An interventional study of inspiratory muscle training and Placebo "training" in Chronic Thromboembolic Pulmonary Hypertension, Inspiratory Muscle Training and Inspiratory Muscle Weakness, sponsored by Federal University of São Paulo. Completed at 1 site in Brazil. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2025-09-18.
Sponsored by Federal University of São Paulo · Not applicable, Interventional, and Treatment
Inspiratory muscle training for 8 weeks in patients with pulmonary hypertension.
32 patients with PH will perform: 1) pulmonary function tests; 2) measurement of maximal inspiratory pressure (MIP) and endurance; 3) six-minute walk test and 5) incremental and constant load cardiopulmonary exercise test (\~ 75% of maximal work-rate) and step test. Inspiratory muscle training will consist of twice daily sessions of 30 breaths (\~ 50% PiMAX, 4-5 minutes per session) for 8 weeks. The SHAM group will perform sessions of 30 breaths with no inspiratory load.
761 studies on the registry are indexed under Pulmonary Arterial Hypertension; 142 are open to participants now.
This study's enrollment of 32 is below the median of 38 across 509 interventional studies indexed under Pulmonary Arterial Hypertension.
Browse Pulmonary Arterial Hypertension studies →Federal University of São Paulo is the lead sponsor of 427 studies on the registry; 22 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
inspiratory muscle training (PowerBREATHE) with \~50% of maximum inspiratory pressure
Other: inspiratory muscle training
inspiratory muscle training (PowerBREATHE) without inspiratory load
Other: Placebo "training"
inspiratory muscle training with 50% of MIP
placebo training with PowerBreathe (without inspiratory load)
exercise capacity¨- cardiopulmonary exercise testing
TLim (seconds)
Time frame: week 8
exercise capacity - 6-min walk test
distance (m)
Time frame: week 8
ventilatory responses
VE/VCO2
Time frame: Week 8
Plan to share: Yes
No publications or documents are linked to this record.
This study is completed, as verified in Sep 2025. You cannot join it, but the record below documents what was studied.
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Pulmonary Arterial Hypertension→
Federal University of São Paulo