CClinicalTrials.gg
Status unknownNCT03015987Updated Jan 11, 2017

Effect of Diode Laser Activated Irrigation Versus Ultrasonic on Post-Operative Pain in Single Visit of Necrotic Teeth

An interventional study of diode laser activated irrigation in Necrosis, sponsored by Cairo University. Status unknown. Open to participants aged 20 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-01-11.

Sponsored by Cairo University · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Jan 2017), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
44
Allocation
Randomized
Ages
20 Years to 45 Years
Sex
All
01

Study summary

the investigator intended to study the effect of laser versus ultrasonic in activation of irrigation in post operative pain of patients have a symptomatic necrotic teeth

Read the detailed description

the investigator will choose from patients entering clinic of endodontics in faculty of oral and dental medicine Cairo university who are eligible to the criteria.

After the patients is found eligible,the patients will be randomly assigned to either the control (ultrasonic activated irrigation )or to the intervention ( diode laser activated irrigation) treatment done in both in single visit.

At the end of treatment, patients will be asked to record post operative pain by NRS .

02

Conditions studied

  • Necrosis

Keywords

  • Diode laser
  • asymptomatic pulp
  • Laser activated irrigation
  • continuous ultrasonic activation
  • post obturation pain
03

In context

Pain, Postoperative

5,093 studies on the registry are indexed under Pain, Postoperative; 1,140 are open to participants now.

This study's planned enrollment of 44 is below the median of 75 across 4,344 interventional studies indexed under Pain, Postoperative.

Browse Pain, Postoperative studies →

Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 45 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Asymptomatic necrotic single rooted single canal teeth with or without chronic periradicular lesion.
  • Teeth with mature root
  • Teeth without calcified root canals
  • Teeth without root caries
  • Teeth without internal or external root resorption
  • Teeth with no sign of crack formation
  • Teeth without anatomic abnormalities

Exclusion criteria

Exclusion Criteria:

  • Pregnant or lactating females
  • Teeth with vital pulp
  • Non- restorable teeth
  • Medically compromised patients
  • Patients with facial swelling or acute infection.
  • Previously endodontically treated teeth
  • periodontally affected teeth
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
44 participants (estimated)

Study arms

  • Experimental
    diode laser activated irrigation

    Laser-activated irrigation (LAI) has been introduced as a powerful method enhancing irrigant action; The laser radiation produces transient cavitation in the liquid through optical breakdown by strong absorption of the laser energy. The high-power diode laser has been tested in several areas of dentistry such as bleaching, depigmentation and gingivectomy, with promising results in dentinal disinfection. The diode laser has proved to be a resource worth testing, because of the it's properties and its low cost and availability in comparison to most lasers used in endodontics.

    Other: diode laser activated irrigation

  • Active comparator
    ultrasonic activated irrigation

    ultrasonics have been developed to improve the penetration and effectiveness of irrigation in peripheral areas of the root canal space. The efficiency of sonic and ultrasonic devices is based on the creation of hydrodynamic phenomenon in well-shaped canals filled with an irrigant. Such active root canal irrigation has been shown to facilitate the disruption of biofilms and make the cell membrane of bacteria more permeable to NaOCl.

    Other: diode laser activated irrigation

Interventions

  • Otherdiode laser activated irrigation

    diode laser became the most common and affordable type of laser used in endodontics for many uses , its disinfection effect is an important issue which not discussed in clinical trial before , So this study is assigned to study that

    Also known as: diode laser

06

What researchers measure

Primary outcomes

  1. post operative pain

    intensity of post operative pain will be measured using a numerical rating (NRS)scale

    Time frame: up to 1 week

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • 1-Sathorn C, Parashos P, Messer H. The prevalence of postoperative pain and flare-up in single- and multiple-visit endodontic treatment: a systematic review. Int Endod J 2008; 41:91-9. 2-.Ng YL, Glennon JP, Setchell DJ. Prevalence of and factors affecting post. obturation pain in patients undergoing root canal treatment. Int Endod J 2004;37:381-91. 3-Peters OA. Current challenges and concepts in the preparation of root canal systems a review. J Endod 2004; 30:559-67. 4- Gu L, Kim JR, Ling J. Review of contemporary irrigant agitation techniques and devices. J Endod 2009; 35:791-804.

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 11, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03015987
Lead sponsor
Cairo University
Responsible party
zeinab mostafa omar (principal investigator, Cairo University) — Principal investigator
First posted
Jan 10, 2017
Start date
Feb 2017
Primary completion
Jan 2018 (estimated)
Completion
Feb 2018 (estimated)
Last update
Jan 11, 2017

Study contacts

Zeinab M Omar, student
Contact
dentistonline89@yahoo.com
01017111154
Ghada A Eid, Professor
Contact
ghada.eid@dentistry.cu.edu.eg
01001266608
Ghada A Eid, Professor
study chair · Department of endodontics -Faculty of Oral and Dental Medicine-Cairo university
Hanaa M El shinawy, Researcher professor
study director · Surgery &oral medicine department -National Research Institute-Cairo University
Zeinab M Omar, Student
principal investigator · Department of endodontics -Faculty of Oral and Dental Medicine-Cairo university

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2017. You cannot join it, but the record below documents what was studied.

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