CClinicalTrials.gg
Status unknownNCT02908204Updated Sep 21, 2016

Long-term Outcomes of Superficial Esophageal Squamous Cell Carcinoma

An observational study in Esophageal Neoplasms, sponsored by Shanghai Zhongshan Hospital. Status unknown at 1 site in China. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2016-09-21.

Sponsored by Shanghai Zhongshan Hospital · Observational

The sponsor has not verified this record recently (last verified Sep 2016), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Retrospective
Enrollment
1,800
Ages
18 Years to 75 Years
Sex
All
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Study summary

Tumor is the primary public health problem and the incidence of esophageal cancer showed the increasing trend in the past thirty years. According to the statistics in 2015, the new onset of esophageal cancer is about 477,900 yearly. The mainly pathologic type of esophageal cancer in China is esophageal squamous cell carcinomas, which accounts for more than 90% of patients in China. With the development of endoscopic technics, more and more patients choose to receive the endoscopic procedure rather than traditional surgery. However, the long-term efficacy and outcomes of patients with superficial esophageal squamous cell carcinoma received different interventions remained unclear. Thus, investigators aim to conduct a multi-center retrospective study to investigate the long term outcomes of superficial esophageal squamous cell carcinoma patients receiving endoscopic treatment and surgery.

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Conditions studied

  • Esophageal Neoplasms

Keywords

  • superficial esophageal squamous cell carcinoma
  • efficacy
  • survival
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In context

Carcinoma

6,741 studies on the registry are indexed under Carcinoma; 1,161 are open to participants now.

This study's planned enrollment of 1,800 is above the median of 149 across 1,175 observational studies indexed under Carcinoma.

Browse Carcinoma studies →

Lead sponsor

Shanghai Zhongshan Hospital is the lead sponsor of 636 studies on the registry; 283 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with superficial esophageal squamous cell carcinoma underwent endoscopic treatment or traditional surgery.

Inclusion criteria

  • Patients received endoscopic treatment because of the superficial esophageal disease and had the pathologic diagnosis of squamous cell carcinoma.

Exclusion criteria

Exclusion Criteria:

  • Combined with other severe disease
  • With a history of esophageal surgery
  • Combined with other malignant disease
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Study design

Observational model
Cohort
Time perspective
Retrospective
Enrollment
1,800 participants (estimated)
Patient registry
No

Groups and cohorts

  • Endoscopic treatment

    Patients underwent endoscopic treatment including Endoscopic Mucosal Resection (EMR), Endoscopic Submucosal Dissection (ESD), Multiband Mucosectomy (MBM), Endoscopic Mucosal Band Ligation(EMBL) and so on.

  • Traditional surgery

    Patients underwent traditional surgery

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What researchers measure

Primary outcomes

  1. Overall survival

    Time frame: 3 years after treatment

Secondary outcomes

  1. Recurrence rate

    Time frame: 3 years after treatment

  2. Short-term complications incidence rate

    Time frame: 30 days after treatment

  3. Long-term complications incidence rate

    Time frame: 3 years after treatment

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Study locations

1 of 1 sites recruiting
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 21, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02908204
Lead sponsor
Shanghai Zhongshan Hospital
Collaborators
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Tongji Hospital, The affiliated Hospital of Shihezi University
Responsible party
Shiyao Chen (Professor, Shanghai Zhongshan Hospital) — Principal investigator
First posted
Sep 20, 2016
Start date
Oct 2016
Primary completion
Oct 2017 (estimated)
Last update
Sep 21, 2016

Study contacts

Shiyao CHEN, PhD
Contact
chen.shiyao@zs-hospital.sh.cn
13601767310

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2016. You cannot join it, but the record below documents what was studied.

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