An observational study in Obesity, Metabolically Benign, sponsored by Alexandru Florin Rogobete. Completed. Open to participants aged 4 Years to 18 Years. Per ClinicalTrials.gov, last updated 2017-11-28.
Sponsored by Alexandru Florin Rogobete · Observational
Obesity is a chronic inflammatory disorder in which leptin, adiponectin and C reactive protein (CRP) play an important role. This study aimed to investigate the relationship between markers of adiposity like leptin, adiponectin and high sensitive C reactive protein (hsCRP) in obese children, and to determine whether these adipokines are significant markers in defining metabolic syndrome in pediatric population
The idea that adipose tissue is just a form of energy storage has changed dramatically in recent years. Currently, adipose tissue is considered to be a true endocrine gland that fulfills multiple roles in regulating different biological functions. Communication between adipose tissue and the rest of the systems is accomplished through bioactive mediators (adipokines) Adipokines control energy homeostasis and are involved in metabolic, endocrine and immunological processes.This study aimed to investigate the relationship between markers of adiposity like leptin, adiponectin and high sensitive C reactive protein (hsCRP) in obese children, and to determine whether these adipokines are significant markers in defining metabolic syndrome in pediatric population.The current retrospective observational study was conducted at the "Louis Turcanu" Emergency Hospital Timisoara over a period of one year, from July 2013 and June 2014. All inborn patient files were analyzed as anonymised limited data sets from archived records of the Endocrinology, Diabetology and Cardiology department.
27 studies on the registry are indexed under Obesity, Metabolically Benign; 8 are open to participants now.
This study's enrollment of 122 is close to the median of 134 across 10 observational studies indexed under Obesity, Metabolically Benign.
Browse Obesity, Metabolically Benign studies →This is the only study on the registry with Alexandru Florin Rogobete as lead sponsor.
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All children admitted to the Endocrinology, Diabetology and Cardiology Department who met the Inclusion Criteria
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
BMI (body mass index)
Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.
What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Obese group with metabolic syndrome/Data processing from Patient Medical Files
Other: MetS+
Obese group without metabolic syndrome/Data processing from Patient Medical Files
Other: MetS-
Data processing from Patient Medical Files
Data processing from Patient Medical Files
Defining obesity in the pediatric population
Measuring weight in kilograms and height in meters in order to calculate BMI and represent it on the percentile graph.
Time frame: Weight and height were measured on day 1 of admission. Obesity was defined as a BMI > the 95th percentile.
Leptin changes in the obese children with metabolic syndrome
Evaluating leptin in the obese group with metabolic syndrome
Time frame: Leptin levels were measured on day 1 of admission. Normal range was considered < 24ng/ml.
Adiponectin changes in the obese children with metabolic syndrome
Evaluating adiponectin in the obese group with metabolic syndrome
Time frame: Adiponectin levels were measured on day 1 of admittance in children aged between 4 and18 years. Levels 4-26 mcg/ml were defined as normal values.
Assessing cardiovascular risk in the obese children with metabolic syndrome
Evaluating hsCRP in the obese group with metabolic syndrome
Time frame: hsCRP levels were measured on day 1 of admittance in children aged between 4 and 18 years. Normal levels were considered between 0.1-2.8 mg/l
No study locations are listed for this record.
Plan to share: No
Ran from Mar 2016 to primary completion in Aug 2017, 17 months.
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This study is completed, as verified in Nov 2017. You cannot join it, but the record below documents what was studied.
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Obesity, Metabolically Benign →