An observational study in Focal Epilepsy, sponsored by Fondation Ophtalmologique Adolphe de Rothschild. Completed at 1 site in France. Open to participants aged 18 Months to 17 Years. Per ClinicalTrials.gov, last updated 2018-09-18.
Sponsored by Fondation Ophtalmologique Adolphe de Rothschild · Observational
Reconstruction software allows visualization of cortical structure in 3 dimensions, showing on a single picture the position of all the electrodes. The EEG signal of each recording plot of the electrode is analyzed and compared with the underlying brain structure reconstructed by the software. It is therefore possible to visualize 1) ictogenic and epileptogenic areas using neurophysiological stereoelectroencephalography (SEEG) data and 2) adjacent functional cortical areas with functional imaging and SEEG. Software makes it possible to determine the links between these areas. This study aims to show that using these software is an asset in surgical decision and in the choice of surgical strategy.
Each patient has presurgical evaluation (usual care), including morphologic and (if necessary) functional MRI, EEG and SEEG. In this study, software will be used to analyze the processed data (FSL software, FMRIB laboratory, Oxford University and BrainVisa/Anatomist. The surgical decision will be taken according to the usual staff procedures, based on the usual examination results. After the decision making process, the staff will be asked to reconsider the surgical decision, according to the analysis provided by the software. The discrepancies between the decisions will be recorded.
1,805 studies on the registry are indexed under Epilepsy; 417 are open to participants now.
This study's enrollment of 30 is below the median of 102 across 521 observational studies indexed under Epilepsy.
Browse Epilepsy studies →Fondation Ophtalmologique Adolphe de Rothschild is the lead sponsor of 311 studies on the registry; 77 are open to participants now.
Counted across the registry records on this site, refreshed daily.
patients with drug resistant focal epilepsy, potential candidates for surgery, scheduled for deep brain electrodes exploration.
Exclusion Criteria:
number of patients for whom surgical strategy would change if using the software
change in medical strategy includes surgery indication, resection volume, topography of resection area
Time frame: 1 day
This study is completed, as verified in Jan 2018. You cannot join it, but the record below documents what was studied.
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Fondation Ophtalmologique Adolphe de Rothschild