An interventional study of motor imagery in Tetraplegia C5-C6 and Tetraplegia C6-C7, sponsored by Hospices Civils de Lyon. Completed at 1 site in France. Open to participants aged 18 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-05-28.
Sponsored by Hospices Civils de Lyon · Not applicable, Interventional, and Supportive care
Single center, pilot study, to evaluate the influence of Motor Imagery (MI) on functional rehabilitation and cerebral plasticity through the qualitative and quantitative mental practice approach. For this, the investigators will use magnetoencephalography (MEG) but also physiological and behavioral indicators developed by the Laboratoire de la Performance Motrice, Mentale et du Matériel (P3M) of Université Claude Bernard Lyon 1 and its partners.
189 studies on the registry are indexed under Quadriplegia; 72 are open to participants now.
This study's enrollment of 16 is above the median of 13 across 162 interventional studies indexed under Quadriplegia.
Browse Quadriplegia studies →Hospices Civils de Lyon is the lead sponsor of 1,826 studies on the registry; 439 are open to participants now.
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Exclusion Criteria:
C6-C7 patients able to recover tenodesis grasp.
Procedure: motor imagery
C5-C6 patients for whom surgery for rehabilitation of an upper limb is indicated with a upper limit of one year after trauma, and after complete clinical and functional evaluation
Procedure: motor imagery
a control group (n=6) matched on age and sex to C6-C7 without medical history or neurological disorder
Intervention consisted of supervised MI during which the participants were trained to imagine performing a single-joint wrist extension movement and a multiple-joint reach-to-grasp movement using tenodesis. The two movements were practiced in separate blocks and each 45 minute MI session consisted of six to eight blocks. Within a given block patients; i) performed the movement once, ii) imagined it using visual imagery (between five and ten repetitions), iii) performed the movement again, and iv) imagined it using kinesthetic imagery (between five and ten repetitions). All movements (performed and imagined) were timed by the experimenter to ensure that the durations of both imagined and physically practiced movements were similar. Imagery vividness was controlled with self-rated assessments using a visual analogic scale (from 0, the image or feeling was absent, to 10 when it was as clear or intense as physical practice).
Motor imagery ability
Motor imagery ability assessed by magnetoencephalography measurements
Time frame: 10 weeks
Movement time (MT)
Kinematic parameters of movement: temporal parameters: movement time (MT)
Time frame: 10 weeks
absolute time to peak velocity
Kinematic parameters of movement: temporal parameters: absolute time to peak velocity
Time frame: 10 weeks
movement amplitude at peak velocity
Kinematic parameters of movement: temporal parameters: movement amplitude at peak velocity
Time frame: 10 weeks
time to opening
Kinematic parameters of movement: temporal parameters: time to opening
Time frame: 10 weeks
time to maximal opening
Kinematic parameters of movement: temporal parameters: time to maximal opening
Time frame: 10 weeks
amplitude of maximal opening
Kinematic parameters of movement: temporal parameters: amplitude of maximal opening
Time frame: 10 weeks
Trajectory of movement measured in the XY plane
Kinematic parameters of movement: spatial parameters: Trajectory of movement measured in the XY plane
Time frame: 10 weeks
height of elbow and wrist at the moment of grasping an object, measured in mm in the YZ plane
Kinematic parameters of movement: spatial parameters: height of elbow and wrist at the moment of grasping an object, measured in mm in the YZ plane
Time frame: 10 weeks
muscular force evaluated by muscle testing performed by a physiotherapist
muscular force evaluated by muscle testing performed by a physiotherapist (score from 0 to 5)
Time frame: 10 weeks
joint amplitude evaluated in degrees (°) by the physiotherapist
Time frame: 10 weeks
Box and Block test
Box and Block test performed by an occupational therapist
Time frame: 10 weeks
Minnesota test.
Minnesota test performed by an occupational therapist
Time frame: 10 weeks
amplitude of electrodermal responses
mental chronometric assessment associated with acquisition of electrodermal responses
Time frame: 10 weeks
duration of electrodermal responses
mental chronometric assessment associated with acquisition of electrodermal responses
Time frame: 10 weeks
Kinesthetic and Visual Imagery Questionnaire
The Kinesthetic and Visual Imagery Questionnaire (KVIQ) will allow a qualitative evaluation of the mental representation capacity of patients
Time frame: 10 weeks
This study is completed, as verified in Aug 2016. You cannot join it, but the record below documents what was studied.
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Hospices Civils de Lyon