in average 4-6 months after admission to primary rehabilitation

  3. International Standards for Neurological Classification of Spinal Cord Injury

    The classification tool involves a sensory and motor examination to determine the neurological level of the injury and whether the injury is complete or incomplete. The International Standards for Neurological Classification of Spinal Cord Injury defines neurological level as the most caudal level at which sensory and motor function are intact. The completeness of the injury is graded according to the American Spinal Injury Associationment Impairment Scale

    Time frame: At follow up 6 months after discharge

  4. Spinal Cord Injury Independence Measure III

    The Spinal Cord Injury Independence Measure III is composed of 19 items that assess 3 domains.1 Self-care (6 items, scores range from 0-20). 2 Respiration and sphincter management (4 items, scores range from 0-40). 3 Mobility (9 items, scores range from 0-40). The total SCIM scores range from 0 to 100.

    Time frame: At admission

  5. Spinal Cord Injury Independence Measure III

    The Spinal Cord Injury Independence Measure III is composed of 19 items that assess 3 domains.1 Self-care (6 items, scores range from 0-20). 2 Respiration and sphincter management (4 items, scores range from 0-40). 3 Mobility (9 items, scores range from 0-40). The total SCIM scores range from 0 to 100.

    Time frame: At discharge in average 4-6 months after admission to primary rehabilitation

  6. Spinal Cord Injury Independence Measure III

    The Spinal Cord Injury Independence Measure III is composed of 19 items that assess 3 domains.1 Self-care (6 items, scores range from 0-20). 2 Respiration and sphincter management (4 items, scores range from 0-40). 3 Mobility (9 items, scores range from 0-40). The total SCIM scores range from 0 to 100.

    Time frame: At follow up 6 months after discharge

  7. Patient Health Questionnaire- 2

    The Patient Health Questionnaire- 2 comprising the first 2 items of the PHQ-9, inquires about the degree to which an individual has experienced depressed mood and anhedonia over the past two weeks Score range is from from 0- 3, with 0 indicating a better score. Total score ranges from 0 (minimum score to 6 (maximum score), with 0 indicating a better score and with a cut-off score of 3 as the cut point for screening purposes.

    Time frame: At admission

  8. Patient Health Questionnaire- 2

    Patient Health Questionnaire- 2 comprising the first 2 items of the PHQ-9, inquires about the degree to which an individual has experienced depressed mood and anhedonia over the past two weeks Score range is from from 0- 3, with 0 indicating a better score. Total score ranges from 0 (minimum score to 6 (maximum score), with 0 indicating a better score and with a cut-off score of 3 as the cut point for screening purposes.

    Time frame: At discharge in average 4- 6 months after admission to primary rehabilitation

  9. Patient Health Questionnaire- 2

    The Patient Health Questionnaire- 2 comprising the first 2 items of the PHQ-9, inquires about the degree to which an individual has experienced depressed mood and anhedonia over the past two weeks Score range is from from 0- 3, with 0 indicating a better score. Total score ranges from 0 (minimum score to 6 (maximum score), with 0 indicating a better score and with a cut-off score of 3 as the cut point for screening purposes.

    Time frame: At follow up 6 months after discharge

  10. The International SCI Quality of Life Basic Data Set

    Consists of three questions scored on a scale of 0-10 regarding general quality of life, physical health and satisfaction with psychological health

    Time frame: At admission

  11. The International SCI Quality of Life Basic Data Set

    Consists of three questions scored on a scale of 0-10 regarding general quality of life, physical health and satisfaction with psychological health

    Time frame: At discharge in average 4- 6 months after admission to primary rehabilitation

  12. The International SCI Quality of Life Basic Data Set

    Consists of three questions scored on a scale of 0-10 regarding general quality of life, physical health and satisfaction with psychological health

    Time frame: At follow up 6 months after discharge

  13. Leisure Time Physical Activity Questionnaire for people with Spinal Cord Injury (

    Questionnaire concerning the amount of leisure time physical activity the past 7 days. The patient describes how many of the last 7 days and for how many minutes he/she has been physical active and also the intensity of the activity described as mild, moderate or vigorous. Higher values related to days, minutes and intensity represent a better outcome and lower values represent a worse outcome.On the scale related to days, 0 is a minimum score and 7 is a maximum score.

    Time frame: At admission

  14. Leisure Time Physical Activity Questionnaire for people with Spinal Cord Injury (

    Questionnaire concerning the amount of leisure time physical activity the past 7 days. The patient describes how many of the last 7 days and for how many minutes he/she has been physical active and also the intensity of the activity described as mild, moderate or vigorous. Higher values related to days, minutes and intensity represent a better outcome and lower values represent a worse outcome.On the scale related to days, 0 is a minimum score and 7 is a maximum score.

    Time frame: At discharge in average 4-6 months after admission to primary rehabilitation

  15. Leisure Time Physical Activity Questionnaire for people with Spinal Cord Injury (

    Questionnaire concerning the amount of leisure time physical activity the past 7 days. The patient describes how many of the last 7 days and for how many minutes he/she has been physical active and also the intensity of the activity described as mild, moderate or vigorous. Higher values related to days, minutes and intensity represent a better outcome and lower values represent a worse outcome.On the scale related to days, 0 is a minimum score and 7 is a maximum score.

    Time frame: At follow up 6 months after discharge

  16. The Exercise Self Efficacy Scale for people with Spinal Cord Injury

    A questionnaire with a 4-point rating scale describing how confident persons with spinal cord injury are with regard to carrying out regular physical activities and exercise. The questionnaire consists of 10 items with corresponding response options on a 4-point Likert scale (1-not at all true, 4-always true) with 1 indicating a worse score and 4 indicating a better score. The total score is derived by summing the scores for the individual items with a possible score range from 10 to 40.

    Time frame: At admission

  17. The Exercise Self Efficacy Scale for people with Spinal Cord Injury

    A questionnaire with a 4-point rating scale describing how confident persons with spinal cord injury are with regard to carrying out regular physical activities and exercise. The questionnaire consists of 10 items with corresponding response options on a 4-point Likert scale (1-not at all true, 4-always true) with 1 indicating a worse score and 4 indicating a better score. The total score is derived by summing the scores for the individual items with a possible score range from 10 to 40.

    Time frame: At discharge in average 4-6 months after admission to primary rehabilitation

  18. The Exercise Self Efficacy Scale for people with Spinal Cord Injury

    A questionnaire with a 4-point rating scale describing how confident persons with spinal cord injury are with regard to carrying out regular physical activities and exercise. The questionnaire consists of 10 items with corresponding response options on a 4-point Likert scale (1-not at all true, 4-always true) with 1 indicating a worse score and 4 indicating a better score. The total score is derived by summing the scores for the individual items with a possible score range from 10 to 40.

    Time frame: At follow up 6 months after discharge

  19. VO2peak

    Measures the maximal oxygen consumption in ml/kg/min

    Time frame: At discharge in average 4- 6 months after admission to primary rehabilitation

  20. Objective physical activity (accelerometry)

    Is measured with a multisensor device recording accelerations and heart rate.

    Time frame: At discharge in average 4- 6 months after admission to primary rehabilitation

06

Study locations

1 site
  • Clinic for Spinal Cord Injuries, Rigshopitalet
    Hornbæk, 3100, Denmark
07

References and documents

Publications

  • Holm NJ, Moller T, Adamsen L, Dalsgaard LT, Biering-Sorensen F, Schou LH. Health promotion and cardiovascular risk reduction in people with spinal cord injury: physical activity, healthy diet and maintenance after discharge- protocol for a prospective national cohort study and a preintervention- postintervention study. BMJ Open. 2019 Dec 31;9(12):e030310. doi: 10.1136/bmjopen-2019-030310. PubMed 31892644 ↗

Study documents

  • Study protocol · Dec 4, 2017

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

08

Registry details

Key details

Study ID
NCT03369080
Lead sponsor
Rigshospitalet, Denmark
Collaborators
Metropolitan University College, Spinal Cord Injury Centre of Western Denmark
Responsible party
Nicolaj Jersild Holm (Ph.D student, Rigshospitalet, Denmark) — Principal investigator
First posted
Dec 11, 2017
Start date
Nov 3, 2017
Primary completion
May 31, 2019
Completion
May 31, 2019
Last update
Oct 4, 2022

Study contacts

Nicolaj J Holm, Ph.D student
principal investigator · Rigshopitalet, Clinic for Spinal Cord Injuries

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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