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Active, not recruitingNCT02875535RLASUpdated Jun 4, 2025

Implementing Evidence Informed Practices in Schools to Address LGBTQ Adolescent Suicide

An interventional study of RLAS in Suicide, sponsored by Pacific Institute for Research and Evaluation. Active, not recruiting. Open to participants aged 16 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2025-06-04.

Primary conditionSuicide(the registry's first term)UnverifiedIs this wrong?Suicide is a broad heading, used only when no more specific condition is named. No better condition is named, so the registry's term is kept.

Sponsored by Pacific Institute for Research and Evaluation · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
43
Allocation
Randomized
Ages
16 Years and older
Sex
All
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Study summary

Reducing youth suicide in the U.S. is a national public health priority. Sexual and gender minority adolescents are at elevated risk for suicide. Safer school environments, however, can decrease this risk. This study capitalizes on the critical role of school nurses in improving the mental health of this vulnerable population through implementation and sustainment of evidence-based strategies to enhance school environments. In addition to suicide, the conceptual framework and methods for this novel, nurse-led intervention can be applied to address the health-related concerns of other pediatric populations encountered in school settings as well.

Read the detailed description

Reducing youth suicide in the U.S. is a national public health priority. A supportive and safe school environment is pivotal to preventing youth suicide, and schools are now widely accepted as part of the de facto mental healthcare infrastructure for adolescents. Lesbian, gay, bisexual, transgender, and queer (LGBTQ) youth are at elevated risk for suicide. Safer school environments decrease this risk. The school nurse is well positioned to implement evidence-based (EB) strategies to enhance school environments and improve the mental health of all students, particularly members of this vulnerable population. These strategies include the creation of "safe spaces," adoption of harassment and bullying prohibitions, improved access to community health and mental health providers experienced in working with youth and LGBTQ people, school staff development, and incorporation of LGBTQ-specific information into health education curricula. These strategies promote positive mental health outcomes for LGBTQ youth, and their cisgender, heterosexual peers as well.

The investigators of this nursing intervention model is called "RLAS" (Implementing School Nursing Strategies to Reduce LGBTQ Adolescent Suicide). The model builds on the Exploration, Preparation, Implementation, and Sustainment conceptual framework and the Dynamic Adaptation Process (DAP), a structured methodology for implementing the EB strategies. The DAP accounts for the multi-level context of school settings, facilitates appropriate expertise and feedback to make them "implementation ready," and provides for targeted training of school nurses. Per the DAP, the nurses and other school professionals will convene and lead Implementation Resource Teams (IRTs) consisting of counselors, social workers, health educators, and youth. With the guidance of coaches, the IRTs will engage in an iterative process of assessment and planning to build school capacity and implement the EB strategies. To evaluate this model, the investigators will combine qualitative methods with population-based surveys and pursue three specific aims.

First, the investigators will utilize the DAP to enable specially-trained nurse champions and IRTs to implement and sustain EB strategies to address the needs of LGBTQ high school students. Second, the investigators will conduct a cluster randomized controlled trial (RCT) to assess whether sexual minority students and their peers in RLAS schools report reductions in suicidality, depression, substance use, and bullying, and increased safety compared to those in usual care schools. Third, the investigators will examine the individual, school, and community factors influencing both implementation and outcomes. The RLAS keeps with national priorities to: (a) improve school-based services for pediatric populations; (b) focus on LGBTQ youth mental health; and (c) revolutionize the role of nurses in U.S. healthcare. Through its collaborative processes to refine, improve, and sustain EB strategies in these systems, the RLAS also represents a novel and innovative contribution to implementation science.

02

Conditions studied

  • Suicide

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Keywords

  • Evidence-based
  • lesbian, gay, bisexual, transgender, intersex, and queer
  • adolescent
  • Suicide prevention
  • Implementation study
03

In context

Suicide Unverified

607 studies on the registry are indexed under Suicide; 162 are open to participants now.

This study's enrollment of 43 is below the median of 104 across 490 interventional studies indexed under Suicide.

Browse Suicide studies →

Lead sponsor

Pacific Institute for Research and Evaluation is the lead sponsor of 15 studies on the registry; 1 is open to participants now.

Compared within Suicide, the registry's first condition term, which may not be this study's main condition. Counted across the registry records on this site, refreshed daily. How we classify →

04

Who can participate

Ages eligible
16 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Located within New Mexico;
  • Designated public high school;
  • School nurse that is willing and available to support the RLAS intervention and to lead and convene an IRT; and
  • School administrator that is willing and available to support the RLAS intervention.

Exclusion criteria

Exclusion criteria for schools:

  • Unable to participate in the NM-YRRS.
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
43 participants (actual)

Study arms

  • No intervention
    Usual Care

    Standard school nurse care for suicide prevention.

  • Experimental
    Dynamic Adaption Process

    Investigators will train school nurses statewide. Using the Dynamic Adaptation Process, the nurses will then convene and lead Implementation Resource Teams (IRTs). With the assistance of RLAS coaches, the school nurse-led IRTs will engage in an iterative process of assessment and planning to build school capacity and implement up to six evidence-base strategies to reduce adolescent suicide.

    Behavioral: RLAS

Interventions

  • BehavioralRLAS

    The implementation model for this intervention will increase school-based supports and safety for gender and sexual minorities and broader student bodies, and be applicable to addressing other priority child and adolescent health and mental health issues within schools. The investigators refer to the model as "RLAS" (Implementing School Nursing Strategies to Reduce LGBTQ Adolescent Suicide).

    Also known as: Dynamic Adaptation Process

06

What researchers measure

Primary outcomes

  1. Adherence to EB strategy implementation

    Demonstration of adherence to the Centers for Disease Control and Prevention recommended EB strategies to enhance school environments

    Time frame: 5 years

Secondary outcomes

  1. Reduced suicidality and depression measured by the New Mexico Youth Risk and Resiliency Study (NM-YRRS)

    Self-reported suicidality and depression for youth as measured by the NM-YRRS

    Time frame: 5 years

  2. Substance use measured by the NM-YRRS

    Self-reported substance use for youth as measured by the NM-YRRS

    Time frame: 5 years

  3. Feelings of safety measured by the NM-YRRS

    Self-Reported experiences of bullying and safety concerns for youth as measured by the NM-YRRS

    Time frame: 5 years

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Willging CE, Green AE, Ramos MM. Implementing school nursing strategies to reduce LGBTQ adolescent suicide: a randomized cluster trial study protocol. Implement Sci. 2016 Oct 22;11(1):145. doi: 10.1186/s13012-016-0507-2. PubMed 27770819 ↗

Individual participant data

Plan to share: No

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 4, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02875535
Lead sponsor
Pacific Institute for Research and Evaluation
Responsible party
Cathleen Willging (Center Director, Pacific Institute for Research and Evaluation) — Principal investigator
First posted
Aug 23, 2016
Start date
May 2016
Primary completion
Dec 31, 2021
Completion
Apr 30, 2026 (estimated)
Last update
Jun 4, 2025

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is active, not recruiting, as verified in May 2025. You cannot join it, but the record below documents what was studied.

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