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CompletedNCT03288753Updated Mar 23, 2023

Comparison Between Neuro 1 and Neuro 2 Cochlear Implant Speech Processors

An interventional study of Satisfaction questionnaire and Speech intelligibility in quiet in Sensorineural Hearing Loss and Cochlear Hearing Loss, sponsored by Oticon Medical. Completed at 9 sites in France. Per ClinicalTrials.gov, last updated 2023-03-23.

Sponsored by Oticon Medical · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
98
Allocation
Non-randomized
Sex
All
01

Study summary

The present study aims to evaluate patient satisfaction and audiological performance with their current cochlear implant speech processor, the Neuro 1, and to compare it with the satisfaction and performance obtained with the new speech processor, the Neuro 2.

Read the detailed description

Nowadays, cochlear implants (CI) are successfully used to rehabilitate severe to profound sensorineural hearing loss. Oticon Medical recently developed a new cochlear implant system, including a new implantable internal part (Neuro Zti) and a new speech processor (Neuro 1). This new speech processor automatically detects and adapts to the sound environment, increasing the ease of listening in all situations. A second version of this speech processor has very recently been developed, called the Neuro 2. The Neuro 1 and 2 share the same signal processing characteristics and the "sound" delivered to the patient is similar. However, the Neuro 2 offers better ergonomics (smaller size and weight, rechargeable batteries...). Some improvements available on the Neuro 2 may be particularly interesting for children.

The aim of the present study is twofold: 1. Compare the satisfaction of adult and pediatric users for the speech processor Neuro 1 with their satisfaction for the Neuro 2, and 2. Show that audiological outcomes are at least as good for the Neuro 2 than for the Neuro 1.

The participants come at the hospital for three visits. The Neuro 1 is evaluated during the first visit (V1). Evaluation of the Neuro 2 takes place during the second (V2, 15 days after V1) and the third (V3, 3 months after V2).

02

Conditions studied

  • Sensorineural Hearing Loss
  • Cochlear Hearing Loss

Keywords

  • Cochlear implant
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • informed consent
  • Native French speaker or fluent French speaker
  • Patient already fitted with one or two speech processor Neuro 1 for at least 5 months

Exclusion criteria

Exclusion Criteria:

  • vulnerable patients, at the exception of children (pregnant women, persons under guardianship)
  • No Social security affiliation
  • non-compliant patient
04

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
98 participants (actual)

Study arms

  • Experimental
    Adults and children above 14 years old

    Visit 1: Satisfaction questionnaire on Neuro 1 Speech intelligibility in quiet on Neuro 1 Speech intelligibility in noise on Neuro 1 VRB (Vocale Rapide dans le Bruit) on Neuro 1 Visit 2 (15 days after V1): Satisfaction questionnaire on Neuro 2 Speech audiometry in quiet on Neuro 2 Speech audiometry in noise on Neuro 2 VRB (Vocale Rapide dans le Bruit) on Neuro 2 Visit 3 (3 months after V2): Satisfaction questionnaire on Neuro 2 Speech audiometry in quiet on Neuro 2 Speech audiometry in noise on Neuro 2 VRB (Vocale Rapide dans le Bruit) on Neuro 2

    Other: Satisfaction questionnaire · Behavioral: Speech intelligibility in quiet · Behavioral: Speech intelligibility in noise · Behavioral: VRB (Vocale Rapide dans le Bruit)

  • Experimental
    children up to 14 years old

    Visit 1 Satisfaction questionnaire on Neuro 1 Visit 2 (15 days after V1): Satisfaction questionnaire on Neuro 2 Visit 3 (3 months after V2): Satisfaction questionnaire on Neuro 2 The questionnaires have to be filled in by the parents. The child can participate in the completion of the questionnaire if he is willing and understands the questions.

    Other: Satisfaction questionnaire

Interventions

  • OtherSatisfaction questionnaire

    Participants have to complete a satisfaction questionnaire on the Neuro 1 or 2 processor.

  • BehavioralSpeech intelligibility in quiet

    The speech material corresponds to the lists of Lafon designed for cochlear implant patients. Each lists contains 17 monosyllabic words. Speech comprehension is evaluated by the percentage of correct words and the percentage of correct phonemes. Speech signals are presented at 65 dB SPL. 2 lists of 17 words are presented. At visit 1, the participants wear the sound processor Neuro 1. At visits 2 and 3, the participants wear the Neuro 2.

  • BehavioralSpeech intelligibility in noise

    The speech material corresponds to the lists of Lafon designed for cochlear implant patients. Each lists contains 17 monosyllabic words. Speech comprehension is evaluated by the percentage of correct words and the percentage of correct phonemes. Speech signals are presented at 65 dB SPL. 2 lists of 17 words are presented. The noise corresponds to a cocktail party presented at +10 dB SNR (Speech on Noise Ratio). At visit 1, the participants wear the sound processor Neuro 1. At visits 2 and 3, the participants wear the Neuro 2.

  • BehavioralVRB (Vocale Rapide dans le Bruit)

    Speech intelligibility in noise measured with the test VRB (Vocale Rapide dans le Bruit, French version of the Quick Sin). This test measures the SNR (Signal to Noise Ratio) at which the listeners understand half of the words of a sentence correctly. The outcome measure is in dB. 3 lists are presented. Speech signals are presented at 60 dB SPL.

    Also known as: french Quick SIN

05

What researchers measure

Primary outcomes

  1. Satisfaction questionnaire

    The listener has to rate his appreciation of the Neuro 1 and Neuro 2 device and the sound quality on 7 points scale. The outcome measure corresponds to averaged score. The questionnaire has been developed by Oticon Medical to investigate satisfaction patient for their current and future speech processors. This questionnaire is not validated in the literature.

    Time frame: 15 minutes

Secondary outcomes

  1. Speech comprehension in quiet

    The speech material corresponds to the lists of Lafon designed for cochlear implant patients. Each lists contains 17 monosyllabic words. Speech comprehension is evaluated by the percentage of words and the percentage of phonemes correctly repeated. This double scoring is used to avoid floor or ceiling effects that could happen with only one of these measures.

    Time frame: 15 mins

  2. Speech comprehension in Noise

    The speech material corresponds to the lists of Lafon designed for cochlear implant patients. Each lists contains 17 monosyllabic words. Speech comprehension is evaluated by the percentage of words and the percentage of phonemes correctly repeated. This double scoring is used to avoid floor or ceiling effects that could happen with only one of these measures.

    Time frame: 15 mins

  3. French Quick Sin

    This test measures the SNR (Signal to Noise Ratio) at which the listeners understand half of the words of a sentence correctly. The outcome measure is in dB.

    Time frame: 5 mins

06

Study locations

9 sites
  • Hôpital Pellegrin
    Bordeaux, 33000, France
  • Hôpital Roger Salengro
    Lille, 59037, France
  • Hôpital Edouard Herriot
    Lyon, 69003, France
  • CHRU de Nancy Hôpital central
    Nancy, 54035, France
  • CHU de Nantes Hôtel-Dieu
    Nantes, 44093, France
  • CHU Nice - Institut Universitaire de la Face et du Cou
    Nice, 06103, France
  • Hôpitaux Pédiatriques de Nice CHU-Lenval
    Nice, 06200, France
  • Hôpital Pitié Salpêtrière - APHP
    Paris, 75013, France
  • Hôpital Necker-Enfants Malades
    Paris, 75015, France
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03288753
Lead sponsor
Oticon Medical
Responsible party
Sponsor
First posted
Sep 20, 2017
Start date
Oct 2, 2017
Primary completion
Jan 11, 2019
Completion
Jan 11, 2019
Last update
Mar 23, 2023

Study contacts

Christophe Vincent, MD, PROF
principal investigator · Hôpital Roger Salengro CHRU de Lille

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
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