An observational study in Allergy, Asthma and Urticaria, sponsored by University of Nebraska. Terminated at 1 site in United States. Open to participants aged 19 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-08-28.
Sponsored by University of Nebraska · Observational
This study evaluates blood type 2 innate lymphoid cells in participants with mild to moderate asthma and participants with chronic urticaria as compared to healthy adult participants.
The first objective of this study is to determine whether blood ILC2s differ in female vs. male allergic asthmatics. This is because females become more susceptible to asthma after puberty and experience more severe disease as adults.
The second objective of this study is to determine whether ILC2 cells in chronic urticaria differ from healthy controls.
There will be one shared healthy control adult subject group for comparison for objective 1 and 2.
In this study, there will be a blood draw once on 3 different adult populations aged 19-50 years: 1) Participants with mild-to moderate allergic asthma; 2) Participants with chronic urticaria, and 3) Healthy control adult participants. Demographics and allergy indicators will be collected from the medical chart. The investigators will acquire whole blood for serum and acquisition of specific lymphocyte populations. There will be no intervention or research follow up.
237 studies on the registry are indexed under Urticaria; 26 are open to participants now.
This study's enrollment of 18 is below the median of 162 across 52 observational studies indexed under Urticaria.
Browse Urticaria studies →University of Nebraska is the lead sponsor of 473 studies on the registry; 66 are open to participants now.
Of its 75 completed or terminated interventional studies of FDA-regulated products, 46 (61%) have results posted.
Counted across the registry records on this site, refreshed daily.
Adult subjects age 19-50 years.
Exclusion Criteria:
Healthy adult subjects between the ages of 19-50 years will be enrolled.
Adult subjects between the ages of 19-50 years with mild-to-moderate asthma seen within the UNMC Allergy and Pulmonary Clinics will be invited to be enrolled.
Adult subjects between the ages of 19-50 years with chronic urticaria seen within the UNMC Allergy Clinics will be invited to be enrolled.
ILC2 Phenotype
Blood ILC2s responsiveness will be determined solely for research purposes using ex vivo stimulation assays.
Time frame: 52 weeks
Plan to share: No — Subject information will be de-identified. IPD will not be made available to other researchers.
No publications or documents are linked to this record.
This study is terminated, as verified in Aug 2023. You cannot join it, but the record below documents what was studied.
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University of Nebraska