An interventional study of aerobic exercise and Placebo controlled group in Bipolar Disorder and Cognitive Symptom, sponsored by Guangzhou Psychiatric Hospital. Status unknown at 1 site in China. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-11-27.
Sponsored by Guangzhou Psychiatric Hospital · Not applicable, Interventional, and Treatment
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Among 78 studies in Bipolar Disorder with a site in China — 31 open to participants now, 31 under way, 1 of them phase 3. Bipolar Disorder · China.
Among the 78 studies in Bipolar Disorder with a site in China, this one is the 17th largest by planned enrollment of the 50 interventional ones that give a count, is one of 4 that started in 2017, is one of 30 with no phase, and was the 26th registered.
1,684 studies on the registry are indexed under Bipolar Disorder; 267 are open to participants now.
Browse Bipolar Disorder studies →31 of the 78 studies in Bipolar Disorder with a site in China are open now. Recruiting first, the newest first:
Second Affiliated Hospital, Zhejiang University, School of Medicine · Sites in China
Ages 12–55 · Healthy volunteers
First Affiliated Hospital of Zhejiang University · Sites in China
Ages 18–45
Shanghai Mental Health Center · Sites in China
Ages 18–64 · Healthy volunteers
Eli Lilly and Company · Sites in China, United States, Argentina and 5 more countries
Ages 18–75
Second Affiliated Hospital, School of Medicine, Zhejiang University · Sites in China
Ages 18–45 · Women only · Healthy volunteers
A study can be open while its sites in China have not opened yet or have stopped. Only those recruiting at a site in China →
Of the 205 Bipolar Disorder studies recruiting now, 59 (29%) set no upper age limit and 134 (65%) stop at 75 or younger; 37 take children under 18; 50 take healthy volunteers.
This study: 18 Years to 60 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
78 studies; the count open now beside each. This study's row is marked.
First in 2003; this study’s year is marked. 4 started in 2017.
By drug class, each counting the studies that test any of its medicines:
This study's planned enrollment of 210 is above the median of 64 across 1,279 interventional studies indexed under Bipolar Disorder.
Median enrollment 126 across the 50 interventional studies, 560 across the 28 observational. Of the 26 that completed or were terminated, 6 (23%) have results posted.
This tab as a report to print or save as PDF → With an account.
12 of 78 have an industry lead sponsor. The 10 most frequent:
Guangzhou Psychiatric Hospital is the lead sponsor of 13 studies on the registry; 2 are open to participants now.
Guangzhou Psychiatric Hospital has 3 studies filed under Bipolar Disorder — fewer than ten, so there is no comparison to draw.
10 of the studies in Bipolar Disorder with a site in China that are under way reach primary completion within a year, 1 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07140913Phase 3Bristol-Myers SquibbA Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine | 2027-06-28 |
| NCT07021508First Affiliated Hospital of Zhejiang UniversityEfficacy and Safety Assessment of Temporal Interference Stimulation to Improve Bipolar Depression | 2026-12 |
| NCT07589647First Affiliated Hospital of Zhejiang UniversityResearch on the Efficacy and Safety of Targeted Suprachiasmatic Nucleus Electrical Stimulation for Improving Metabolic Disorders in Patients With Stable Bipolar Disorder Comorbid With Obesity | 2026-12-31 |
| NCT06831435Peking UniversityEffectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression: a Real-world Study | 2026-12-31 |
| NCT05480150First Affiliated Hospital of Zhejiang UniversityChinese Longitudinal and Systematic Study of Bioplar Disorder | 2026-12-31 |
Add all 10 to your calendar (.ics) → With an account.
Among the 78 studies in Bipolar Disorder with a site in China, from their registry updates:
This tab as a report to print or save as PDF → With an account.
This study will investigate the effects of aerobic exercise on mental states, cognition, BDNF, and long-term outcomes in patients with bipolar disorder.
Multiple cognitive impairments are common in patients with bipolar disorder. Preliminary evidence shows that aerobic exercise might have positive effects in enhancing cognition and improving clinical symptoms in patients with mood disorders. This randomized controlled trial will investigate short-term (1 months) effects of aerobic exercise on cognition and clinical symptoms as well as the long-term (12 months) effects on decreasing the recurrence rate.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
DSM diagnostic criteria
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Cycling at the intensity of 50%-70% of maximum heart rate (220-age) for 30 mins per day, 4 days per week, last for 1 month.
Behavioral: aerobic exercise
General intensity activities of recreation therapy, including Handicraft manufacture, reading activity, singing entertainment, walking.
Behavioral: Placebo controlled group
Cycling at the intensity of 50%-70% of maximum heart rate (220-age) for 30 mins per day, 4 days per week, last for 1 months.
General intensity activities of recreation therapy, including Handicraft manufacture, reading activity, singing entertainment, walking.
Changes in neurocognitive function
Changes in neurocognitive function measured by the MATRICS Consensus Cognitive Battery (MCCB) after three months (12 weeks) of aerobic exercise
Time frame: 12 months
Changes in neurocognitive function
Changes in neurocognitive function measured by the MATRICS Consensus Cognitive Battery (MCCB) after three months (12 weeks) of aerobic exercise
Time frame: Changes in neurocognitive function measured by the MATRICS Consensus Cognitive Battery (MCCB) after three months (12 weeks) of aerobic exercise
relapse rate
Relapses of depressive and/or hypo/manic episodes
Time frame: 12 months
depressive symptoms
depressive symptoms measured by Hamilton Depression Scale
Time frame: 4 weeks, 4 months, 12 months
manic symptom
manic symptom measured by Young Manic Rating Scale
Time frame: 4 weeks, 4 months, 12 months
Plan to share: Undecided
No publications or documents are linked to this record.
Start is estimated for Dec 2017; primary completion for Jul 2019, 19 months later.
Of 354 non-industry interventional studies with no phase under Bipolar Disorder, half reached primary completion within 37 months of starting (the median), counting those still running; a quarter within 23 and three quarters within 58. This study's planned 19 months is below that.
Counting every sponsor, half of 356 studies reached it within 37 months; a quarter within 23 and three quarters within 58.
How these figures are worked out, and which studies are left out of them.
This study is status unknown, as verified in Nov 2017. You cannot join it, but the record below documents what was studied.
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Guangzhou Psychiatric Hospital