An interventional study of modified radical mastectomy in Systemic Inflammatory Response Syndrome, sponsored by Kocaeli University. Status unknown. Open to female participants, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-09-18.
Sponsored by Kocaeli University · Not applicable, Interventional, and Health services research
It is aimed to evaluate pathophysiology of systemic responses to trauma via using interleukin (IL) -1 and IL-6 levels and determining timing of surgery through phases of menstrual cycle.
89 female breast cancer patient who underwent modified radical mastectomy included into study. Menstrual history and hormone levels were used to determine menstrual phase: luteal, follicular, and other. IL-1β and IL-6 levels, which are related to severeness of inflammation, were measured one day before and one day after surgery. Those are statistically analysed to show effect of timing of breast surgery on responses to trauma in postmenopausal and premenopausal women during different phases of their menstrual cycles
Exclusion Criteria:
postmenopausal female breast cancer patients who underwent modified radical mastectomy
Procedure: modified radical mastectomy
premenopausal female breast cancer patients who underwent modified radical mastectomy
Procedure: modified radical mastectomy
systemic responses to trauma are compared with evaluating inflammatory cytokine levels between premenopausal and postmenopausal patient groups with different estrogen levels who underwent modified radical mastectomy.
IL-1 and IL-6 levels
evaluate pathophysiology of systemic responses to trauma via using IL-1 and IL-6 levels.
Time frame: 5 month
No study locations are listed for this record.
This study is status unknown, as verified in Sep 2017. You cannot join it, but the record below documents what was studied.
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Systemic Inflammatory Response Syndrome→
Kocaeli University