An observational study in Hip Fractures, sponsored by University Hospital, Montpellier. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2018-07-19.
Sponsored by University Hospital, Montpellier · Observational
Hip fracture surgery requires high risk anesthetic procedure for elderly patients (1). General anesthesia, continuous spinal anesthesia and peripheral nerve blocks are three anesthetic techniques possible. Continuous spinal anesthesia has proven its efficacity to provide an intraoperative haemodynamic stability wich guarantees good patients outcomes (2), in comparison with general anesthesia but there is poor evidence in the literature concerning the use of peripheral nerve blocks.
The primary objective of this study was to compare intraoperative haemodynamic stability provides by peripheral nerve block versus general anesthesia and continuous spinal anesthesia.
Secondary outcomes included : use of vasoactive drugs, opioids consumption, lengh of stay and inhospital mortality.
After receiving the ethic approval from the "CERAR", the investigators retrospectively identified all patients who underwent hip fracture surgery from January 1 2015, to December 31, 2016 in the CHU of Montpellier. The exclusion criteria were: multiple trauma victims, two hip fractures in the same patient and single shot spinal anesthesia. In our institution the investigators used to perform three types of anesthesia: general anesthesia (GA), continuous spinal anesthesia (CSA) and combined plexus blocks (CPB). The investigators therefore made three groups GA, CSA and CPB and used a propensity score to make these groups comparable. The matching criteria were age, arterial hypertension, ASA status, Frailty score, chronic cardiac failure and type of surgery.
All adults patients operated for hip fracture between 1 January 2015 and 31 December 2016.
Exclusion criteria:
Patient who had surgery for femoral neck fracture from January 2014 to December 2016 and had general anesthesia
Other: no intervention
Patient who had surgery for femoral neck fracture from January 2014 to December 2016 and had continued spinal anesthesia
Other: no intervention
Patient who had surgery for femoral neck fracture from January 2014 to December 2016 and had peripheral nerve blocks
Other: no intervention
Observational study
Intraoperative hypotension
Decrease of at least 30% of mean arterial pressure
Time frame: 1 day
measure the total consumption of the vasopressive molecules
measure the total consumption of the vasopressive molecules (necessary when the voltage drops by more than 30% compared to the average reference voltage) : Use of vasoactive drugs
Time frame: 1 day
Length of stay
Length of stay
Time frame: 1 day
compare the use of emergency antalgics
compare the use of emergency antalgics : opioids consumption
Time frame: 1 day
Inhospital mortality
Inhospital mortality
Time frame: 1 day
No study locations are listed for this record.
Plan to share: Undecided — NC
This study is completed, as verified in Oct 2017. You cannot join it, but the record below documents what was studied.
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University Hospital, Montpellier