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CompletedNCT03357211POMOCOBSUpdated Dec 2, 2017

Accuracy of Maxillary Repositioning During Orthognathic Surgery

An observational study in Orthognathic Surgery and Maxillofacial Abnormalities, sponsored by Centre Hospitalier Annecy Genevois. Completed. Open to participants aged 16 Years and older. Per ClinicalTrials.gov, last updated 2017-12-02.

Sponsored by Centre Hospitalier Annecy Genevois · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
30
Ages
16 Years and older
Sex
All
01

Study summary

Orthognathic surgery aims to correct jaw position taking into account esthetic and functional criteria (dental occlusion, lip position, breathing...). These surgeries are planned using clinical, radiological and dental cast data. The result of this planning are occlusal splints. Orthognathic surgery had improved in the last decade with 3 dimensions computerized tomography scan (3D CT-Scan) planning and osteosynthesis implants. However the accuracy of the operative results compared to the planned ones has rarely been measured.

Read the detailed description

Orthognathic surgery aims to correct jaw position taking into account esthetic and functional criteria (dental occlusion, lip position, breathing...). These surgeries are planned only after the end of the growing period and in association with orthodontics. It is necessary to wait the end of facial growth to expect a stable result especially concerning mandibular. The age limit seems to be around 15 to 16 years old for retromandibular deformities and around 18 years old for premandibular deformities.

These surgeries are planned using clinical, radiological and dental cast data. Occlusal splints are made using all these results; these occlusal splints are used during the orthognathic surgery to maintain bones in the planned position.

Since 1993, a navigation system (Orthopilot™) is used, which allow to track jaw position, in real time, with an accuracy around one millimeter and one degree, during orthognathic surgery. This system is routinely used for condyle repositioning after mandibular sagittal split osteotomies; but it is also useful for maxillary navigation and positioning.

The investigator propose to measure the accuracy of the operative results compared to the planned ones, using the Orthopilot™ system.

02

Conditions studied

  • Orthognathic Surgery
  • Maxillofacial Abnormalities
03

Who can participate

Ages eligible
16 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

patients needing orthognathic surgery with monobloc mobilization of the maxilla via a Le Fort I osteotomy alone or associated to a mandibular osteotomy, whatever the indication (malocclusion, sleep apnea, temporomandibular dysfunction...), who are adressed to the principal investigator

Inclusion criteria

  • patients needing orthognathic surgery with mobilization of the maxilla via a Le Fort I osteotomy, alone or associated to a mandibular osteotomy, whatever the indication (poor occlusion, sleep apnea, temporo-mandibular dysfunction...)
  • patient over 16 years old
  • having not expressed any opposition to the collection of his/her personal data for this study (patient him/herself or holder of parental authority in case of patients younger than 18)

Exclusion criteria

Exclusion Criteria:

  • pregnancy
  • patients deprived of liberty
  • protected adult
  • patients needing maxillary disjunction
04

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
30 participants (actual)
Patient registry
No
05

What researchers measure

Primary outcomes

  1. Distribution of the translational and rotational shifts of the maxilla between planning and realization

    Shifts will be quantified by 6 components (3 in rotation and 3 in translation) in a coordinate system given by Orthopilot™ navigation system. Accuracy of the surgical technic is evaluated by the distribution of the translational and rotational shifts of the maxilla between planning and realization, taking account conformity (when left/right translation is ≤ 1 mm, top/bottom and back/front translations are \< 2 mm, frontal rotation is ≤ 1° and axial and sagittal rotations are ≤ 2°), failure (when left/right, top/bottom and back/front translations are \> 2 mm, frontal, axial and sagittal rotations are \>4°), and non conformity (every other shifts).

    Time frame: during the surgery

Secondary outcomes

  1. Inter-incisal vector

    The inter-incisal vector (that is square root of the sum of each translation shift squared) is calculated by the statistician. It derived from shifts in millimeter and degree measured during surgery by Orthopilot™ navigation system.

    Time frame: during the surgery

06

Study locations

No study locations are listed for this record.

07

Registry details

Key details

Study ID
NCT03357211
Lead sponsor
Centre Hospitalier Annecy Genevois
Responsible party
Sponsor
First posted
Nov 29, 2017
Start date
Feb 29, 2016
Primary completion
Jun 1, 2017
Completion
Jun 1, 2017
Last update
Dec 2, 2017

Study contacts

Georges Bettega, MD/PhD
principal investigator · CH Annecy Genevois

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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