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CompletedNCT03365570Updated Jan 30, 2019

Prevalence of Oral Manifestations of Iron Deficiency Anemia in a Sample of Egyptian Population

An observational study in Iron Deficiency Anemia, sponsored by Cairo University. Completed at 1 site in Egypt. Open to participants aged Up to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-01-30.

Sponsored by Cairo University · Observational

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Study type
Observational
Model
Ecologic or community
Time perspective
Cross-sectional
Enrollment
180
Ages
Up to 70 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 11 studies in Anemia, Iron-Deficiency by Cairo University — 4 open to participants now, 4 under way, none of them phase 3. Anemia, Iron-Deficiency · Cairo University.

Started
2018
with 1 other
Observational
3 of 11
1 open now
Registered
2nd of 11
by date

Among the 11 studies in Anemia, Iron-Deficiency by Cairo University, this one is one of 2 that started in 2018, is one of 3 observational ones, and was the 2nd registered.

Anemia, Iron-Deficiency

601 studies on the registry are indexed under Anemia, Iron-Deficiency; 96 are open to participants now.

Browse Anemia, Iron-Deficiency studies →

Open to participants now

4 of the 11 studies in Anemia, Iron-Deficiency by Cairo University are open now, in 2 countries. Recruiting first, the newest first:

By country, each count listing its studies:

All 4 open studies →

Where they have run

Who these studies take

Of the 55 Anemia, Iron-Deficiency studies recruiting now, 19 (35%) set no upper age limit and 32 (58%) stop at 75 or younger; 16 take children under 18; 17 take healthy volunteers.

This study: Up to 70 Years · all sexes · healthy volunteers too.

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Watch this landscapeDownload CSVNarrow it in search →With an account: a weekly mail of what changed among 11 studies in Anemia, Iron-Deficiency by Cairo University, or all of them as a file.
02

Study summary

According to WHO Reportin 2002, iron deficiency anemia was considered to be the most important contributing factor to the global burden of anemia. Children and women in reproductive ages are more at risk factor for developing iron deficiency anemia.No previous study has been held to assess prevalence of oral manifestations of iron deficiency anemia as a hospital-based cross-sectional study on a sample of Egyptian patients in hematology department (no previous data recorded).

Read the detailed description

Study will be held in at the Hematology department at El Qasr Al-Einy Cairo University Hospital data collection started from February 2018 till end of April 2018 primary completion.

Clinical examination performed for oral mucosa, the number and type of lesions will be recorded. Patients' age, sex, duration of illness, type of anemia, location of any oral lesion or abnormality, history of drug and alcohol consumption, and presence or absence of dentures, will be recorded participants will not followed up and data will be collected prospectively.

A copy of participant's blood record will be obtained from the hematology department upon its approval.

Participants:

Egyptian patients diagnosed with Iron deficiency anemia that attending the Hematology department at El Qasr Al-Einy Cairo University Hospital will be enrolled in the study. The age of participant enroll will be up to 70 years old, males and females will be included.

For each eligible participant, a full history will be obtained according to an assessment sheet, followed by clinical examination which will be done through an interview between the investigator and the patient.

All participants will be asked to sign a study-related informed consent. Oral manifestations of these patients will be evaluated by an oral medicine master student (the investigator).

03

Conditions studied

  • Iron Deficiency Anemia

Keywords

  • hemoglobin, iron, oral lesions, oral manifestations,cross-sectional study
04

Who can participate

Ages eligible
Up to 70 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

Participants:

Egyptian patients diagnosed with Iron deficiency anemia that attending the Hematology department at El Qasr Al-Einy Cairo University Hospital will be enrolled in the study. The age of participant enroll will be up to 70 years old, males and females will be included.

For each eligible participant, a full history will be obtained according to an assessment sheet, followed by clinical examination which will be done through an interview between the investigator and the patient.

All participants will be asked to sign a study-related informed consent.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Patients diagnosed with iron deficiency anemia based on their blood tests.
  2. Age: by maximum 70 years old.
  3. Males and females will be included.

Exclusion criteria

Exclusion Criteria

  1. Patients suffering from any other systemic diseases known to influence oral and maxillofacial manifestations will be excluded.
  2. Patients suffering from any other systemic diseases known to cause IDA as secondary condition will be excluded.
  3. Patients on drug therapy that may have oral mucosal manifestations.
  4. Lesions appear because of existing local factors for example traumatic ulcer on the tongue because of sharp tooth against tongue, angular cheilitis because of poor denture design and older age patients.
  5. Inflammatory diseases, , or recent surgery were excluded.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Cancer (malignancy)

Malignancy means cancer. Criteria about another or earlier malignancy ask whether you have had a different cancer, usually within a set number of years.

Some are commonly allowed, such as treated skin cancers other than melanoma and early cancers removed completely — check the exceptions this study lists.

05

Study design

Observational model
Ecologic or community
Time perspective
Cross-sectional
Enrollment
180 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Prevalence of oral mucosal lesions

    Presence of oral mucosal lesions will be assessed by clinical picture into dichotomous outcome (Yes/No) and percentage of each.

    Time frame: 15 minutes

07

Study locations

1 site
  • Cairo University
    Cairo, 12613, Egypt
08

References and documents

Publications

  • DeLoughery TG. Iron Deficiency Anemia. Med Clin North Am. 2017 Mar;101(2):319-332. doi: 10.1016/j.mcna.2016.09.004. Epub 2016 Dec 8. PubMed 28189173 ↗
  • Rohani B. Oral manifestations and blood profile in patients with iron deficiency anemia. J Formos Med Assoc. 2015 Jan;114(1):97. doi: 10.1016/j.jfma.2014.07.004. Epub 2014 Aug 10. No abstract available. PubMed 25115528 ↗
  • Wu YC, Wang YP, Chang JY, Cheng SJ, Chen HM, Sun A. Oral manifestations and blood profile in patients with iron deficiency anemia. J Formos Med Assoc. 2014 Feb;113(2):83-7. doi: 10.1016/j.jfma.2013.11.010. Epub 2013 Dec 30. PubMed 24388269 ↗

Individual participant data

Plan to share: No

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Ran from May 2018 to primary completion in Nov 2018, 6 months.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 2, 2017
First posted
Dec 7, 2017
StartActual
May 1, 2018
Primary completionActual
Nov 1, 2018
CompletionActual
Nov 9, 2018
Last update
Jan 30, 2019
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jan 30, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03365570
Lead sponsor
Cairo University
Responsible party
Eman Mohamed Abdallah Alsheikh (BDS, Master student at oral medicine department, Cairo University) — Principal investigator
First posted
Dec 7, 2017
Start date
May 1, 2018
Primary completion
Nov 1, 2018
Completion
Nov 9, 2018
Last update
Jan 30, 2019

Study contacts

Fatheya Zahran, Professor
study chair · Head of the Department of Oral Medicine and periodontology Cairo University
Eman Alsheikh
principal investigator · Master student
Eman Mo Amr, A.Professor
study director · associate professor in the Department of Oral Medicine and periodontology Cairo University

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.

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