CClinicalTrials.gg
Status unknownNCT03188614Updated Jun 15, 2017

Crystalloids for AKI in Shock Patients

An interventional study of Fluid resuscitation in Shock, sponsored by Southeast University, China. Status unknown. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-06-15.

Sponsored by Southeast University, China · Not applicable, Interventional, and Prevention

The sponsor has not verified this record recently (last verified Jun 2017), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
40
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Fluid resuscitation is important in shock therapy, but the choice of fluids, especially the choice of crystalloid is under debate. It is said that normal saline is related to hyperchloremia, which might lead to acute kidney injury. Thus the hypothesis of the study is to explicit whether balanced salt solution could reduce the incidence of acute kidney injury when compared with normal saline.

02

Conditions studied

  • Shock

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Keywords

  • shock
  • crystalloid
  • acute kidney injury
03

In context

Shock

916 studies on the registry are indexed under Shock; 176 are open to participants now.

This study's planned enrollment of 40 is below the median of 77 across 540 interventional studies indexed under Shock.

Browse Shock studies →

Lead sponsor

Southeast University, China is the lead sponsor of 164 studies on the registry; 44 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Shock patients

Exclusion criteria

Exclusion Criteria:

  • History of chronic renal failure
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Single group
Masking
None (open label)
Enrollment
40 participants (estimated)

Study arms

  • Placebo comparator
    Normal saline group

    Shock patients who resuscitated with normal saline were enrolled between June, 2015-June.2016.

    Drug: Fluid resuscitation

  • Experimental
    Balanced solution group

    Shock patients who resuscitated with balanced solution were enrolled after June, 2016.

    Drug: Fluid resuscitation

Interventions

  • DrugFluid resuscitation

    The placebo group is resuscitated with normal saline, the experimental group is resuscitated with balanced fluid.

06

What researchers measure

Primary outcomes

  1. Incidence of acute kidney injury

    Diagnosis of acute kidney injury

    Time frame: 28-day

Secondary outcomes

  1. Usage of renal replacement of therapy

    Usage of CRRT

    Time frame: 28-day

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 15, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03188614
Lead sponsor
Southeast University, China
Responsible party
Jingyuan,Xu (Principal Investigator, Southeast University, China) — Principal investigator
First posted
Jun 15, 2017
Start date
Aug 1, 2017 (estimated)
Primary completion
Sep 1, 2018 (estimated)
Completion
Oct 1, 2018 (estimated)
Last update
Jun 15, 2017

Study contacts

Jingyuan Xu, Docotor
Contact
xujingyuanmail@163.com
13851417209
Haibo Qiu, Doctor
principal investigator · Southeast University

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jun 2017. You cannot join it, but the record below documents what was studied.

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