An interventional study of Exposure therapy in Complex Regional Pain Syndromes, sponsored by Uppsala University. Completed at 1 site in Sweden. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2017-06-02.
Sponsored by Uppsala University · Not applicable, Interventional, and Treatment
Consecutive patients with long-standing complex regional pain syndrome II in a lower limb are treated with graded exposure therapy in vivo in combination with methods targeting cortical reorganisation.
Complex regional pain syndrome, CRPS, is an uncommon but often very handicapping chronic pain syndrome. Most often, a single extremity is affected. The diagnosis is subdivided in CRPS type I where no nerve injury has been identified, and CRPS type II when a major nerve injury has been verified. With the exception of spontaneous pain, several of the symptoms related to CRPS may be connected to the inactivity and immobilization often seen in the history of CRPS patients.
Exposure in vivo, a form of behaviour therapy where the patient is gradually confronted with the avoided movements and activities, has been shown safe and effective for patients with CRPS type I. The present study uses a combination of exposure in vivo and interventions targeting a supposed cortical reorganisation with the hypothesis that the functional impairments would decrease, independent of possible changes in pain levels.
Consecutive patients with long-standing CRPS-II, diagnosed according to the Budapest criteria, in a lower limb are included. Treatment comprises daily graded exposure therapy in vivo, in combination with methods targeting cortical reorganisation: mirror therapy, desensibilisation training, and sensory re-education. The treatment is implemented at an in-patient ward during four plus four weeks, separated by a home training period of 6-8 weeks.
198 studies on the registry are indexed under Complex Regional Pain Syndromes; 55 are open to participants now.
This study's enrollment of 4 is below the median of 40 across 146 interventional studies indexed under Complex Regional Pain Syndromes.
Browse Complex Regional Pain Syndromes studies →Uppsala University is the lead sponsor of 381 studies on the registry; 84 are open to participants now.
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Graded exposure therapy in vivo in combination with methods targeting cortical reorganisation.
Behavioral: Exposure therapy
Daily training at an in-patient ward during four plus four weeks, separated by a home training period of 6-8 weeks.
Also known as: Mirror therapy, Desensibilisation training, Sensory re-education
Photograph series of daily activities, PHODA
A measure of avoidance of activities - the subject reports level of hesitation in performing a number of everyday activities on a 0-100 rating scale.
Time frame: 12 weeks
The Tampa Scale of Kinesiophobia - Short Form, TSK-SF
Fear of movement, assessed with a questionnaire
Time frame: 12 weeks
Plan to share: No
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This study is completed, as verified in May 2017. You cannot join it, but the record below documents what was studied.
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Complex Regional Pain Syndromes→
Uppsala University