An interventional study of minimally invasive method and open reduction method in Pilon Fractures, Fractures and Bone, sponsored by University Hospital, Clermont-Ferrand. Terminated at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-08-05.
Sponsored by University Hospital, Clermont-Ferrand · Not applicable, Interventional, and Treatment
Among 56 studies in Fractures, Bone with a site in France — 10 open to participants now, 13 under way, none of them phase 3. Fractures, Bone · France.
Among the 56 studies in Fractures, Bone with a site in France, this one is the 26th largest by enrollment of the 28 interventional ones, is one of 2 that started in 2017, is one of 19 with no phase, and was the 23rd registered.
723 studies on the registry are indexed under Fractures, Bone; 114 are open to participants now.
This study's enrollment of 54 is below the median of 80 across 458 interventional studies indexed under Fractures, Bone.
Browse Fractures, Bone studies →10 of the 56 studies in Fractures, Bone with a site in France are open now, in 12 countries. Each count lists the studies.
Of the 70 Fractures, Bone studies recruiting now, 35 (50%) set no upper age limit and 21 (30%) stop at 75 or younger; 17 take children under 18; 14 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →56 studies; the count open now beside each. This study's row is marked.
First in 1994; this study’s year is marked. 2 started in 2017.
Median enrollment 130 across the 28 interventional studies, 140 across the 28 observational. Of the 36 that completed or were terminated, 4 (11%) have results posted.
17 of 56 have an industry lead sponsor. The 10 most frequent:
University Hospital, Clermont-Ferrand is the lead sponsor of 859 studies on the registry; 179 are open to participants now.
University Hospital, Clermont-Ferrand has 3 studies filed under Fractures, Bone — fewer than ten, so there is no comparison to draw.
1 of the studies in Fractures, Bone with a site in France that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07301749Amber Implants B.V.A Clinical Study Evaluating the Safety and Efficacy of the VCFix Spinal System for Treatment of Vertebral Compression Fractures | 2027-07-31 |
Among the 56 studies in Fractures, Bone with a site in France, from their registry updates:
The assessment consists in comparing the osteosynthesis plate with minimally invasive technique versus open reduction and internal fixation.
The aim of study is to compare (period of bandage, efficacy, safety), these two types of surgical technique by using a prospective, randomized analysis.
Several surgical techniques exist and among plate osteosynthesis, there is a minimally invasive method and the open reduction method.
Investigators think that the minimally invasive method with intern plate is more efficient than the open reduction method.
These techniques may better preserve perifracture soft tissues, hematoma. It may lead to a smaller muscle detachment.
The minimally invasive technique allows a more efficient vascularization of the fracture site, what would increase bone healing and the functional prognosis of tibial pilon lesions.
It's all these issues investigators would like to assess with a randomized study.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
The patients are treated with minimally invasive method
Procedure: minimally invasive method
The patients are treated with open reduction method
Procedure: open reduction method
type of surgical technique
type of surgical technique
Healing
Measure of the duration of the bandage with index form of follow-up the state cutaneous of the wound. This measure was a number.
Time frame: at 45 days
AOFAS clinical score
American Orthopedic Foot and Ankle Society was a standard method of reporting clinical status of the ankle and foot. The systems incorporate both subjective and objective factors into numerical scales to describe function, alignment, and pain. The score varies between 0 and 100, more the value is better brought up is the score
Time frame: pre op, 45 days, 3, 6 and 12 months
Nach mazur and al score
The Nach mazur grading system uses 100 points to assess pain, function while wearing shoes and the range of ankle movement. The maximum score a patient with a solid ankle fusion.
Time frame: pre op 45 days, 3, 6 and 12 months
The Foot & Ankle Disability Index
The Foot and Ankle Disability Index (FADI) was designed to assess functional limitations related to foot and ankle conditions. Subjective reports of function are classified as generic or specific measures, which include condition-specific, population-specific, and patient-specific instruments. The FADI have a total point value of 100 points, more the value is better brought up is the score
Time frame: pre op 45 days, 3, 6 and 12 months
Pain
THE VISUAL SIMILAR SCALE is auto-completed. For the intensity of pain, the scale varies between " no pain " (the score of 0) and " the pain so badly as he could be " or " the worst conceivable pain " (the score of 10)
Time frame: pre op 45 days, 3, 6 and 12 months
Complications
list of the complications
Time frame: pre op 45 days, 3, 6 and 12 months
Radiologic evaluation
Radiologic evaluation
Time frame: pre op 45 days, 3, 6 and 12 months
Ran from Nov 2017 to primary completion in Apr 2024, 77 months.
How these figures are worked out, and which studies are left out of them.
This study is terminated, as verified in Aug 2026. You cannot join it, but the record below documents what was studied.
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University Hospital, Clermont-Ferrand →