CClinicalTrials.gg
CompletedNCT03306199Updated Apr 8, 2019Results posted

TurboPower + DCB Treatment of Femoropopliteal De Novo/ Restenotic and In-Stent Restenosis Lesions

An observational study in Peripheral Arterial Disease, sponsored by Spectranetics Corporation. Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2019-04-08.

Sponsored by Spectranetics Corporation · Observational

Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
82
Sex
All
01

Study summary

A retrospective study to evaluate Turbo Power laser atherectomy + drug coated balloon (DCB) angioplasty for the treatment of femoropopliteal de novo/restenotic lesions and in-stent restenosis (ISR).

02

Conditions studied

03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients are recruited from the investigator's general patient population, and they must meet the inclusion/exclusion criteria.

Inclusion criteria

  • All patients treated for femoropopliteal de novo/restenotic lesions or in-stent restenosis using Turbo Power laser atherectomy plus drug coated balloon angioplasty

Exclusion criteria

Exclusion Criteria:

  • Any incomplete data on procedural approach and treatment
04

Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
82 participants (actual)
Patient registry
No

Interventions

  • DeviceLaser Atherectomy

    The Turbo-Power is a laser atherectomy catheter designed for treatment of de novo or restenotic lesions in native infrainguinal arteries and for the treatment of femoropopliteal artery in-stent restenosis (ISR) in bare nitinol stents with adjunctive percutaneous transluminal angioplasty (PTA).

05

What researchers measure

Primary outcomes

  1. Number of Participants Free From Target Lesion Revascularization (TLR)

    A Target Lesion Revascularization is defined as any percutaneous or surgical intervention to treat a restenosis or reocclusion in the target lesion

    Time frame: 1 year

06

Results

Posted Apr 8, 2019

Participant flow

Participant flow — Overall Study
MilestoneTurbo Power + DCB
Started82
Completed67
Not completed15

Outcome measures

PrimaryNumber of Participants Free From Target Lesion Revascularization (TLR)

A Target Lesion Revascularization is defined as any percutaneous or surgical intervention to treat a restenosis or reocclusion in the target lesion

Time frame:
1 year
Reported as:
Count of participants · Participants
Number of Participants Free From Target Lesion Revascularization (TLR)
ParticipantsTurbo Power + DCB
Number of Participants Free From Target Lesion Revascularization (TLR)52

Adverse events

Collected over 1 year. Non-serious events are listed at a 5% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Turbo Power + DCB2/67 (3%)16/67 (23.9%)—
Most frequent serious events
Most frequent serious events
EventTurbo Power + DCB
TLRVascular disorders15/67
DeathCardiac disorders2/67
AmputationVascular disorders0/67

Baseline characteristics

Age, Continuous
Age, Continuous(years)Turbo Power + DCB
Mean70.2 ± 13.8
Sex: Female, Male
Sex: Female, Male(Participants)Turbo Power + DCB
Female42
Male40
Race and Ethnicity Not Collected
Race and Ethnicity Not Collected(Participants)Turbo Power + DCB
Region of Enrollment
Region of Enrollment(participants)Turbo Power + DCB
United States82
07

Study locations

1 site
  • Cardiovascular Institute of the South
    Houma, Louisiana 70360, United States
08

References and documents

Study documents

  • Protocol and statistical analysis plan · Mar 20, 2018

Documents are hosted by the registry — open the source record to download them.

Individual participant data

Plan to share: No

09

Registry details

Key details

Study ID
NCT03306199
Lead sponsor
Spectranetics Corporation
Responsible party
Sponsor
First posted
Oct 10, 2017
Start date
Oct 3, 2017
Primary completion
Jun 5, 2018
Completion
Jun 5, 2018
Results posted
Apr 8, 2019
Last update
Apr 8, 2019

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2019. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion