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CompletedNCT02934867CONTACUpdated Jan 16, 2025

Out of Hospital Cardiac Arrest: Trial Assessing the Survival Impact of Phone Advice

An interventional study of Protocol phone advice and Usual phone advice in Out of Hospital Cardiac Arrest, sponsored by Centre Hospitalier Universitaire de Besancon. Completed at 19 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-01-16.

Sponsored by Centre Hospitalier Universitaire de Besancon · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
729
Allocation
Randomized
Ages
18 Years and older
Sex
All
01

Study summary

Medical call center have no phone advice protocol within out of hospital cardiac arrest in France. The purpose of the present study is to compare a group of patients with protocol phone advice delivered by the dispatchers ("CONTARM" group) versus usual phone advice ( "CONTHAB" group). Comparison will be performed on survival to seven days. The hypothesis is that CONTARM group has an higher survival at seven days. A second goal is to measure the survival to 15 and 30 days. The trial is randomized, controlled and will include 2600 patients. The patients will be enrolled in 19 hospitals in France.

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Conditions studied

  • Out of Hospital Cardiac Arrest
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In context

Heart Arrest

966 studies on the registry are indexed under Heart Arrest; 227 are open to participants now.

This study's enrollment of 729 is above the median of 100 across 557 interventional studies indexed under Heart Arrest.

Browse Heart Arrest studies →

Lead sponsor

Centre Hospitalier Universitaire de Besancon is the lead sponsor of 439 studies on the registry; 97 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • > 18 years old
  • initial call to 15
  • out of hospital cardiac arrest
  • patient proximity to witness

Exclusion criteria

Exclusion Criteria:

  • first aid professionals on site
  • rigor mortis
  • location not allowing resuscitation
  • inability to realize actions or misunderstanding
  • no flow > 5 minutes
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Participant, Outcomes assessor)
Enrollment
729 participants (actual)

Study arms

  • Experimental
    CONTARM

    Protocol phone advice

    Other: Protocol phone advice

  • Other
    CONTHAB

    Usual phone advice

    Other: Usual phone advice

Interventions

  • OtherProtocol phone advice

    Protocol phone advice

  • OtherUsual phone advice

    Usual phone advice

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What researchers measure

Primary outcomes

  1. 7 days survival

    7 days survival

    Time frame: 7 days

Secondary outcomes

  1. 15 and 30 days survival

    15 and 30 days survival

    Time frame: 15 and 30 days

  2. Assessment of compliance of phone advice

    Listening of phone bands to measure compliance of phone advice protocol : * good frequency of chest compression. Binary variable (Yes or Not) * good depth of chest compression. Binary variable (Yes or Not) * good patient positioning. Binary variable (Yes or No).

    Time frame: 7 days

  3. 30 days neurological status

    Cerebral performance categories scale is counting with medical file

    Time frame: 30 days

07

Study locations

19 sites
  • CHU Angers
    Angers, France
  • CHU Besançon
    Besançon, France
  • CHU Bordeaux
    Bordeaux, France
  • CH Châlon sur Saône
    Châlon sur Saône, France
  • CH Colmar
    Colmar, France
  • CHU Dijon
    Dijon, France
  • CH Lons Le Saunier
    Lons Le Saunier, France
  • CHU Lyon
    Lyon, France
  • CHU Metz
    Metz, France
  • CH Montauban
    Montauban, France
  • CH Mulhouse
    Mulhouse, France
  • CHU Nancy
    Nancy, France
  • CHU Nantes
    Nantes, France
  • CHU Nîmes
    Nîmes, France
  • CH Orléans
    Orléans, France
  • CHU Poitiers
    Poitiers, France
  • CHU Reims
    Reims, France
  • CHU Strasbourg
    Strasbourg, France
  • CH Troyes
    Troyes, France
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References and documents

Publications

  • Berg RA, Hemphill R, Abella BS, Aufderheide TP, Cave DM, Hazinski MF, Lerner EB, Rea TD, Sayre MR, Swor RA. Part 5: adult basic life support: 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Circulation. 2010 Nov 2;122(18 Suppl 3):S685-705. doi: 10.1161/CIRCULATIONAHA.110.970939. PubMed 20956221 ↗
  • Nolan JP, Soar J, Zideman DA, Biarent D, Bossaert LL, Deakin C, Koster RW, Wyllie J, Bottiger B; ERC Guidelines Writing Group. European Resuscitation Council Guidelines for Resuscitation 2010 Section 1. Executive summary. Resuscitation. 2010 Oct;81(10):1219-76. doi: 10.1016/j.resuscitation.2010.08.021. No abstract available. PubMed 20956052 ↗
  • Koster RW, Baubin MA, Bossaert LL, Caballero A, Cassan P, Castren M, Granja C, Handley AJ, Monsieurs KG, Perkins GD, Raffay V, Sandroni C. European Resuscitation Council Guidelines for Resuscitation 2010 Section 2. Adult basic life support and use of automated external defibrillators. Resuscitation. 2010 Oct;81(10):1277-92. doi: 10.1016/j.resuscitation.2010.08.009. No abstract available. PubMed 20956051 ↗
  • Desmettre T, Jenvrin J, Freysz M, Nace L, Puyraveau M, Berthier F, Dreyfus P, Philippe MH, Labourey JM, Capellier G. Drug prescription at the medical call center. Ann. Fr. Med. Urgence (2013) 3:14-19.
  • Sigaux A, Jonquet S, Puyraveau M, Bretillot L, Labourey JM, Capellier G, Desmettre T. Evaluation of phone advice delivered by a medical call center in case of cardiac arrest. Ann. Fr. Med. Urgence (2014) 4:11-17.
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 16, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02934867
Lead sponsor
Centre Hospitalier Universitaire de Besancon
Collaborators
Centre Hospitalier Universitaire Dijon, Central Hospital, Nancy, France, University Hospital, Metz, University Hospital, Strasbourg, France, Reims University hospital, Centre Hospitalier de Lons Le Saunier, Groupe Hospitalier de la Region de Mulhouse et Sud Alsace, Centre Hospitalier de Colmar, Centre Hospitalier de Troyes, Centre Hospitalier de Chalon sur Saône, Centre Hospitalier Universitaire de Nīmes, Nantes University Hospital, University Hospital, Bordeaux, Hospices Civils de Lyon, Poitiers University Hospital, University Hospital, Angers, University Hospital, Orléans, Centre Hospitalier de Montauban
Responsible party
Sponsor
First posted
Oct 17, 2016
Start date
Oct 12, 2016
Primary completion
Oct 12, 2021
Completion
Oct 19, 2021
Last update
Jan 16, 2025

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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