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CompletedNCT03007355PPIUpdated Dec 19, 2018

Peripheral Perfusion Index (PPI) as Monitor During Deliberate Hypotensive Anesthesia

An observational study in Monitoring During Deliberate Hypotensive Anesthesia, sponsored by Cairo University. Completed. Open to participants aged 18 Years to 50 Years. Per ClinicalTrials.gov, last updated 2018-12-19.

Sponsored by Cairo University · Observational

Study type
Observational
Model
Other
Time perspective
Prospective
Enrollment
50
Ages
18 Years to 50 Years
Sex
All
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Study summary

Hypotensive anesthesia is effective in reducing the intraoperative blood loss. The risk of hypoperfusion of vital organs continues to be a concern. An adequate monitoring of tissue perfusion and oxygenation is crucial issue. Peripheral Perfusion Index (PPI) as a noninvasive new monitoring, can reflect the peripheral perfusion dynamics.

This study is designed to explore the behaviour and trend of PPI during nitroglycerine induced deliberate hypotensive anesthesia in adult patients undergoing functional endoscopic sinus surgery (FESS).

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Conditions studied

  • Monitoring During Deliberate Hypotensive Anesthesia

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In context

Hypotension

1,003 studies on the registry are indexed under Hypotension; 173 are open to participants now.

This study's enrollment of 50 is below the median of 84 across 294 observational studies indexed under Hypotension.

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Lead sponsor

Cairo University is the lead sponsor of 4,780 studies on the registry; 1,427 are open to participants now.

Of its 36 completed or terminated interventional studies of FDA-regulated products, 5 (14%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

adult male or females, aged between 18-50 years, ASA class I ans II

Inclusion criteria

  • Patients, aged from 18-50 years, ASA physical status I and II, undergoing functional endoscopic sinus surgery (FESS) under deliberate hypotensive anesthesia

Exclusion criteria

Exclusion Criteria:

  • Patients with systemic hypertension, cardiovascular disease, cerebrovascular insufficiency, coagulation defects, renal or hepatic insufficiency, and hypersensitivity to the study drugs will be excluded from the study. Patients receiving vasoactive drugs or beta blockers will be also excluded from the study.
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Study design

Observational model
Other
Time perspective
Prospective
Enrollment
50 participants (actual)
Patient registry
No

Interventions

  • Otherperipheral perfusion index measurement
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What researchers measure

Primary outcomes

  1. correlation between PPI and T1

    correlation of baseline values of PPI and time required to achieve target mean arterial pressure.

    Time frame: start of nitroglyceirn infusion till target arterial pressure is reached up to 2 hours

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Study locations

No study locations are listed for this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 19, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03007355
Lead sponsor
Cairo University
Responsible party
Abeer Ahmed, MD (Lecturer of Anesthesia - Faculty of Medicine, Cairo University) — Principal investigator
First posted
Jan 2, 2017
Start date
Jan 2017
Primary completion
Oct 2017
Completion
Dec 2017
Last update
Dec 19, 2018

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2018. You cannot join it, but the record below documents what was studied.

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