An interventional study of narrow band imaging withdrawal and white light withdrawal in Colon Cancer and Colon Sessile Serrated Adenoma/Polyp, sponsored by Hospital Beatriz Ângelo. Status unknown at 3 sites in Portugal. Open to participants aged 40 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-09-26.
Sponsored by Hospital Beatriz Ângelo · Not applicable, Interventional, and Treatment
Colorectal cancer (CRC) is a leading cause of cancer death and its' incidence is rising in most European countries. Colonoscopy has been shown to reduce CRC incidence, however its effectiveness depends on the sensitivity to detect pre-malignant lesions.
Our aim is to evaluate narrow band imaging (NBI) during colonoscopy and serum miRNAs as novel tools for the early detection of colonic sessile serrated lesions (SSL). The investigators will perform a multicenter-randomized-controlled-trial to study the role of NBI in SSL detection.
657 studies on the registry are indexed under Adenoma; 98 are open to participants now.
This study's planned enrollment of 987 is above the median of 250 across 412 interventional studies indexed under Adenoma.
Browse Adenoma studies →Hospital Beatriz Ângelo is the lead sponsor of 8 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
colonoscope withdrawal and mucosal inspection performed under narrow band imaging
Device: narrow band imaging withdrawal
colonoscope withdrawal and mucosal inspection performed under white light imaging
Device: white light withdrawal
colonoscope withdrawal and mucosal inspection performed under narrow band imaging
colonoscope withdrawal and mucosal inspection performed under white light imaging
average number of serrated lesions ≥10 mm detected per colonoscopy
Time frame: immediate
Serrated class lesions detection rate
number of patients with at least 1 lesion/total number of participants
Time frame: immediate
Serrated lesions <10 mm detected per colonoscopy
Time frame: immediate
SSL detection rate
histologically defined according to the WHO criteria
Time frame: immediate
Adenoma detection rate
number of patients with at least 1 adenoma/total number of participants
Time frame: immediate
Adenomas detected per colonoscopy
Time frame: immediate
Advanced (malignant) adenocarcinoma detection rate
Time frame: immediate
Incidence of procedure related adverse events
Time frame: immediate
Plan to share: No
This study is status unknown, as verified in Sep 2018. You cannot join it, but the record below documents what was studied.
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Hospital Beatriz Ângelo