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CompletedNCT03176446Updated Apr 30, 2020

Pain and Anxiety Evaluation in Children Using Different Techniques of Local Anesthesia for Dental Treatment

An interventional study of Local anesthesia with traditional technique and Local anesthesia with computerized technique in Pediatric Dentistry, Local Anesthesia and Pain Management, sponsored by Universidade Estadual de Ponta Grossa. Completed at 1 site in Brazil. Open to participants aged 5 Years to 12 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-04-30.

Sponsored by Universidade Estadual de Ponta Grossa · Not applicable, Interventional, and Device feasibility

Phase
Not applicable
Study type
Interventional
Enrollment
210
Allocation
Randomized
Ages
5 Years to 12 Years
Sex
All
01

Study summary

Fear and dental anxiety are often associated with the use of needles and syringes for local anesthesia, and painful perception during the administration of local anesthetics is often the main reason for anxiety behaviors and defensive reactions. Dental trauma originates in childhood, through experience misconduct. The objective of this study is to evaluate the pain and anxiety related to 4 different modalities of anesthesia in children. Will be selected volunteers aged between 5 and 12 years who need restorative dental treatment in posterior teeth in the upper 2 quadrants. All patients will receive 1 modality of anesthesia: conventional anesthesia (control group), computerized anesthesia, Dental Vibe anesthesia and computerized anesthesia + DentalVibe anesthesia. Evaluations will be made with physiological and behavioral criteria. For the physiological evaluation will be measured the blood pressure, respiratory rate, heart rate, oximetry and salivary cortisol before and during each anesthesia. As criteria for evaluation of anxiety will be applied the methods, Corah and modified VPT before anesthesia and modified VPT will be repeated after anesthesia. The pain will be assessed at the end of each anesthesia with Visual Analogue Scale (VAS) and Wong Baker Faces. The results will be submitted to parametric and non-parametric statistical analysis, according to the data obtained in the different evaluation criteria.

02

Conditions studied

  • Pediatric Dentistry
  • Local Anesthesia
  • Pain Management
03

Who can participate

Ages eligible
5 Years to 12 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Children of both sexes, aged between 5 and 12 years, requiring dental treatment under local anesthesia in the first permanent molars or deciduous maxilla.

Exclusion criteria

Exclusion Criteria:

  • The person responsible does not authorize the participation of the child as a research volunteer.
  • Be using pain modulating drugs.
  • Be using anxiety modulating drugs.
  • Patients with a history of hypersensitivity to local anesthetics.
  • Patients with a history of systemic diseases.
04

Study design

Phase
Not applicable
Primary purpose
Device feasibility
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
210 participants (actual)

Study arms

  • Active comparator
    Control Group

    The children anesthesia will be traditional technique

    Device: Local anesthesia with traditional technique · Drug: Topic anesthesia · Drug: Local anesthetic

  • Active comparator
    Computerized Group

    The children anesthesia will be computerized technique

    Device: Local anesthesia with computerized technique · Drug: Topic anesthesia · Drug: Local anesthetic

  • Active comparator
    DentalVibe Group

    The children anesthesia will be DentalVibe technique

    Device: Local anesthesia with DentalVibe technique · Drug: Topic anesthesia · Drug: Local anesthetic

Interventions

  • DeviceLocal anesthesia with traditional technique

    Puncture with short needle in the region of the apical third of the tooth to be anesthetized Injection of local anesthetic, with speed 1ml / min

    Also known as: Traditional anesthesia, Conventional anesthesia

  • DeviceLocal anesthesia with computerized technique

    Puncture with short needle in the region of the apical third of the tooth to be anesthetized according to the recommendations of the manufacturer Injection of local anesthetic with computerized anesthesia equipment, with speed 0.5 ml / min

    Also known as: Computerized anesthesia

  • DeviceLocal anesthesia with DentalVibe technique

    Use of DentalVibe in the apical region of the tooth to be anesthetized according to the manufacturer's guidelines Puncture with short needle enters the tips of the DentalVibe Injection of local anesthetic with traditional carpule, with speed 1 ml / min

    Also known as: DentalVibe anesthesia

  • DrugTopic anesthesia

    Application of topical anesthetic for 60 seconds with benzocaine

    Also known as: Topical anesthesia

  • DrugLocal anesthetic

    2% lidocaine with epinephrine 1: 100000 1.8 mL

    Also known as: Anesthetic

05

What researchers measure

Primary outcomes

  1. Self-perception of pain

    The pain will be analyzed by the Wong Baker Faces scales

    Time frame: Immediately after anesthesia

  2. Pain Behavior

    The pain will be analyzed by the FLACC

    Time frame: During the anesthetic procedure

  3. Self-perception of pain

    The pain will be analyzed by the Visual Analogue Scale (0-10). 0- no pain, 10- severe pain

    Time frame: Immediately after anesthesia

Secondary outcomes

  1. SCARED Questionnaire

    Children will be evaluated for the anxiety behavior prior to any anesthesia by answering the SCARED questionnaire

    Time frame: Before anesthesia

  2. Corah Questionnaire

    Children will be evaluated for the dentistry anxiety prior to any anesthesia

    Time frame: Before anethesia

  3. VPT modified

    Children will be evaluated for the anxiety after to any anesthesia

    Time frame: Before anethesia and immediately after anesthesia

  4. Blood pressure

    The physiological response of anxiety to local dental anesthesia will be evaluated by parameters of blood pressure

    Time frame: Immediately before anesthesia, during anesthesia

  5. Respiratory rate

    The physiological response of anxiety to local dental anesthesia will be evaluated by parameters of respiratory rate

    Time frame: Immediately before anesthesia, during anesthesia

  6. Heart rate

    The physiological response of anxiety to local dental anesthesia will be evaluated by parameters of heart rate

    Time frame: Immediately before anesthesia, during anesthesia

  7. Oxygen saturation

    The physiological response of anxiety to local dental anesthesia will be evaluated by parameters of oxygen saturation

    Time frame: Immediately before anesthesia, during anesthesia

  8. Salivary cortisol

    The physiological response of anxiety to local dental anesthesia will be evaluated by parameters of salivary cortisol

    Time frame: Immediately before anesthesia, during anesthesia

06

Study locations

1 site
  • Ponta Grossa State University
    Ponta Grossa, Paraná 84030900, Brazil
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03176446
Lead sponsor
Universidade Estadual de Ponta Grossa
Responsible party
Priscila de Camargo Smolarek (PhD student, Universidade Estadual de Ponta Grossa) — Principal investigator
First posted
Jun 5, 2017
Start date
Oct 1, 2017
Primary completion
Nov 30, 2018
Completion
Mar 1, 2019
Last update
Apr 30, 2020

Oversight

FDA-regulated drug
No
FDA-regulated device
No
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