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CompletedNCT02960321TRIP-CZUpdated Jan 6, 2017

Troponin Release Induced by Procedure - Czech

An observational study in Coronary Artery Disease, sponsored by Tomas Bata Hospital, Czech Republic. Completed. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-01-06.

Sponsored by Tomas Bata Hospital, Czech Republic · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
220
Ages
18 Years and older
Sex
All
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Study summary

A prospective study aiming to analyse the relation between different variables and high sensitivity troponin I (hsTnI) elevation within a group of patients undergoing a coronary angiography with or without subsequent percutaneous coronary intervention.

Read the detailed description

The study tries to seek potential causes and context of subclinical myocardial injury within patients with baseline concentration of hsTnI below the 99th percentile value upper reference limit or with demonstrated fall of hsTnI levels.

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Conditions studied

  • Coronary Artery Disease

Keywords

  • myocardial injury
  • high-sensitivity troponin I
  • periprocedural myocardial infarction
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In context

Coronary Artery Disease

5,598 studies on the registry are indexed under Coronary Artery Disease; 957 are open to participants now.

This study's enrollment of 220 is below the median of 336 across 1,947 observational studies indexed under Coronary Artery Disease.

Browse Coronary Artery Disease studies →

Lead sponsor

Tomas Bata Hospital, Czech Republic is the lead sponsor of 11 studies on the registry; 4 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Consecutive patients referred for coronary angiography (CAG): stable patients with presumed coronary artery disease, or those referred for acute coronary syndrome without ST-segment elevation (NSTE-ACS) meeting the criteria of low risk with demostrated fall of cTn levels, or patients prepared for cardiac surgery.

Inclusion criteria

  • stable or unknown coronary artery disease
  • acute coronary syndrome without ST-segment elevation meeting the criteria of low risk with demonstrated fall of cTn levels

Exclusion criteria

Exclusion Criteria:

  • acute coronary syndrome with persistent ST-segment elevation
  • acute coronary syndrome without ST-segment elevation meeting the criteria of high or intermediate risk
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
220 participants (actual)
Patient registry
No

Groups and cohorts

  • CAG without PCI

    Diagnostic coronary angiography only

  • CAG with PCI

    Diagnostic coronary angiography and subsequent percutaneous coronary intervention (PCI)

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What researchers measure

Primary outcomes

  1. Subclinical myocardial injury

    Time frame: up to 24 hours after procedure

Secondary outcomes

  1. Postprocedural myocardial infarction

    Time frame: up to 24 hours after procedure

07

Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Griva M, Stastny J, Kopriva P, Slabak M, Coufal Z, Jarkovsky J, Svoboda M, Salek T, Sukupova L, Taborsky M. Selective coronary angiography, percutaneous coronary intervention and asymptomatic peri-procedural myocardial injury. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2019 Dec;163(4):324-330. doi: 10.5507/bp.2018.066. Epub 2018 Nov 6. PubMed 30398220 ↗

Individual participant data

Plan to share: No

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 6, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02960321
Lead sponsor
Tomas Bata Hospital, Czech Republic
Responsible party
Sponsor
First posted
Nov 9, 2016
Start date
Jun 2016
Primary completion
Jun 2016
Completion
Jun 2016
Last update
Jan 6, 2017

Study contacts

Martin Griva, MD
principal investigator · Cardiac Center for Adults, Tomas Bata Hospital, Zlin, Czech Republic

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jan 2017. You cannot join it, but the record below documents what was studied.

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