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CompletedNCT03261869Updated Aug 25, 2017

EFFICACY OF ICE PACK THERAPY AFTER IMPACTED THIRD MOLAR SURGERY

An interventional study of Cold application in Impacted Third Molar Tooth, sponsored by Baskent University. Completed. Open to participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-08-25.

Sponsored by Baskent University · Not applicable, Interventional, and Supportive care

From the registry’s dates

  • Registered 7 months after the study started (first participant enrolled Jan 2017, registered Aug 2017).
Phase
Not applicable
Study type
Interventional
Enrollment
18
Allocation
Randomized
Ages
18 Years to 30 Years
Sex
All
01

Study summary

this study evaluates the effect of cold application after impacted third molar extractions. Patients have bilateral impacted third molar tooth included in this study. Patients do not applied cold after extraction of third molar on one side and applied cold cold after extraction of third molar on the other side.

Read the detailed description

Extraction of impacted teeth causes a trauma which results in an inflammatory response. Some postoperative symptoms may occur such as edema, pain, limitations in mouth opening and dysfunction as a consequence of the wisdom tooth extraction surgery.

Local cold application reduces the magnitude of postoperative symptoms. The physiological effects of cold application are as follows: vasoconstriction of blood vessels, blood flow to the region decreases, edema and inflammation decreases, slowdown in cell metabolism and a decrease in local oxygen demand due to the vasoconstriction effect of the cold. Cold therapy also induces muscle constriction which reduces muscle stress, pain and inflammation.

02

Conditions studied

  • Impacted Third Molar Tooth

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Keywords

  • Ice pack therapy, third molar surgery, swelling, pain, trismus
03

In context

Pain

10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.

This study's enrollment of 18 is below the median of 66 across 8,493 interventional studies indexed under Pain.

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Lead sponsor

Baskent University is the lead sponsor of 209 studies on the registry; 35 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 30 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Bilateral bony mandibular third molar impactions
  • Has no systemic disease

Exclusion criteria

Exclusion Criteria:

  • Different Pell-Gregory classification of impacted teeth
  • Previous or current gastric ulcer
  • Allergies or to any common medications
  • pregnant or breastfeeding patients
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Hypersensitivity

An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.

05

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Single (Investigator)
Enrollment
18 participants (actual)

Study arms

  • Experimental
    Cold application

    Cold applied after extraction of third molar tooth.

    Other: Cold application

  • No intervention
    No Cold application

    Cold application is not advised after extraction of third molar tooth

Interventions

  • OtherCold application
06

What researchers measure

Primary outcomes

  1. Post operative Visual Analogue Scale Scores

    Time frame: pre-operative-postoperative 7th day

  2. Post operative facial swelling

    Time frame: pre-operative-postoperative 7th day

  3. Post-operative mouth opening

    Time frame: pre-operative-postoperative 7th day

Secondary outcomes

  1. Complications after impacted third molar removal

    Time frame: pre-operative-postoperative 7th day

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 25, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03261869
Lead sponsor
Baskent University
Responsible party
Nurettin Diker (Research Assistant at deparment of oral and maxillofacial surgery, Baskent University) — Principal investigator
First posted
Aug 25, 2017
Start date
Jan 1, 2017
Primary completion
Mar 1, 2017
Completion
Mar 1, 2017
Last update
Aug 25, 2017

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2017. You cannot join it, but the record below documents what was studied.

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