A Phase 3 interventional study of Cholecalciferol and Placebo in Schizophrenia, sponsored by Universitas Padjadjaran. Status unknown. Open to male participants aged 18 Years to 45 Years. Per ClinicalTrials.gov, last updated 2020-04-02.
Sponsored by Universitas Padjadjaran · Phase 3, Interventional, and Treatment
The objective of the study is to evaluate the influence of vitamin D supplementation on Serum Brain Derived Neurotrophic Factor level and cognitive function in schizophrenia treated with atypical antipsychotic. Methods: The investigator will use randomized controlled trial design. 40 chronic schizophrenia patients with vitamin D insufficiency or deficiency treated with atypical antipsychotic, will be randomly assign (1:1 ratio) to receive either daily oral cholecalciferol 2000 IU or placebo for 8 weeks. Assessment of BDNF serum and cognitive function will be performed at baseline and after 8 weeks period.
Exclusion Criteria:
Oral placebo daily for 8 weeks
Drug: Placebo
Vitamin D Cholecalciferol 2000 IU oral daily for 8 weeks
Drug: Cholecalciferol
cholecalciferol 2000 IU oral daily for 8 weeks
Oral placebo daily for 8 weeks
Cognitive Function
cognitive function as measured with standard cognitive battery
Time frame: At the end of week 8
BDNF serum level
BDNF serum level as measured with ELISA method
Time frame: At the end of week 8
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is status unknown, as verified in Mar 2020. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Universitas Padjadjaran