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CompletedNCT03296046LPLBUpdated Sep 28, 2017

Epidemiologic Study of Persistent Polyclonal B-cell Lymphocytosis (PPBL)

An observational study in Persistent Polyclonal B-Cell Lymphocytosis, sponsored by Central Hospital, Nancy, France. Completed at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-09-28.

Sponsored by Central Hospital, Nancy, France · Observational

Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
100
Ages
18 Years and older
Sex
All
01

Study summary

The main purpose of this study is the description of all French cases of PPBL and the establishment of minimal criteria for the pathology diagnosis and its follow-up.

The secondary objective is the immunologic and genetic characterization of lymphoid cells causing the disease.

02

Conditions studied

  • Persistent Polyclonal B-Cell Lymphocytosis
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

PPBL patients in France

Inclusion criteria

  • PPBL diagnosis established during a previous medical visit

Exclusion criteria

Exclusion Criteria:

  • None
04

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
100 participants (actual)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • PPBL patients

    Biological: Blood test

Interventions

  • BiologicalBlood test

    30 ml

05

What researchers measure

Primary outcomes

  1. Relevant medical history

    Time frame: Baseline

  2. Complete blood count

    Time frame: Baseline

  3. Administration of first-line treatment or not

    Time frame: Baseline

Secondary outcomes

  1. Lymphocyte phenotype

    Time frame: Baseline

06

Study locations

2 sites
  • group GFHC and intergroup LLC (GCFLL-MW / GOELAMS)
    Marseille, France
  • CHRU de Nancy - Hopitaux de Brabois
    Vandœuvre-lès-Nancy, France
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03296046
Lead sponsor
Central Hospital, Nancy, France
Responsible party
Sponsor
First posted
Sep 28, 2017
Start date
Nov 13, 2012
Primary completion
Dec 31, 2015
Completion
Dec 31, 2015
Last update
Sep 28, 2017

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Sep 2017. You cannot join it, but the record below documents what was studied.

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