CClinicalTrials.gg
CompletedNCT03254251Updated Nov 3, 2020

The Effects of Stair Climbing on Arterial Stiffness, Blood Pressure and Leg Strength in Stage-1 Postmenopausal Women

An interventional study of Stair climbing in Hypertension and Menopause, sponsored by Pusan National University. Completed. Open to female participants aged 58 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-11-03.

Sponsored by Pusan National University · Not applicable, Interventional, and Health services research

Phase
Not applicable
Study type
Interventional
Enrollment
41
Allocation
Randomized
Ages
58 Years to 60 Years
Sex
Female
01

Study summary

We used a parallel experimental design. Following an initial screening and familiarization session of study tests and procedures, eligible postmenopausal women were randomly assigned to a stair climbing (SC) group or non-exercising control group. SC training session was progressive program, and was performed 4 days a week for 12 weeks. Measurements were collected at baseline and after 12 weeks during the same time of day (±1 hour) in the morning following an overnight fast and abstinence from caffeinated drinks, alcohol, and between 48 and 72 hours after the last exercise session.

02

Conditions studied

  • Hypertension
  • Menopause
03

Who can participate

Ages eligible
58 Years to 60 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Inclusion criteria

  • Stage-1 hypertension
  • Postmenopausal

Exclusion criteria

Exclusion Criteria:

  • Pulmonary, renal, adrenal, pituitary, severe psychiatric, thyroid, or cardiovascular disease other than stage-1 systolic hypertension (140-159 mmHg)
  • Hormone replacement therapy during the 6 months prior the study
  • Smoker or having any medication changes in the previous year
  • Experience with psychological and physical therapy in the previous year
  • History of steady exercise or exercise training in the last year
04

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
41 participants (actual)

Study arms

  • Experimental
    Stair Climbing (SC)

    N=20, 12 weeks of stair climbing exercise training.

    Behavioral: Stair climbing

  • No intervention
    No Exercise (CON)

    N=21, No exercise for 12 weeks

Interventions

  • BehavioralStair climbing

    Stair climbing (SC) training was 12 weeks of progressive SC program. Each training session consisted of a general warm-up (5 min: slow and fast skipping, stretching) followed by the SC training and was supervised by experienced personnel. The program began with two bouts of stair climbing four days a week in weeks 1 and 2, increasing by one climb a day every three weeks. By the last three weeks (10-12) of the study, all subjects were completing 5 climbs four days a week. During each climb participants ascended 12 flights (192 steps) divided into 3 sets of 4 flights, with a 2 min rest period between each set. There was a 5 min rest period between climbs that allowed the participants to reach the ground floor using an elevator. Subjects in the non-exercising control group did not participate in a supervised exercise program for the duration of the study.

05

What researchers measure

Primary outcomes

  1. Arterial stiffness

    Arterial stiff ness was measured by brachial to ankle pulse wave velocity (baPWV, m/s) using volume plethysmographic device (VP-1000).

    Time frame: 12 weeks

  2. Blood pressure (BP)

    BP (mmHg) was measured by volume plethysmographic device. Diastolic blood pressure and systolic blood pressure were measured.

    Time frame: 12 weeks

  3. Muscle strength

    Muscle strength was measured by the eight repetition maximum (8RM) test using extension machine (Cyber 6000).

    Time frame: 12 weeks

  4. Body composition

    Body composition was measured using eight-polar tactile-electrode impedance meter (InBody 720). Body weight (kg), fat mass (kg), and fat free mass (kg) were assessed.

    Time frame: 12 weeks

  5. Height

    Height (m) was measured with a stadiometer

    Time frame: 12 weeks

  6. Heart rate (HR)

    Heart rate was measured by ECG

    Time frame: 12 weeks

  7. Body mass index (BMI)

    BMI was calculated as weight/height\^2 (kg/m\^2)

    Time frame: 12 weeks

06

Study locations

No study locations are listed for this record.

07

References and documents

Publications

  • Wong A, Figueroa A, Son WM, Chernykh O, Park SY. The effects of stair climbing on arterial stiffness, blood pressure, and leg strength in postmenopausal women with stage 2 hypertension. Menopause. 2018 Jul;25(7):731-737. doi: 10.1097/GME.0000000000001072. Erratum In: Menopause. 2021 Feb 1;28(2):230. doi: 10.1097/GME.0000000000001717. PubMed 29438269 ↗
08

Registry details

Key details

Study ID
NCT03254251
Lead sponsor
Pusan National University
Collaborators
Dong-Eui University, University of Nebraska
Responsible party
Won-mok son (postdoctoral fellow, Pusan National University) — Principal investigator
First posted
Aug 18, 2017
Start date
Jan 9, 2017
Primary completion
Apr 3, 2017
Completion
Apr 10, 2017
Last update
Nov 3, 2020

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2020. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion