An interventional study of Adductor Canal perineural catheter placement and Femoral Nerve perineural catheter placement in Pain, Postoperative and Anterior Cruciate Ligament Injury, sponsored by Stanford University. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-07-24.
Sponsored by Stanford University · Not applicable, Interventional, and Treatment
Nerve blocks are used to provide pain control after moderately painful orthopedic surgeries. Anterior Cruciate Ligament (ACL) reconstruction with patellar autograft is a painful orthopedic procedure performed after traumatic injury to the knee. Many patients undergoing ACL reconstruction receive a nerve block as part of their anesthetic care. These blocks can be performed in different locations along the femoral nerve, with advantages and disadvantages to each location. Recently published evidence indicates that there is no short-term difference in pain control between the two commonly-targeted locations ("Adductor Canal" and "Femoral"). However, studies involving patients undergoing total knee arthroplasty indicate that femoral blocks provide better pain control with movement than adductor canal blocks. As many patients undergoing ACL reconstruction use continuous passive motion (CPM) machines as part of rehabilitation starting on post-operative day one, the investigators hypothesize that pain control and quality of recovery in the first 48 hours after surgery will be superior with a continuous femoral block than with a continuous adductor canal block. The investigators plan to study this by randomizing patients presenting for ACL reconstruction to receive either a continuous femoral or continuous adductor canal block (both considered adequate means of pain control), and following them to 48 hours to determine the level of pain, quality of recovery score, opioid use, and CPM compliance.
covery score, opioid use, and CPM compliance.
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Exclusion Criteria:
Adductor Canal perineural catheter placement. Adductor Canal continuous perineural infusion. Ropivacaine 0.2% will be administered at a continuous rate of 5 mL/hour through a perineural catheter placed in the adductor canal. A Nimbus pump (Infutronix) will be delivering the medication.
Procedure: Adductor Canal perineural catheter placement · Device: Nimbus pump (Infutronix)
Femoral Nerve perineural catheter placement. Femoral continuous perineural infusion. Ropivacaine 0.2% will be administered at a continuous rate of 5 mL/hour through a perineural catheter placed near the femoral nerve. A Nimbus pump (Infutronix) will be delivering the medication.
Procedure: Femoral Nerve perineural catheter placement · Device: Nimbus pump (Infutronix)
Patients will receive an Adductor Canal Block intervention for pain control following ACL reconstructive surgeries.
Also known as: Adductor Canal block
Patients will have a Femoral perineural catheter placed for pain control following ACL reconstructive surgery.
Also known as: Femoral Nerve Block
This is a FDA approved infusion device that is used in standard of care to store pain medication and to provide patients with continuous pain control medication at a set rate. This pump will be used for both the Adductor Canal and Femoral Nerve block participants.
Pain Score
Participants will report pain on a numeric rating scale
Time frame: Post-operative day 2
Quality of Recovery
The Quality of Recovery 15 (QoR 15) is a 15-item questionnaire that is often used to assess how patients are doing in their post-operative course. This survey will be used to assess participants' quality of recovery after ACL reconstructive surgery.
Time frame: POD 2
Opioid Use
Total morphine equivalents used through POD 2
Time frame: POD 2
CPM compliance
number of hours of reported CPM usage through POD 2
Time frame: POD 2
Quality of Recovery
The Quality of Recovery 15 (QoR 15) is a 15-item questionnaire that is often used to assess how patients are doing in their post-operative course. This survey will be used to assess participants' quality of recovery after ACL reconstructive surgery.
Time frame: POD 1
Bolus dose usage
Total volume of patient-administered bolus doses over the course of the infusion
Time frame: POD 2
Return to Play
Binary variable, whether patient has returned to normal sports activities
Time frame: 3 months
Quadriceps Circumference, percent of baseline
Quadriceps Circumference in cm measured 3 months after surgery, divided by pre-surgery circumference
Time frame: 3 months
Plan to share: No
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This study is completed, as verified in Jul 2023. You cannot join it, but the record below documents what was studied.
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