An observational study in Trauma, Spinal Cord and SPINAL Fracture, sponsored by Ohio State University. Active, not recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-08-11.
Sponsored by Ohio State University · Observational
Among 13 studies in Spinal Cord Injuries by Ohio State University — 3 open to participants now, 4 under way, none of them phase 3. Spinal Cord Injuries · Ohio State University.
Among the 13 studies in Spinal Cord Injuries by Ohio State University, this one is one of 2 that started in 2017, is one of 3 observational ones, and was the 5th registered.
2,025 studies on the registry are indexed under Spinal Cord Injuries; 537 are open to participants now.
This study's planned enrollment of 50 is below the median of 60 across 332 observational studies indexed under Spinal Cord Injuries.
Browse Spinal Cord Injuries studies →3 of the 13 studies in Spinal Cord Injuries by Ohio State University are open now, in 2 countries. Each count lists the studies.
Of the 375 Spinal Cord Injuries studies recruiting now, 166 (44%) set no upper age limit and 158 (42%) stop at 75 or younger; 41 take children under 18; 52 take healthy volunteers.
This study: 18 Years and older · all sexes · no healthy volunteers.
The full table on the hub →13 studies; the count open now beside each. This study's row is marked.
First in 2013; this study’s year is marked. 2 started in 2017.
Median enrollment 21 across the 10 interventional studies, 50 across the 3 observational. Of the 9 that completed or were terminated, 2 (22%) have results posted.
Ohio State University is the lead sponsor of 663 studies on the registry; 148 are open to participants now.
Of its 67 completed or terminated interventional studies of FDA-regulated products, 49 (73%) have results posted.
2 of the studies in Spinal Cord Injuries by Ohio State University that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT06882460Ohio State UniversityDiet and Exercise Solutions to Postprandial Hypotension | 2026-12-01 |
| NCT05337982Ohio State UniversityEccentric Muscle Training, Stimulation, and Biomarkers in SCI | 2026-12-31 |
Among the 13 studies in Spinal Cord Injuries by Ohio State University, from their registry updates:
The study is designed to investigate whether autonomic shifts (dysautonomia, sympatho-vagal instability) that develop after SCI have value in predicting SCI-associated infections (SCI-AI). SCI-AI impair outcomes by (1) reducing the intrinsic neurological recovery potential and (2) increasing mortality. Heart Rate Variability (HRV) data will be tracked in both the time and frequency domains to discriminate between the relative contribution of sympathetic and parasympathetic innervation to changes in HRV. The ability to predict infections will enable novel treatments thereby reducing infection-associated mortality and improving neurological and functional outcomes.
SCI patients (n=50 subjects), Isolated Spinal fracture patients (n=10)
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Observational study - monitoring immune response and heart rate variability
Observational study - monitoring immune response and heart rate variability acting as a control group.
Sympatho-vagal instability as an identifier for patients at risk for Spinal Cord Injury Associated Infections
Determining whether discrete signs of loss of autonomic control (dysautonomia), not meeting defined criteria of full-autonomic dysreflexia, also renders patients "at risk" for developing infections.
Time frame: At all study time-points for a period of 24hours.
Ran from Sep 2017 to primary completion in Jun 2025, 93 months.
Of 124 non-industry observational studies under Spinal Cord Injuries, half reached primary completion within 36 months of starting (the median), counting those still running; a quarter within 16 and three quarters within 74. This study's 93 months is above that.
Counting every sponsor, half of 135 studies reached it within 39 months; a quarter within 16 and three quarters within 78.
How these figures are worked out, and which studies are left out of them.
This study is active, not recruiting, as verified in Aug 2025. You cannot join it, but the record below documents what was studied.
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