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CompletedNCT03281850Updated Sep 25, 2026

The GLOWING Study: Growing Life, Optimizing Wellness 2

An observational study in Healthy, sponsored by Arkansas Children's Hospital Research Institute. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-25.

Sponsored by Arkansas Children's Hospital Research Institute · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
212
Ages
18 Years and older
Sex
All
01

Study summary

This study will help us learn more about how maternal health can influence child health.

Read the detailed description

This study follows people who are healthy and less than 36 weeks pregnant to see how the mother's health can impact their child's growth and development. Up to 300 people including the mother and their future child will be a part of this study. The study will follow the child until they are two years of age.

02

Conditions studied

  • Healthy
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Sampling method
Non-probability sample

Study population

A prospective longitudinal cohort of 150 dyads (pregnant women and offspring)

Inclusion criteria

  • Pre-pregnancy BMI 18.5-45
  • Singleton pregnancy
  • at least 18 years of age
  • conceived without assisted fertility treatments

Exclusion criteria

Exclusion Criteria:

  • Preexisting medical conditions (e.g. DM, GDM, CRF, HTN, pre-eclampsia or eclampsia, malignancies, seizure disorder, lupus, serious psychiatric disorders)
  • sexually transmitted diseases
  • medications during pregnancy known to influence fetal growth
  • smoking, alcohol drinking or drug use during pregnancy
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
212 participants (actual)
Target follow-up
2 Years
Patient registry
Yes
Biospecimen retention
Samples without dna
05

What researchers measure

Primary outcomes

  1. Determine energy expenditure in children

    Using stable isotope techniques to determine energy expenditure

    Time frame: 2 years

  2. Determine fat oxidation in children

    Using stable isotope techniques to determine fat oxidation

    Time frame: 2 years

06

Study locations

1 site
  • Arkansas Children's Nutrition Center
    Little Rock, Arkansas 72202, United States
07

References and documents

Publications

  • Diaz EC, Williams DK, Cotter M, Sims CR, Wolfe RR, Andres A, Borsheim E. Breastfeeding duration modifies the association between maternal weight status and offspring dietary palmitate oxidation. Am J Clin Nutr. 2022 Aug 4;116(2):404-414. doi: 10.1093/ajcn/nqac097. PubMed 35404455 ↗
08

Registry details

Key details

Study ID
NCT03281850
Lead sponsor
Arkansas Children's Hospital Research Institute
Responsible party
Sponsor
First posted
Sep 13, 2017
Start date
Sep 11, 2017
Primary completion
Nov 23, 2020
Completion
Nov 23, 2020
Last update
Sep 25, 2026

Study contacts

Aline Andres, PhD
principal investigator · Arkansas Children's Nutrition Center

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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