An observational study in Cardiac Remodeling, Ventricular, sponsored by University Hospital, Caen. Completed at 1 site in France. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2024-02-13.
Sponsored by University Hospital, Caen · Observational
The uncertainty concerning the onset and the extent of cardiac remodeling in response to intensive training hinders medical evaluation by physician. A better knowledge of the physiology of cardiac adaptation to training will enable physicians to correctly determine whether observed patterns of cardiac remodeling are physiological or pathological. This prospective study proposes to assess in a trained-athlete population the cardiac remodeling in response to intensive exercise training. This study is observational, we do not interfere with athlete's training.
105 studies on the registry are indexed under Ventricular Remodeling; 24 are open to participants now.
This study's enrollment of 100 is below the median of 180 across 32 observational studies indexed under Ventricular Remodeling.
Browse Ventricular Remodeling studies →University Hospital, Caen is the lead sponsor of 512 studies on the registry; 82 are open to participants now.
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Athletes
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Exclusion Criteria:
Professional and amateur athletes examined during the medical follow-up at the medical sport centre of Caen University Hospital. The medical examination consists in a clinical exam, an electrocardiogram and an echocardiography.
Other: electrocardiogram and echocardiography
Sedentary patients assessed in the cardiology unit with a normal heart function. The medical examination consists in a clinical exam, an electrocardiogram and an echocardiography.
Other: electrocardiogram and echocardiography
We retrieved all electrocardiograms and echocardiography made during the clinical examination of each athlete and each sedentary control. * Standard 12 lead ECG * Trans-thoracic echocardiography examination of cardiac function, morphology and intracardiac flow.
Evaluation of ventricular response to exercise training by echocardiography.
1. 2D- morphological and functional parameters of both left and right ventricles: * end-diastolic and end-systolic dimensions (cm) * left ventricular mass (g) * ventricular end-diastolic and end-systolic areas (cm²) * ventricular ejection fraction (%) * atrial volumes (ml) * diastolic indices by pulsed wave Doppler and tissue Doppler (cm/s) * myocardial deformation by speckle tracking (%) 2. 3D- morphological and functional parameters of both left and right ventricles: * ventricular full volumes (ml) * ejection fraction (%) 3. Intracardiac flow measurements by color Doppler M-mode: estimation of intra ventricular pressure gradients between the base and the apex (mmHg).
Time frame: Day 1
Evaluation of ventricular response to exercise training by electrocardiogram
* heart rate (bpm), * ventricular hypertrophy (mV) * atrial remodeling (mV)
Time frame: Day 1
Sport and medical history questionnaire
exercise training program, medical past history, cardiovascular risk factors, treatments, doping.
Time frame: Day 1
Plan to share: No
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This study is completed, as verified in Feb 2024. You cannot join it, but the record below documents what was studied.
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