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CompletedNCT02999490Updated Apr 20, 2018

18F-FDG PET/CT in Diagnostic Patients of Disorder of Consciousness

An interventional study of 18F-FDG in Persistent Vegetative State, sponsored by Guangzhou General Hospital of Guangzhou Military Command. Completed at 1 site in China. Open to participants aged 10 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-04-20.

Sponsored by Guangzhou General Hospital of Guangzhou Military Command · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Non-randomized
Ages
10 Years to 75 Years
Sex
All
01

Study summary

Clinical examinations are difficult to discriminate between vegetative state and minimally conscious state. the diagnostic and prognostic usefulness of neuroimaging methods has not been established in a clinical setting. we will do a forward study of PET imaging in disorders of consciousness patients, and validate with clinical assessments with the coma recovery Scale-Revised(CRS-R).

Read the detailed description

Every patient need to be conducted the PET/CT scanning two times.The first time is resting state.The second time is stimulated state by watching a vedio.

02

Conditions studied

  • Persistent Vegetative State
03

In context

Persistent Vegetative State

88 studies on the registry are indexed under Persistent Vegetative State; 20 are open to participants now.

This study's enrollment of 20 is below the median of 30 across 55 interventional studies indexed under Persistent Vegetative State.

Browse Persistent Vegetative State studies →

Lead sponsor

Guangzhou General Hospital of Guangzhou Military Command is the lead sponsor of 46 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
10 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Clinical diagnosis of disorder of consciousness

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • No intervention
    Controls

    The controls are intravenous injected of 185 to 370 MBq 18F-FDG.Then,the controls sleep for an hour in a quiet room before scanning.

  • Experimental
    Patients

    The patients are intravenous injected of 185 to 370 MBq 18F-FDG.Then,the patients sleep for an hour in a quiet room before scanning.

    Radiation: 18F-FDG

Interventions

  • Radiation18F-FDG

    18F-FDG is positron emission tomography imaging agent which is already widely used in PET/CT examination.

06

What researchers measure

Primary outcomes

  1. standardized uptake value

    Time frame: 60 mins after injecting 18F-FDG

07

Study locations

1 site
  • The PET/CT Centre Guangzhou General Hospital of Guangzhou Military Command
    Guangzhou, Guangdong 510000, China
08

References and documents

Individual participant data

Plan to share: Yes

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Mar 2016, a primary completion of Dec 2017 and a completion of Dec 2017. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Mar 25, 2016
First posted
Dec 21, 2016
Start
Mar 2016
Primary completionActual
Dec 1, 2017
CompletionActual
Dec 5, 2017
Last update
Apr 20, 2018
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 20, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02999490
Lead sponsor
Guangzhou General Hospital of Guangzhou Military Command
Responsible party
Jing Zhao (Clinical Professor, Guangzhou General Hospital of Guangzhou Military Command) — Principal investigator
First posted
Dec 21, 2016
Start date
Mar 2016
Primary completion
Dec 1, 2017
Completion
Dec 5, 2017
Last update
Apr 20, 2018

Study contacts

Yin Jilin
study director

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2018. You cannot join it, but the record below documents what was studied.

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