ClinicalTrials.gg
Status unknownNCT03340649Updated Nov 13, 2017

The Predictive Value of Hepatocyte Growth Factor and Soluble Receptor s-Met in Sepsis

An observational study in Sepsis, sponsored by Jingyuan,Xu. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2017-11-13.

Sponsored by Jingyuan,Xu · Observational

The sponsor has not verified this record recently (last verified Nov 2017), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
90
Ages
18 Years to 80 Years
Sex
All
01

Study summary

To observe the changes of plasma hepatocyte growth factor and soluble receptor s-Met levels in patients with sepsis, and to explore its clinical significance.

Read the detailed description

90 patients who diagnosed as sepsis were included in this study. Then keep blood samples from these patients in the first day, the third day, detect the hepatocyte growth factor and soluble receptor s-Met level in plasma byenzyme-linked immuno sorbent assay. Record Severity of illness and survival status of every patient within 28 days. Objective to evaluate the correlation between the level of hepatocyte growth factor and soluble receptor s-Met in plasma and the prognosis of the patients.

02

Conditions studied

  • Sepsis

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03

In context

Sepsis

2,416 studies on the registry are indexed under Sepsis; 541 are open to participants now.

This study's planned enrollment of 90 is below the median of 150 across 1,162 observational studies indexed under Sepsis.

Browse Sepsis studies →

Lead sponsor

Jingyuan,Xu is the lead sponsor of 6 studies on the registry; 2 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

sepsis patients

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  1. Patients admitted to ICU diagnosed of sepsis(sepsis3.0 criteria)
  2. Patients signing

Exclusion criteria

Exclusion Criteria:

  1. Age is less than 18 years old or more than 80 years old
  2. Pregnant women
  3. Patients with tumor、hepatitis、liver cirrhosis、acute myocardial infarction、chronic renal tubular nephritis、interstitial pneumonia、acute pancreatitis、systemic lupus erythenatosus、ulcerative colitis、crohn's disease、HELLP syndrome
  4. is extension in patients with after liver transplantation
  5. Patients with chronic renal failure
  6. Patients after kidney transplantation
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

INR, PT and aPTT (clotting tests)

Blood tests of how long blood takes to clot. The INR is the prothrombin time (PT) put on a common scale; about 1 is usual for someone not taking a blood thinner.

Criteria often make an exception for people on a blood thinner such as warfarin, whose INR is raised on purpose.

05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
90 participants (estimated)
Patient registry
No

Interventions

  • Othertaking peripheral blood

    taking peripheral blood of no more than 3ml

06

What researchers measure

Primary outcomes

  1. mortality

    28-day mortality

    Time frame: 28-day

07

Study locations

1 of 1 sites recruiting
  • Zhongda Hospital
    Nanjing, Jiangsu 210000, China
    Recruiting
08

References and documents

Individual participant data

Plan to share: No — no share IPD

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 13, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03340649
Lead sponsor
Jingyuan,Xu
Responsible party
Jingyuan,Xu (Attending doctor, Southeast University, China) — Sponsor-investigator
First posted
Nov 13, 2017
Start date
Nov 9, 2017 (estimated)
Primary completion
Nov 9, 2017 (estimated)
Completion
Mar 1, 2018 (estimated)
Last update
Nov 13, 2017

Study contacts

chenglong liang, master
Contact
15261893562@163.com
15261893562
yi yang, doctor
Contact
yiyiyang2004@163.com
+8602583262550
yi yang, doctor
principal investigator · Zhongda Hospital

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Nov 2017. You cannot join it, but the record below documents what was studied.

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