CClinicalTrials.gg
CompletedNCT03102151ReduceDUPUpdated Jan 11, 2023

Reducing the Duration of Untreated Psychosis

An observational study in First Episode Psychosis, sponsored by University of Southern California. Completed at 1 site in United States. Open to participants aged 15 Years to 65 Years. Per ClinicalTrials.gov, last updated 2023-01-11.

Sponsored by University of Southern California · Observational

Study type
Observational
Model
Ecologic or community
Time perspective
Prospective
Enrollment
137
Ages
15 Years to 65 Years
Sex
All
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Study summary

The study examines the possible effect of a community campaign to decrease the duration of untreated psychosis in persons with their first episode of a psychotic disorder.

Read the detailed description

The study examines whether a community campaign can reduce over time the duration of untreated psychosis (DUP) among persons with first episode psychosis (FEP). The DUP of mental health patients with FEP who sought services at a public outpatient or an inpatient facility was assessed for a 15 month period prior to the campaign launch. This serves as the baseline or historical control. The DUP will continue to be assessed for another 3 years. The hypothesis being tested is that there will be a significant decrease in DUP between baseline, one-year, two-year and three-year follow-ups. This study is being carried out with Latinos in Los Angeles County because as a group, particularly among Spanish-speaking immigrants, Latinos are at high risk for prolonged DUP.

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Conditions studied

  • First Episode Psychosis
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In context

Psychotic Disorders

1,626 studies on the registry are indexed under Psychotic Disorders; 293 are open to participants now.

This study's enrollment of 137 is close to the median of 150 across 245 observational studies indexed under Psychotic Disorders.

Browse Psychotic Disorders studies →

Lead sponsor

University of Southern California is the lead sponsor of 773 studies on the registry; 135 are open to participants now.

Of its 68 completed or terminated interventional studies of FDA-regulated products, 32 (47%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
15 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Living in the catchment area of San Fernando Mental Health Outpatient clinic, a clinic with the Los Angeles County Department of Mental Health

Inclusion criteria

  • Meet Diagnostic and Statistical Manual-4 criteria for a psychotic disorder
  • of Latino origin

Exclusion criteria

Exclusion Criteria:

  • has a neurological disorder or suffers from brain trauma
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Study design

Observational model
Ecologic or community
Time perspective
Prospective
Enrollment
137 participants (actual)
Patient registry
No

Interventions

  • OtherCommunity Campaign La CLAVE

    A community campaign to teach community residents and professional networks the signs and symptoms of psychosis using social media, community talks, and advertising.

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What researchers measure

Primary outcomes

  1. Latency to Treatment (LTT) a novel interview based assessment tool to measure the Duration of Untreated Psychosis

    The time from the onset of psychosis to the time the subject receives appropriate mental health treatment. The metric is number of weeks that the person went without treatment from illness onset. The number of weeks is the variable of interest that will be aggregated.

    Time frame: At the time of recruitment into the study

Secondary outcomes

  1. Psychosis literacy, a questionnaire based inquiry for which the respondents answer either open-ended questions (e.g., What is serious mental Illness?) or "Yes-no" questions ("e.g., Can you recognize a serious mental illness in others?)

    The responses to the interview are either written down or audio-recorded. Raters then listen or read the responses and code them. The responses are aggregated as frequencies (e.g., the number of symptoms identified) or as percentages (e.g., the proportion of respondents who reported that they can recognize a serious mental illness in others).

    Time frame: At the time of recruitment in to study

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Study locations

1 site
  • San Fernando Mental Health Center
    Granada Hills, California 91344, United States
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 11, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03102151
Lead sponsor
University of Southern California
Collaborators
University of California, Los Angeles, National Institute of Mental Health (NIMH)
Responsible party
Steven R. Lopez (Professor, University of Southern California) — Principal investigator
First posted
Apr 5, 2017
Start date
May 2014
Primary completion
Dec 31, 2018
Completion
Aug 30, 2019
Last update
Jan 11, 2023

Study contacts

Steven Lopez, PhD
principal investigator · University of Southern California

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2023. You cannot join it, but the record below documents what was studied.

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